Transcript Quad-Rat Vitals Monitor

Quad-Rat Vitals Monitor
Advisor: Paul Thompson
Client: Dr. Alex Converse
Overview
PET Imaging
 Requirements
 Existing Devices
 Previous Semester’s Work
 Pulse Oximeter Probe Design Options
 LabVIEW Interface Design Options
 Where do we go from here?
 Acknowledgments

PET Imaging of Rats
Positron emission
tomography (PET)
scans to monitor
location of tracers in
rats
 Client scans four
anesthetized rats at a
time

◦ Needs to monitor the
rats’ vitals
http://homepages.cae.wisc.edu/~bme300/rat_monitor
_s09/reports/FinalPaperSpring09.pdf
Requirements: Quads Vitals Monitor

Client needs to simultaneously monitor
four rats
1) SpO2 levels, accuracy of ±2%
2) Heart rates up to 500 beats per minute
3) Respiratory rates of 20 to 30 breaths per
minute
4) Rectal temperatures of 93 - 100° F

Non-invasive probes and user-friendly
interface
Existing Devices

Existing devices:
◦ Client currently uses rudimentary devices to
monitor vitals
◦ Available: Pulse oximeter for mice and rats
 Over $7000, one rat at a time
http://www.starrlifesciences.com/mri.html
Previous Semester’s Work




Developed circuit for detecting
breathing rate using force sensing
resistor
Designed and calibrated
thermistor to detect
temperature
Designed Graphical User
Interface (GUI) in LabVIEW
displaying breathing rate and
temperature
Attempted to reverse engineer
existing Pulse Oximeter
Force sensing resistor
LabVIEW interface
General Probe Requirements
Applicable for rats of varying size
 Reusable
 Sufficient blocking of ambient light
 Compatible LED and Photodiode

http://www.oximetry.org/pulseox/principles.htm
Foot Clip

Pros:
◦ Similar to current device
◦ Easy to reposition
◦ Positioned far from the
head

Cons:
◦ Can displace easily
◦ Risk of LED/Photodiode
misalignment
◦ Potential to apply
excessive pressure
Foot Wrap

Pros:
◦ No displacement once
attached
◦ Alignment of
LED/Photodiode
maintained throughout
testing

Cons:
◦ Not adjustable
◦ More involved cleaning
process
Tail Clip

Pros:
◦ Easy to attach
 No confusion over
placement location
◦ Adjustable

Cons:
◦ May interfere with
catheter in tail
◦ Potential to apply
excessive pressure
Design Matrix – Pulse Oximeter Probe
Criteria
(Weight)
Foot Clip
Foot Wrap
Tail Clip
Ergonomics(20)
18
12
14
Cost (5)
4
5
4
Accuracy (50)
46
46
35
Safety (10)
8
9
8
Durability (10)
9
6
9
Feasibility (5)
4
5
4
Total (100)
89
83
74
Four Corners with Buttons
Full display
Four Corners with Buttons

Pros:
◦ Logical layout
◦ Important information
visible

Cons:
◦ Extra clicking
◦ History graphs
incomparable
◦ Less robust
A sample quarter of the final display
Tab Interface

Pros:

◦ Uncluttered interface
◦ Easy to program
Full display
Cons:
◦ Inefficient
◦ Data hard to compare
Four Corners with Histories
Full display
Four Corners with Histories

Pros:
◦ All data on one screen
◦ Easy to compare
trends

Cons:
◦ Cluttered interface
◦ Tiny on small screen
A sample quarter of the final display
Design Matrix – LabVIEW Interface
Criteria
(Weight)
Ergonomics
(45)
Programming
Feasibility (35)
Aesthetics (20)
Total (100)
4 Corners with
Buttons
Tabs
4 Corners with
Histories
38
25
44
26
32
30
15
79
18
75
14
88
Where do we go from here?

Finish LabVIEW GUI
◦ Determine how data will be collected from
Pulse Oximeter

Design pulse-ox probe to fit rat’s hind
paw
◦ Integrate with signal received from Graduate
Students’ circuit
Print circuit boards
 Fabricate housing apparatus

Acknowledgements
Professor Paul Thompson
 Dr. Alex Converse
 Amit Nimunkar
 Tim Balgemann
 Liz Ahlers
 Nate Werbeckes

Questions?