Transcript lesteriosis_in_animal_0

Lesteriosis in
animal
By
Mariam Magdy Abdel Motaleb
Salma N. el yamany
defination
*Is an infection but not
contagious disease.
* (life_threating disease)
*it is called circling disease .
*Also winter_spring disease of
feedlot or haused ruminant.
Pm lecture
26/10/2015
Listeria monocytogenes bacteria
1/ it is a gram positive
2/extremely antibiotic resistant coccoid to bacillus
shaped bacteria found in environment
3/ live in soil ,in poorly made silage & spoiled
forages & DI tract & mammary GI
4/found in feces of infected birds , wild mammals
fish ,insects& fetal feces
( meconium)
5/shedded in nasal discharge, uterine discharge,
aborted fetus
Pm lecture
26/10/2015
Listeriosis is most
prevalent during spring &
winter months , w`
suggests prevalance of l.
monocytogenes thus
management practice can
be applied to minimize the
risk of infection
Pm lecture
26/10/2015
*Common in domestic animal
( domestic mammals & poultry)
espacially adult ruminant w` are
feed contaminated silage than
human beings
*Newly born , elder ages &
pregnant.
Pm lecture
26/10/2015
1)through ingestion of contaminated feed or water 
or by fecal shedding of bacteria
(( oral _fecal route ))
2) through inhalation
N.B
**Infected animal could die if improperly treated
**Zoonosis cosumption of contaminated
unpasteurised milk by human can lead to
meningitis & meningoencephalitis
if pregnant , abortion
Pm lecture
26/10/2015
Listeriosis can be presented in
3 forms
Abortion
septicemia
Encephalitis
Pm lecture
26/10/2015
Abortion Form
NOTE
PATHOGENESIS
* Abortion up to 12 days later
e` purulent exudate covering
placenta.
* In ewes & does & cows
occuring last third of
pregnancy.
Septicemia
Form
Encephalitis
Form
* In monogasteric An` &
young Ru` ( 1 to 3 years old )
>> listeriosis presents
differently causing
( septicemia) w` can also be
fatal.
*Ch`ch` by encephalitis or
meningoencephalitis
(inflammation of brain)
& highest mortality rate
*Death can follow clinical signs
acutely is within 24- 48 hrs.
1) If >. The uterine infection
Bacteria
occurs early during this period mouth
fetus dies quickly as result of
multply
septicemia & get autolysed&
expelled.
The placenta is retained as
result of
mild metritis.
2) If> the fetus is near term
when infection develops
dystocia is the rule e` severe
metritis & msepticemia in dam.
body
Bacteria
body
opening
blood sream
in mucosa of oral cavity
spread to oragn brain
multiplies
inflammation
Abortion Form
Septicemia
Form
1) Abortion
or
2) stillbirth.
1) Diarrhea.
2) Abortion.
3) Death.
1) Early clinical signs are
depression , decreased appetite.
2) decreased milk production.
3) Fever.
4) Neuromuscular incoordination
w` An` circle in same direction.
5) Facial nerve paralysis (on one
side).
6) Ear drooping , salivation.
7) Lack jaw , imparied swelling .
8) Death.
1) In fetuses
necrotic
foci in the liver & spleen .
2) In placenta
necrosis
of placental villi & become
covered by purulent exudates
1) Small focal necrotic
lesion found in liver & all
organs ( milliary
abscesses).
2) in very young an`
gastroenteritis may be
1) The meninges are thickened by
greenish edema.
2) Grayish foci of softening may
be found in the cross section of
medulla.
SIGNS
pm
LESIONS
Encephalitis
Form
Abortion
Form
MICRO
Septicemi
a Form
Encephalitis Form
1) Micro abscesses in brain.
2) Vasculitis in white matter.
3) Perivascular cuffing.
4) Meningitis.
5) Area of malacia ( softening)
due to thrombosis
Listeriosis called e`…...&….&…..
Q1
Q2
Q3
• Route of infection is ingestion only ??
• Pathogenesis of septicemia ?short note
•
Signs of encephalitis……&….&….&…..
Q4
Q5
Q6
Pm lecture
Micro appearance of encephalitis 1)….
2)…. 3)……..
PM lesion in abortion form 1)…… 2)….
26/10/2015