Transcript Antimicrobial Resistance Surveillance

Antimicrobial Resistance
Surveillance
(AMR Surveillance)
AMR Surveillance of N. gonorrhoeae
• Treatable sexually transmitted
infections affect 300 million
people a year
• Gonorrhoea accounts for
about 62 million infections a
year
BUT
• Gonorrhoea is becoming increasingly resistant
to antibiotics
• AMR surveillance of N. gonorrhoeae is important
What is GASP?
• GASP is the WHO's Gonococcal Antimicrobial
Surveillance Programme
• GASP has set up networks of laboratories in
more than 50 developing and developed
countries around the world (Sri Lanka is one
of the focal point laboratories participating in
GASP)
• which collect isolates of the bacteria that
cause gonorrhoea from patients and test their
resistance to the antibiotics used to treat
gonorrhoea (According to SOP manual)
AMR surveillance of Neissaria gonorrhoea in Sri Lanka
• Method:
Cross sectional study of all GC culture positive
samples from the central clinic and from few
peripheral STD clinics during each year are
taken as the study sample.
Disk diffusion method is used to monitor the
resistance patterns
Antibiotics used in testing
1.
2.
3.
4.
5.
6.
7.
Penicillin
Tetracycline
Ciprofloxacin
Nalidixic acid
Spectinomycin
Cefuroxim
Ceftriaxone
0.5IU
10 µg
1 µg
30 µg
100 µg
30 µg
0.5 µg