Transcript trade-offs
Objectives
1.Use data (evidence) to make claims about
variation, fitness, selection and evolution in
populations.
2.Apply the general definition of Natural
Selection and the concept of trade-offs to
specific cases (e.g., guppies and antibiotic
resistance in bacteria)
Sex and Guppies
http://www.pbs.org/wgbh/evolution/sex/guppy/gallery.html
Trade-offs
Initial population: Mostly drab
LOW level of predation
Time 1:
Number of guppies: 227
Number of generations: 5
Number of weeks: 112
Time 2:
Number of guppies: 232
Number of generations: 12
Number of weeks: 407
Trade-offs
Initial population: Even mix
HIGH level of predation
Time 1:
Number of guppies: 171
Number of generations: 4
Number of weeks: 57
Time 2:
Number of guppies: 100
Number of generations: 7
Number of weeks: 203
Trade-offs
What would happen if...
Initial population:
•EVEN mix of guppy coloration
•MEDIUM level of predation?
What would the population look like after
7 generations? Make a prediction.
You can test your prediction at:
http://www.pbs.org/wgbh/evolution/sex/guppy/low_bandwidth.html
Trade-offs: define
Each trait may have both costs and benefits.
It is impossible for any population of organisms
to evolve optimal solutions to all agents of
selection at once.
Antibiotic resistance
• Do you use antibacterial soap? Why
or why not? Discuss in your groups.
Reading in Angel:
Microbes: What They Do & How Antibiotics
Change Them
Maura Meade-Callahan
CQ
Mutation acts directly on ….
A.
B.
C.
D.
E.
DNA
RNA
Amino acids
Protein
Phenotype
CQ
Fitness is ….
A. Absolute
B. Relative
Antibiotic Resistance in Bacteria:
an experimental approach
Antibiotic Resistance in Bacteria:
an experimental approach
1. Redraw this model and
label:
a) Bacterial lawn
b) Inhibition zone
c) Discs of antibiotics
2. Label a point on the
model where bacterial
are likely most resistant
to the antibiotic.
Variation and Antibiotic Resistance
1. Do you think there is
variation among these
bacteria? Explain.
Variation and Antibiotic Resistance
1. Do you think there is
variation among these
bacteria? Explain.
2. What is the origin of this
variation?
3. Is the variation heritable?
Fitness and Antibiotic Resistance
1. Does the environment
vary across the Petri
plate?
Fitness and Antibiotic Resistance
1. Does the environment
vary across the Petri
plate?
2. Are these bacteria
equally fit in all
environments?
Antibiotic resistance: Selection
Describe this graph.
What can you say
about:
1.Variation?
2.Fitness?
3.Selection?
Antibiotic Resistance:
putting it all together
Create a model that demonstrates
the evolution of an antibioticresistant bacteria population.
Label your arrows with processes!
Start
Key to figure:
• Blue = antibiotic-sensitive bacteria
• Orange = antibiotic-resistant bacteria
• x = antibiotic
End
Antibiotic resistance
• Has your opinion about antibacterial
soap changed?
Reading in Angel:
Microbes: What They Do & How Antibiotics
Change Them
Maura Meade-Callahan