Transcript ch 18 clicker questions

CLICKER QUESTIONS
For CAMPBELL BIOLOGY, NINTH EDITION
Jane B. Reece, Lisa A. Urry, Michael L. Cain, Steven A. Wasserman, Peter V. Minorsky, Robert B. Jackson
Chapter 18
Regulation of Gene Expression
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Questions prepared by
Louise Paquin
McDaniel College
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What does the operon model attempt to
explain?
a) the coordinated control of gene expression in
bacteria
b) bacterial resistance to antibiotics
c) how genes move between homologous regions
of DNA
d) the mechanism of viral attachment to a host cell
e) horizontal transmission of plant viruses
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At which stages of gene expression are
bacteria usually regulated?
Eukaryotes?
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Gene Regulation
Each of a group of bacterial cells has a
mutation in its lac operon. Which of these will
make it impossible for the cell to metabolize
lactose?
a) mutation in lacZ (β-galactosidase gene)
b) mutation in lacI (cannot bind to operator)
c) mutation in operator (cannot bind repressor)
d) mutation in lacI (cannot bind inducer)
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Operon
What elements from the following list constitute
a bacterial operon?
a) repressor gene
b) promoter
c) inducer
d) all of the above
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Transcription Factors
General transcription factors in eukaryotes are
needed for all genes using the same RNA
polymerase. What is the function of specific
transcription factors? Of enhancers?
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Approximately what proportion of the DNA in
the human genome codes for proteins or
functional RNA?
a) 83%
b) 46%
c) 32%
d) 13%
e) 1.5%
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Alternative Products
A specific gene is known to code for three
different but related proteins. This could be due
to which of the following?
a) premature mRNA degradation
b) alternative RNA splicing
c) use of different enhancers
d) protein degradation
e) differential transport
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miRNA
A given RNA transcript
forms numerous hairpin
loops that are cut (diced) to
form short double-stranded
noncoding sequences.
How can these resulting
strands affect gene
expression?
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Developmental Regulation
In the development of a multicellular organism,
differential gene expression is responsible for
both differentiation and sequential regulation.
Write a plausible hypothesis for how one of
these could occur in the formation of the heart.
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Embryo Formation
Scientists showed that bicoid mRNA, and then
its Bicoid protein, is normally found in highest
concentrations in the fly’s anterior. Predict
what would happen if Bicoid were injected at
the posterior end.
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Oncogenes
Which of the following would not typically
cause a proto-oncogene to become an
oncogene?
a) gene suppression
b) translocation
c) amplification
d) point mutation
e) retroviral activation
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Multistep Cancer Causation
How does the multistep model of colorectal
cancer illustrate how an individual might inherit
a “predisposition” for a particular type of
cancer?
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