WHAT THE HECK IS A VIRUS
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Transcript WHAT THE HECK IS A VIRUS
Viruses
What is a virus?
How does a virus work?
How are viruses stopped?
WHAT IS A VIRUS?
NOT AN
INDEPENDENT LIVING
ORGANISM
VARIED IN SHAPE
Enveloped (circular)
Helical
West Nile Virus
Polyhedral
VIRAL PARTS
Capsid- protein coat
Nucleic Acid
Membrane
(sometimes)
Surrounds capsid
Helps virus enter cell
How Viruses Replicate:
Lytic vs. Lysogenic
LYTIC CYCLE
TAKE OVER THE HOST
Replicate Viral DNA
Destroy Host Cell
West Nile Virus
Lysogenic Cycle
“Hides” in host
Replicates viral DNA, but does not destroy
cell
SARS Virus
HIV virus
Animations
Vaccinations
First Developed by Edward Jenner
Noticed milk maids DID NOT get smallpox
Developed smallpox vaccine by exposing
patients to cowpox
Allows patients to develop antibodies to
small pox virus
Vaccinations
Polio vaccine developed by Jonas Salk
Made the Polio virus inactive
Then exposed patients to inactive virus
Patients developed antibodies, but did not
get polio
Types of Viruses
Bacteriophages (infect bacteria/cells)
DNA based
Easier to deal with (usually)
Retroviruses and “others”
HIV
Influenza
HIV
Has RNA
RNA can mutate easily
Reverse Transcriptase (to make DNA)
Engulfed by white blood cells
(Does not inject)
Can remain “hidden” (lysogenic) for
long periods of time
Does not directly kill a person
Influenza
RNA
Engulfed by cells
Can kill, but usually just makes you
really sick
http://www.cssd11.k12.co.us/dohnts/Biology/bio04nt.htm
VIRAL DISEASES
Influenza
HIV
Polio
Polio
Small Pox
HIV
Ebola
Hantavirus
Hepatitis A-E
Influenza
SARS
Bird Flu
Common Cold
HPV
Can Viruses Be Good?
Possibilities in genetics
Fixing genes (Virus injects “good” DNA)
Cystic Fibrosis
Spinal Injuries…