Transcript The Oral Systemic Link and the Future of Patient Care

The Oral Systemic Link and
the Future of Patient Care
Jamie Toop, DDS
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About Me…
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“I would give all my possessions
for a moment in time”
WHAT ARE THE 7 LEADING CAUSES OF
DEATH IN AMERICA? (according to the
CDC)
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Leading Causes of Death
1. Heart Disease
2. Cancer
3. Chronic Lower Respiratory Diseases
4. Stroke
5. Accident
6. Alzheimer's
7. Diabetes
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WHAT DO THESE CONDITIONS
HAVE IN COMMON?
Six of the top seven leading causes of
death in America have been associated with
conditions in the mouth.
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“The View” on Oral Systemic Link
• https://www.youtube.
com/watch?v=XLDL8Nh
NxWA
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1. Heart Disease Associations
Research Has Shown:
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Brushing < 2x/day = ↑ risk
Gum disease → 60% ↑ risk of heart disease
Gum disease → heart disease death 2x as likely
Gum disease and cholesterol levels predictors
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Gum Disease—
Heart Disease Mechanism
Infection/inflammatory components in gums
• Enter blood stream
• Can be carried to heart/coronary arteries
• Limits blood flow
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2. Cancer Associations
Research Has Shown:
• Gum disease → 62% ↑ risk (pancreatic/kidney)
• Pancreatic cancer
• 4th leading cause of cancer-related death
• Detection difficult
• 5 year survival rate 21.5% if detected early
• Pancreatic cancer ↑ bacteria levels in saliva
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Other Cancer Associations
Research Has Shown:
Men with gum disease
• ↑ associations of gum disease and cancer
• 30% ↑ risk to develop cancers of the blood
• ↑ risk of prostate cancer
• ↑ level of prostate-specific antigen secretion
• Saliva test in development may detect sooner
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3. Chronic Lower Respiratory
Associations
Research Has Shown:
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Oral cavity may play central role
Relationship between oral hygiene and COPD
Gum disease bacteria can be aspirated in lungs
Respiratory pathogens can colonize in teeth
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4. Stroke Association
Research Has Shown:
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Gum disease →3x ↑ likelihood to die from stroke
Severe gum disease 4.5x ↑ risk of stroke
Correlation ↑ in men and in those under 60
Gum disease bacteria enters blood stream
• Plaques form, can dislodge and enter brain
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5. Alzheimer’s (AD) Association
Research Has Shown:
• AD irreversible - prevention key
• Declines in oral hygiene shown in AD patients
• Loss of teeth from gum disease ↑ AD risk
• Gum disease bacteria enters blood stream
• Can cause neuroinflammation
• Limits neurotransmitter activity
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6. Diabetes Association
Research Has Shown:
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Diabetics with gum disease 3.2x ↑ risk of death
Diabetic control ↑ with improved oral hygiene
Infection/inflammatory components move in blood
More research to establish causal relationship
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Causal vs. Correlative
Relationship of Oral/Systemic
Link
Can we establish a causal relationship?
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GINGIVITIS—MATH AND
VERBAL RECALL ASSOCIATION
According to
webmd.com, using
antimicrobial
mouthwash or
toothpaste can make
you less bad at math.
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LET’S DO SOME “CALCULUS”
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Pick a number between 1 and 10 (though
this will work with any number)
Double it
Add 10
Divide by 2
Subtract your original number
WHAT NUMBER DO YOU HAVE?
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IF YOU DON’T HAVE…
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WHAT TO WATCH OUT FOR…
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Credibility of the publication
Parameters of the study
Repeatability
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Be careful to throw out what you know is true
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Erectile Dysfunction (ED)
Research Has Shown:
• Men in 30s with gum disease 3x ↑ risk of ED
• Infection/inflammatory components in gums
• Travels in blood stream, forms plaques
• Limits blood flow
• Can cause impotence - blood vessel damage
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Pre-term Birth
Research Has Shown:
• Mothers with gum disease
• 85% chance pre-term/low birth weight
• Gingivitis 3x ↑ risk
• Moderate gum disease 8x ↑risk
• Oral bacteria in pre-term placentas
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Oral Systemic Link and the
Future of Patient Care
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More research to establish causal relationships
Draw conclusions from existing data
Detection/prevention of disease far from oral cavity
Nothing to lose in treating gum disease
• Eliminating can ↑ life by 6.5 years!
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So, tell your patients to:
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Then, tell them to:
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And finally, tell them:
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