Transcript Group_4_Infections

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Hip hemiarthroplasty after displaced femoral neck
fracture: a survivorship analysis
Femoral neck fracture – broken knee joint
• Total Hip Arthroplasty – Yes….better results for
patients than internal fixation and hemiarthroplasty.
• Some Results for age group 60 + differ from this:
“0-35 % dislocation cases” – quite high
 REASON ? Major one is comorbidities!
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Biomarkers as a Tool for Management of
Immunosuppression in Transplant Patients
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Immuno-suppressive drugs
Without immunosuppression therapy,
transplatation surgery could be fatal.
Therapeutic drug monitoring –
DOES NOT reflect adverse effects to immune cells.
Pharmacodynamic monitoring (biomarkers)
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Problem of infection in the ICU
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Infections possible - ventilator-associated
pneumonia, catheter-associated urinary
tract infection, catheter-related
bloodstream infection
Need to be attentive to horizontal infection
and use proper antibiotics for multiresistant bacteria like MRSA.
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Managing infection in the critical care unit:
how can infection control make the ICU safe?
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Infection Control in the ICU
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Device Related Nosocomial Infection In ICU
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Antibiotic Resistance
Pathogens
Ventilator Associated
Pneumonia
Catheter-related
Infections
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Risk Factors
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Modifiable
◦ Frequency of ventilator
circuit changes
◦ Antibiotic usage
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Prevention
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Nonmodifiable
◦ Patient age and gender
◦ Severity of illness
◦ Coma
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Bronchoscopic
techniques
Nonbronchoscopic
techniques
Balance between
initial antibiotic and
overuse
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Decrease Infection in
Neonatal Intensive Care Unit
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Long-Term Acute Care Hospital
Hand
Hygiene
Active
Surveillance
Culture
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Pursuing perfection in fighting with
VAP and CR-BSIs in ICU
Bundle Methodology
VAP rate per 1,000
device days
CR-BSI rate per 1,000
device days
1997
2004
2002
2004
Medical ICU
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8.2
3.4
Surgical ICU
Similar declines
10.5
4.5
Burn Center
Similar declines
9.5
1.85
Year
VAP: Ventilator-Associated Pneumonia
CR-BSIs: Catheter-Related Bloodstream Infections
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