Ex. 20 Antibiotic Disk Sensitivity
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Transcript Ex. 20 Antibiotic Disk Sensitivity
Antibiotics
Naturally occurring compounds produced by bacteria
and or fungi, that kill or inhibit other microbes
Many Antibiotics are produced by
2 Genera of Bacteria
Streptomyces
Bacillus
1 Fungal Genus
Penicillium
Common Antibiotics
Stretomycin –
Streptomyces
Protein synthesis
70S Ribosme
Bacitracin -
Bacillus
Cell Wall synthesis
Penicillin -
Penicillium
Cell Wall synthesis
Selective toxicity
The antibiotic must harm the pathogen without
harming the host cell
Antibiotics do this by:
1. Attacking the 70S Ribosome (Protein synthesis)
2. Attacking the Cell Wall
Kirby-Bauer Antibiotic Disk
Sensitivity Test
Kirby-Bauer Antibiotic Disk
Sensitivity Test
MIC
Minimum Inhibitory Concentration
Least amount of an antibiotic that will inhibit the
growth of a microbe
MRSA
Methicillin Resistant Staphylococcus aureus
Vancomycin
Last line of defense against MRSA – which has led to
VRE
Vancomycin Resistant Enterococci