Transcript Non-invasive Microwave Breast Cancer Detection

Non-invasive Microwave Breast Cancer Detection - A
Comparative Study
Arezoo Modiri, Kamran Kiasaleh
University of Texas at Dallas
Why New modality for Breast Cancer Detection
in Needed?
http://www.cancer.org/acs/groups/content/@epidemiologysurveilance/documents/document/acspc-031941.pdf
Why Microwave-Based Diagnosis?
Frequent checkups need in-vivo, inexpensive, noninvasive, and convenient methods with
acceptable accuracy.
MRI:
- Expensive
- Not tolerable for some
Women (e.g. implant cases)
X-Ray:
- Ionizing,
- High false negative
detection rate
(20%)
- In many cases,
Painful
Ultrasound:
- Operator-dependent
- High false positive detection rate
(The false-positive rate is three times of that of X-ray => unnecessary biopsy.)
http://www.cancer.gov/cancertopics/factsheet/detection/mammograms
Why Microwave-Based Diagnosis?
Microwave radiation is not ionizing and the heating effect
is not harmful at low power levels (less than OSHA
standard of 10 mW/sq. cm.)
Penetration depth is acceptable for breast monitoring
Microwave technology is mature; thus, manufacturing
microwave devices is relatively easy & cost-effective
The standard component size at microwave band has the
potential of creating a handheld, portable device
Are Any Other Research Groups Working
On This Subject?
Dr. Paul Meaney – DartMouth
Dr. Susan Hagness – University of Wisconsin
Dr. Elise Fear – University of Calgary
Dr. Magda El-shenawee – University of Arkansas
Dr. Sima Noghanian – University of North Dakota
Dr. Natalia Nikolova – McMaster University
Dr. John Stang – Duke University
Other Studies Target Clinical Applications
This Study’s Ultimate Goal
Portable, Self-Examine Tool which compensates for the
defects of mammography by making check ups easier
and more affordable for women and sending them to Xray or MRI monitoring only when a signature is detected.
3D Radiator Design
The 3D radiator design was done in Ansoft HFSS
The digital phantom created by Ansoft was used
In order to have a full coverage of the tissue, hemisphere shape
was chosen with 16 curled bent dipole antennas
Design frequency was chosen to be 1.2GHz since this was the
longest antenna we could fit inside our structure
Resonance Performance of The
Antennas
1.2 GHZ
The Two Versions of The Radiating
Structure
One without conductive cover
One with a conductive cover added for
Electromagnetic Shielding
– Cause no interference
– Accept no interference
– Only the outer surface of the structure is covered by a
conductive layer
Different Tumor Cases Are Considered
Different tumor shapes
Different tumor sizes
Different tumor locations
Electric Field Changes Are Studied
Both magnitude and phase contrasts are
considered.
Cancerous model is exactly same as the normal
one except for having one of the tumors inside it
How Signatures Are Analyzed
The signatures
above a certain
threshold are
added up.
Simulation Results for Two Tumor
Cases
Specific Absorption Rate on Cut Plane
OSHA Compliance
SAR is 3.5W/Kg at
the hottest spot.
The sphere is filled
with fat.
1000 centimeter
cube of fat is almost
equal to 0.9Kg.
At the hottest spot, the power distribution is
equal to (3mW/cubic cm) which is well
below the OSHA standard of (10
mW/square cm)
Conclusion
By studying a variety of tumor cases, it was shown that,
overall, adding a conductor cover as electromagnetic
shielding, not only creates an interference-free environment
for measurement, but also significantly increases the cancer
detection chance.
Thank you!
Any Questions?
[email protected]