Transcript Can PET/CT and PET FDG predict Chemotherapy response in lung

Can PET/CT and PET FDG
predict Chemotherapy
response in lung cancer
patients?
By: Megan Broscious
Introduction:



Cancer is the leading cause of death in the
United States.
More people did from lung cancer than
any other type of cancer.
Not every patient responds to
chemotherapy.
Methods



100 male and 100 female cancer patients will be
evaluated with PET/CT and or FDG PET to
predict which patients will respond to treatment.
The 200 patients will be evaluated weekly for a
period of 7 weeks, as they undergo 2 courses of
docetaxel and carboplatin.
The prospective data will be attained by using a
nominal level of measurement and a Chi-square
Goodness-of-Fit statistical test.
Methods…



A positive response will be represented by
a negative slope and significantly different
from zero.
A negative response will be represented
by a positive slope or one that was not
different from zero.
The patients will then be followed for one
year to see if the results were correct.
Results

The results of several conducted studies
show that PET/CT and or FDG PET can
potentially predict which patients will
respond to treatments in week one and
week three of chemotherapy.
Implications


With this new technology, patients will
have the option to cease chemotherapy if
they are not responding, saving them from
the grueling side effects of chemotherapy.
Patients also have the option to select a
new treatment plan.
Costs:

PET scans are more
costly than other
diagnostic imaging
scans.
Conclusion

More studies are needed to completely
validate the results of these studies. With
this in mind, according to studies done,
PET/CT and or FDG PET do have the
ability to predict chemotherapy response
in lung cancer patients.