Transcript Retinoblastoma

Retinoblastoma
By Nathan Raine and Max
Barna
What is Retinoblastoma?
Retinoblastoma is a type of cancer
that forms on the eyes.
Retinoblastoma is caused by a
deletion of chromosomes 13, 14, 15,
21, and 22.
This is a frameshift mutation.
How can you get it?
Eye color is the gene that can code
for retinoblastoma.
Children age six are most affected.
Retinoblastoma is a cancer but has
no carcinogens so receiving it is
completely genetic (X-linked).
What are the symptoms?
The pupil may appear white at
certain angles.
Most are cross-eyed with poor vision.
Eventually, if not treated, a tumor
will form on the eye.
What is the treatment?
Without a tumor or a small tumor,
retinoblastoma is cured by simple
means of laser eye surgery.
With a large tumor, Chemotherapy
will be needed as well as laser eye
surgery.
Odds
Luckily, retinoblastoma has a 9598% cure rate.
Most that were not cured were the
only to die from retinoblastoma.
No matter how severe, all types of
retinoblastoma can be cured.
Only 2% of all who are cured
become blind after treatment.
Other Information
Retinoblastoma is part of the deletion of 5
chromosomes which makes it extremely
unlikely.
If you are older than 19, you cannot be
diagnosed with retinoblastoma because
your eyes stop developing at age 19.
Two organization websites for more info:
http://www.ncbi.nlm.nih.gov/pubmedhealt
h/PMH0002025/,
http://ghr.nlm.nih.gov/condition/retinobla
stoma
Photos of Retinoblastoma
Photo of
retinoblastoma
www.geneticpeople
.com
Karyotype of
person affected by
retinoblastoma.
www.haligonia.com