Transcript Cancer
Cancer Cells Gone Wild! Cancer Cell • Surrounded by T-cells and dead How are cancer cells different from most cells? • Do not have a normally functioning cell cycle • Divide excessively and can invade other tissue Tumor • Abnormal mass of cells • Skin Lung Normal vs . Tumor Growth Benign Vs. Malignant • Benign-mass of normal cells at original site • Malignantcancerous and can spread to other cells Tumor • Abnormal mass of cells Metastasis • Spread of cancer cells beyond their original site Metastasis of prostate tumor cells • Into bone cells Carcinogens • Any substance involved in the promotion of cancer: • gamma rays, X-rays, UV rays • Dioxin (pesticide) • Tobacco smoke • Asbestos • HPV virus Cancers are named • According to the tissue or organ in which they originate 4 types of Cancers • Carcinomas • Sarcomas • Lymphomas • Leukemias Carcinomas • Cancers that originate on external or internal coverings (skin, lining of intestine) Carcinoma Forming Sarcomas • Arise in tissue that support the body (bone and muscle) leukemia • cancer in leukocytes (white blood cells) in bone marrow • (too many white blood cells and not enough red blood cells) lymphomas malignant cells in the lymph • system Lymphatic System • Works with circulatory system to filter clear fluid • (transports white blood cells) • Lymphatic System You Tube Cancer Populations Cancer Gene Checker • The p53 Tumor Suppressor Gene Triggers Cell Suicide FYI p27 on chromosome 12 • Inhibitor of cdk regulator of cell cycle • High levels of p27 shown in breast cancers Normal Cell Divisions • Mammalian Cells will divide about 50 times in a culture 3 ways to treat cancer • 1. Surgically remove • 2. Radiation • 3. Chemotherapy Surgically Removal Radiation Treatment • To kill cancer cells Usually X-rays and gamma rays to target the cancer cells Chemotherapy Drugs Cancer Fighting Drugs: work on mitotic spindles • TAXOL • VINBLASTIN • Paclitaxol • Prevents mitotic • Freezes the mitotic spindles from spindles after it forming forms • From periwinkle • From Yew plant