Transcript The Genetics of Harry Potter

The Genetics of Harry
Potter Creatures
Mr. Nichols
PHHS
Objectives
The Student will be able to:
1.) Review concepts in Punnett and Pedigree Genetics
Cartoon of the Day!
Time for Some
Competition!
Prize: Bio Bucks…Duh!
Our First Genetic Case
Study!
When Queen Victoria of England was seventeen, she met
one of her many cousins, Prince Albert of Saxe-Coburg. She
fell deeply in love with him, and several years later, when
they were both twenty years old, Victoria proposed to Albert.
They were married on February 11, 1840; both were
deliriously happy, and Victoria made Albert Prince Consort,
giving him an equal say in the running of the country. What
neither of them knew at the time was that Victoria was
carrying the gene for hemophilia.
Your Mission!
You are a genetic detective tasked with figuring out what type
of inheritance pattern this disease is following in Queen
Victoria’s family pedigree.
You’ve conducted your preliminary research and constructed a
rough pedigree of the family history. You’ve also concluded
that the disease is not autosomal.
Fluffy: The Three Headed Dog
Fluffy Problems
Three-headism in Dogs is very uncommon (obviously), however
there exists two genes that when in combination give an offspring
with three heads. These two genes have alleles A and B that
when both homozygous recessive yield the condition. Apply this
and determine how many of the offspring will have the three
heads.
1.) Dog 1 Heterozygous x Dog 2 Heterozygous
- (for both genes)
2.) Dog 1 Heterozygous x Dog 2 Homozygous Recessive
-(for both genes)
Giant Spiders!
Spider Problem
These species of Giant spiders have venom that can mutate the
genes in the human genome.
One afternoon Harry and Ron are walking through the Dark
Forest and are both bitten by a Giant Spider. Remarkably they get
away and maintain a healthy life style. Little did they know that
their sex cells will now permanently behave differently when they
fertilize eggs.
Harry: Bbrr x Ginny bbrr (B-Brown hair, b-Red Hair, R-four legs
r- two legs )
All offspring that are heterozygous for any hair color have their
alleles mutated to blonde color. How did this affect the offspring
distribution?
Dragons!
Dragon Problem
All current dragons can trace their family history back to a single
mating pair. These two dragons had 5 offspring, three sons and
two daughters.
The three sons all found lady dragon friends, two of those
couples had two offspring, all boys, the other son and his mate
had three offspring all daughters.
The two daughters found gentlemen friends with great hair and
had children. One couple had four children, two males and two
females. The other couple had two daughters who were identical
twins!
Draw this pedigree
Dragon Problem Cont’d
All Male dragons have a terrible genetic disease that
drastically affects their ability to catch prey and breath fire.
The family of 6 has it’s two daughters affected by the disease
as well.
Determine what type of inheritance pattern this disease
could follow.
The Genetics of Harry
Potter Creatures: Day 2
Mr. Nichols
PHHS
Cartoon of the Day!
Mountain Troll!
Trolling!
Troll breeding is a tricky and lucrative business. When
breeders select for a certain trait in trolls they must follow a
1:2:1 genotype distribution relationship.
If Allele “R” determines a trait for brain size what
genotype(s) must the breeder use to maintain the ideal
genotype distribution relationship?
How might this specific breeding affect the troll population?
The Hippogriff
Create a Hippogriff
Hippogriff Problem
Hippogriffs are created by mating a Male Hippo with a
Female Griffin (try not to imagine how the courtship works).
However there is a problem, when a certain allele
combination is present the infant dies shortly after birth
100% of the time. Homozygous Dominant is the lethal
genotype.
Hippogriff Problem Cont’d
Draw a 3 generation pedigree, starting with 2 heterozygous
parents and always producing 4 children (have each child
represent one of the punnett square genotypes). Have all offspring
mate with outsiders who have the ‘healthy’ homozygous
condition. Draw a line through all dead infant Hippogriffs.
What trends do you notice?
How has this genetic disease affected the Hippogriff population?
Weasley Family Pedigree
R- Red Hair, r- Brown Hair or blonde
hair.
-Assign Genotypes
-Determine Inheritance Pattern