Transcript Microbial Genetics - Gene Transfer

Microbial Genetics - DNA
Transfer
Review of Information Transfer in Cell
 Recombination
 Transfer of DNA &Genetic
Recombination in Bacteria
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– Conjugation
– Transformation
– Transduction
Microbial Genetics - DNA
Transfer
Microbial Genetics - DNA
Transfer
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Recombination – process by which DNa is
broken and repaired resulting in an exchange
of DNA between two DNA molecules to form
new combinations of genes
Eukaryotic - crossing over during meiosis
Prokaryotic - occurs when DNA is transfered
from one cell to another (transfer from a
doner to a recipient)
Microbial Genetics - DNA
Transfer
Genetic
Recombination
Microbial Genetics - DNA
Transfer
Conjugation
Microbial Genetics - DNA
Transfer
Normal or Low Frequency Conjugation
Microbial Genetics - DNA
Transfer
High Frequency Conjugation
Transformation
Transduction
Microbial Genetics - Regulation
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Three types of regulation
– Constitutive - gene is always turned on
– Repression - gene is normally turned on
but can be turned off in response to a
metabolic signal
– Induction - gene is normally turned off but
can be turned on in response to a metabolic
signal
Microbial Genetics - Regulation
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Types of Regulation
of mRNA synthesis
– Induction - lac
operon
– Repression - trp
operon
Microbial Genetics - Regulation