Transcript Genetic Diseases and Gene Therapy

Gene Therapy
and
Genetic Engineering
Your Goals:
• Create a Concept Map to organize what
you know about gene therapy.
• Use the Learn.Genetics gene therapy
website to help you.
• Integrate what you have learned about
Genetic Engineering into your Gene
Therapy Concept Map.
• Gene Therapy Vector Engineering Project.
Concept Map Overview
• A concept map is a technique used
to organize information or thoughts.
• Concept maps allow you to organize
lots of information into a form that is
easily understood.
• Concept maps allow you to visualize
connections within the information.
Gene Therapy Word List
• Targeting the right
tissue
• Immune response
• Vectors
• Single gene
disorders
• Naked DNA
• Activating the gene
• Disruption of existing
genes
• in vivo
•Integrating the gene
•Fit inside vectors
•Keys to success
•Viruses
•Candidate diseases
•Liposomes
•Procedure
•Integration into the
germline
•Risks/Challenges
•ex vivo
Gene Therapy
AND Genetic Engineering
Word List
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Plasmids
Hemophilia
Identical DNA copy
Recombinant DNA
tools
ADA Deficiency
Restriction Enzymes
Adeno Associated
virus
Sickle Cell Anemia
• Herpes Simplex
Virus
• Identical organism
copy
• Ligase
• Huntingtons Disease
• Retrovirus
• Cloning
• Adenovirus
Creating a Concept Map
Step 1
– Start by placing your Main Idea in the
center circle or graphic.
Step 2
– Decide which of the choices are your
Large Topics and place them in a
circle around your Main Idea.
– Draw lines connecting the Main Idea
and the Large Topics.
Large topic
Large topic
Ma in Id e a
Large topic
Large topic
Creating a Concept Map
Step 3
– Decide which Subtopics belong with
each Large Topic and place them near
the appropriate branch.
• Cut the Topics out of the Word List
so you can easily rearrange them
until you have it right.
– Paste your Concept Map to your
poster.
Concept Map!
subtopics
Large topic
Large topic
subtopics
Ma in Id e a
Large topic
subtopics
Large topic
subtopics