Transcript Regulation of Gene Expression

Regulation of Gene
Expression
Pages 351-377
Key Concepts
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Bacteria often respond to environmental change by
regulating transcription.
Eukaryotic gene expression can be regulated at any
stage.
Noncoding RNAs play multiple roles in controlling
gene expression.
A program of differential gene expression leads to
the different cell types in a multicellular organism.
Cancer results from genetic changes that affect cell
cycle control.
18.1 Bacteria often respond to
environmental change by regulating
transcription.
Operons- Tryp and Repressible Operon
Lac Operon- An inducible enzymes
Positive Gene Regulation
18.2 Eukaryotic gene expression can
be regulated at any stage.
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Differential Gene Expression
Regulation of Chromatin Structure
Histone modification
DNA Methylation
Regulation of Transcription Initiation
Stages of gene expression that can be
regulated
Eukaryotic Gene Organization
Enhancers and Activators
Mechanisms of Post Transcriptional
Control
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RNA processing
mRNA degradation
Initiation of Translation
Protein processing and Degradation
18.4 A program of differential gene expression
leads to the different cell types in a multicellular
organism
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Cell Differentiation
Morphogenesis
Cytoplasmic determinants and Inductive
signals
Determination and Differentiation
Pattern formation
Determination and Differentiation of
Muscle Cells
Life cycle of drosophilia
From egg to larvae
18.5 Cancer results from genetic
changes that affect cell cycle control
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Oncogenes and proto oncogenes
Tumor suppressor genes
Proto-oncogenes can become
oncogenes
Cell cycle stimulating pathway
Cell cycle inhibiting pathway
Effects of Mutations
Multistep path to cancer