Transcript Caveat Emptor

WEB-BASED INFORMATION
RESOURCES:
F I N D I N G D R U G D AT A S T AT
OBJECTIVES
• Discover techniques for effectively locating and utilizing webbased information resources.
• Analyze the most appropriate drug information resources,
including primary, secondary, and tertiary sources for
answering questions related to clinical research and practice.
• Analyze evidence-based medicine resources and clinical
guidelines/trial resources used in the literature retrieval
process.
• Realize the vast number of resources available for drug
information.
• Describe key advantages and disadvantages of using free
web-based search engines versus online subscription web
sites.
OVERVIEW OF DRUG INFORMATION
RESOURCES
• Primary literature:
• Most up-to-date resource available
• Journal articles
• Secondary literature resources:
• Indexing and abstracting systems
• Easy retrieval of primary resources
• Tertiary Resources:
• Condense and summarize data from the primary literature
• Textbooks
• Electronic databases
SEARCH ENGINES
General Web-searching principles apply.
Caveat Emptor – “Let the buyer beware”
Verify, validate, and confirm the information is correct
Web search engines may help quickly locate relevant materials.
Not reliable for producing a comprehensive, verifiable,
repeatable set of citations – use MEDLINE, EMBASE, IPA,
etc.
Features of Electronic Tertiary Databases
Clinical Pharmacology
Facts & Comparisons answers
LexiROM
Micromedex
Comprehensive 23,000 U.S and
Foreign Drugs
Drug Identification
Search by NDC number
search by partial or complete NDC
Drug Interactions
drug-drug,
duplications, drug-food,
ethanol, lab, tobacco,
caffeine
drug-drug, drug-disease, duplications,
allergy, drug-food, ethanol, lab,
tobacco, pregnancy, lactation
drug-drug,
drug-lab, drug-food,
allergy, herbal,
pregnancy, OTC
Trissel's 2
Trissel's 2
Laboratory
Information
Chart of normal
laboratory values
Chart of normal laboratory
values
King's Guide to
Parenteral
Admixtures
Pertinent information
in monographs
chart of normal
laboratory values
drug-drug,
duplications, allergy,
drug-food, ethanol,
lab, tobacco,
pregnancy, lactation
Trissel's 2
IV Compatibility
Patient Counseling
English and Spanish
Drug, oncology-specific administration,
Drug, disease and
Drug, disease, and
OTC administration techniques,
disease-focused; English and Spanish
procedural information;
19 languages including
English and Spanish
procedural; English,
Spanish, and 13 other
languages;
customizable
Through Tox and
Drug Product Lookup
Through REPRORISK
Materials
Individual laboratory
value monographs
Inert
ingredients
Teratogenicity
information
Located in how supplied
section
Pertinent information
in monographs
Located under product list
Not readily available
Uses Briggs' Drugs in Pregnancy
and Lactation
Breastfeeding
information
Investigational
drug monographs
Complimentary and
alternative medicine
FDA recalls
Drug shortages
Material Safety Data
Sheets
Referencing
Available platforms
Cost
Pertinent information
in monographs
Yes, readily referenced
Uses Briggs' Drugs in Pregnancy
and Lactation
Limited information
ThroughTOXNET,
Hazardous substance
database
ThroughTOXNET,
Lactmed
Limited
Yes
Through Natural
Product Database
Link to FDA
Link to FDA
No
Yes; AltMedDex
No
No
No
Through review of Natural
Products
Weekly FDA news thread
Weekly FDA news thread
No
Comprehensive
Web-based, PDA
Subscription required;
Limited
Web-based, PDA, print
Subscription required for basic and
Limited
Web-based, PDA. Print
Subscription required
Extensive
Web-based, PDA
Subscription required;
30 day free trial available
free access to students
advanced packages
for individual
components; package
prices available
Various package
proves available
Through REPRORISK
Yes, readily referenced
No
No
Yes; AltMedDex
NATIONAL LIBRARY OF MEDICINE
• Medline is freely accessible via PubMed
• http://nlm.nih.gov
FREELY ACCESSIBLE DRUG
INFORMATION
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National Library of Medicine
Databases
PubMed/MEDLINE
MeSH
UMLS
ClinicalTrials.gov
MedlinePlus
TOXNET
Images from the History of Medicine
LocatorPlus
All NLM Databases & APIs
NATIONAL LIBRARY OF MEDICINE
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Find, Read, Learn
Search biomedical literature
Find medical terminologies
Search NLM collections
Read about diseases
Learn about drugs
Explore history
Find a clinical trial
Use a medical dictionary
Find free full-text articles
NATIONAL LIBRARY OF MEDICINE
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Drug Information from the National Library of Medicine
Drug Information Portal
The Portal provides users a comprehensive gateway to information on more than 20,000 drugs (over 200,000 unique
searchable drug names and their synonyms) not only from NLM but also from other U.S. government agencies. It covers
drugs from the time they are entered into clinical trials through their entry into the U.S. market place. The Drug Portal
touches on all related information resources at NLM to provide for a comprehensive view. It is intended as a "middle ground"
resource which includes information for the consumer, health professionals, and researchers.
Drugs, Herbs and Supplements
Learn about your prescription drugs and over-the-counter medicines from MedlinePlus, the National Institutes of Health's
Web site for patients and their families and friends. Read about side effects, dosage, special precautions, and more. Browse
dietary supplements and herbal remedies to learn about their effectiveness, usual dosage, and drug interactions.
Pillbox
Developed to aid in the identification of unknown solid dosage pharmaceuticals, Pillbox combines high-resolution images of
tablets and capsules with appearance information (imprint, shape, color, etc.). It enables users to identify solid dosage forms
based on physical criteria: imprint (characters or number printed on a medication), shape, color, size, and scoring. Users are
shown thumbnail images of possible matches. These images are continually updated as the user enters additional
information. Pillbox is designed for use by emergency physicians, first responders, other health care providers, Poison
Control Center staff, and concerned citizens.
DailyMed
DailyMed provides information about marketed drugs, including FDA labels (package inserts). It provides health information
providers and the public with a standard, comprehensive, up-to-date, look-up and download resource of medication content
and labeling as found in medication package inserts.
Dietary Supplements Labels Database
The database links you to the information from the labels of over 4,000 dietary supplement products in the marketplace,
including vitamins, minerals, herbs or other botanicals, amino acids, and other specialty supplements. It includes name,
form, active and inactive ingredients, amount of active ingredient, manufacturer/distributor information, label claims,
warnings, percentage of daily value, and additional label information. The database can be searched by product names, text
terms found on product labels, specific dietary ingredients, and manufacturers.