Transcript Nutrients

 Nutrients=any substance in food that is used by
the body to promote normal growth, maintenance,
and repair.
 Essential nutrients must be consumed in the diet.
 There are six classes of nutrients.
 Overview
 Classes of nutrients: Carbohydrates, Lipids, Proteins,
Water, Vitamins, Minerals
 RDA - recommended dietary amounts
 Energy value of foods - kilocalorie - amount of heat
energy to raise the temperature of 1 kilogram of water 1
degree Celsius
 Composed of C, H, O
 Provide a major source of
fuel for the body
 Basic unit is glucose
 Simple versus Complex
 Energy yielding (4 kcal
/gm)
Carbohydrates
 Divided into simple carbohydrates and complex
carbohydrates
 Used in the process of ATP synthesis
 Simple carbohydrates examples: soft drinks, candy,
fruit, ice cream, pudding
 Complex carbohydrates: bread, cereal, crackers, flour,
pasta, nuts, rice, potatoes
 RDA - 125-175 grams = 55-60% of total caloric intake
Lipids
 Classes: triglycerides, phospholipids, sterols
 Used in cell membrane synthesis, energy production,
vitamin storage
 Animal sources: lard, meat, poultry, eggs, milk, milk
products
 Plants sources: chocolate, corn soy, cottonseed, olive
oils, coconut, peanuts
 Cholesterol sources: organ meats and egg yolks
 RDA - 80-100 grams = 30% or less of total caloric
intake
Proteins
 20 amino acids 9 essential and 11 non-essential
 Used in synthesis of enzymes, antibodies, hemoglobin,
muscle, etc...
 Complete or incomplete depending if the source has
all amino acids needed by the body
 Complete protein sources: eggs, milk meat (fish,
poultry, pork, beef, lamb)
 Incomplete protein sources: legumes, nuts and seeds,
grains and cereals
 RDA - 0.8g/kg of body weight = 10-15% of total caloric
intake
 Vitamins
 Two classes
 Fat soluble - A, D, E, K
 Water soluble - C (ascorbic acid) and B
B1: thiamine
B2: riboflavin
B3: nicotinamide (niacin)
B5: pantothenic acid
B6: pyridoxine
Biotin
B12 cyanocobalamin
Folic acid
 Uses
 Antioxidants (A,C&E),
 Hormone synthesis (D)
 Required for clotting proteins (K)
 Coenzymes (B vitamins)
 RDA varies with each vitamin
 Minerals
 Seven required (calcium, phosphorus, potassium,
sulfur, sodium. chloride, and magnesium)
 Trace minerals needed (fluorine, cobalt, chromium,
copper, iodine, iron, manganese, selenium, zinc)
 Uses in bone formation, nerve transmission, cofactors
of enzymes, protein synthesis, etc....
 Metabolism
 sum of all the reactions occurring in the body at any given
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time; a balance between catabolic and anabolic reactions
Catabolism – breakdown of complex organic compounds
into simpler ones; reactions and are considered exergonic
(gives off energy) and produces more energy than they
consume
Anabolism – combining small organic compounds into
larger ones; reactions are endergonic (requires energy) and
consume more energy than they produce
Chemical reactions of living systems depend on efficiently
transforming energy from one molecule to another. ATP
(adenosine triphosphate) accomplishes this task.
ATP à ADP + P + ENERGY
 Composed of three pathways: Glycolysis, Krebs cycle,
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and Electron transport chain
ii. Glucose actively transported in GI tract then
insulin-mediated facilitated diffusion in body cells
iii. Glycolysis
Occurs in the cytosol
One six carbon glucose is split into two three carbon
pyruvate
2 ATPs are used but 4 are created
2 nicotinamide adenine dinucleotide (NAD) are
hydrogenated
 Krebs Cycle
 Pyruvate from glycolysis is converted into Acetyl CoA
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in cytosol (NAD is hydrogenated and carbon dioxide is
released)
Acetyl CoA is shuttled into the mitochondria
Series of reactions takes place
One ATP is created (per Acetyl CoA)
2 carbon dioxides are released
3 NADs are hydrogenated
One flavin adenine dinucleotide (FAD) is
hydrogenated
 Electron Transport Chain
 Occurs in the inner mitochondrial membrane
 Electrons and hydrogens are released from NADs and
FADs
 Oxygen is the final electron acceptor -- if no oxygen
present lactic acid produced from pyruvate and krebs
does not occur -- referred to as anaerobic carbohydrate
metabolism
 Hydrogen ions form a concentration gradient
 A total of 36 ATP are produced from the complete
breakdown of a glucose molecule.
 Water and carbon dioxide are released as by
products.
 Chemical Equation for the entire reaction:
C6H12O6 + 6O2
6H20 + 6CO2 + 36 ATP + heat
 Lipogenesis=
triglyceride synthesis
 Lipolysis=
“fat splitting”
 Metabolic rate=the body’s rate of energy output
 Basal metabolic rate=the minimum energy
expended in a fasting state (12 hours) to keep a resting,
awake body alive in a warm, quiet environment.