Transcript Slide 1

Deamination of amino acids
The amino acids serine and threonine can be deaminated directly
For example, serine  pyruvate + ammonia
The first step is dehydration, in
other words removal of water
The second step is hydrolysis,
leading to the removal of ammonia
O
O
O
H2C
HO
H3C
OH
NH2
OH
OH
NH2
O
H2O
serine
NH 3
pyruvate
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