Transcript Interactions - CML Advocates Network

Integrative Oncology
Complementary Medicine and
Interactions
Dr. Senckenbergisches Chronomedizinisches Institut
Fachbereich Medizin
Goethe-Universität Frankfurt am Main
Arbeitsgemeinschaft
Prävention und Integrative Onkologie
Deutsche Krebsgesellschaft
Doctor,
what can I do by myself???
A lot, but be careful!
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Whole medical systems: TCM, Ayurveda, Homeopathy, Naturopathy
Mind-Body Medicine: Meditation, Prayer, Art, Music therapies
Biological based therapies: herbs, vitamins, minerals, dietary
supplements, dietary changes
Manipulative and body-based pracitices: massage, chiropractic,
osteopathic manipulation
Energy therapies: acupuncture, Reiki, Qigong, therapeutic touch
Alternative Medicine is not Complementary Medicine
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How significant is the subject of complementary and alternative
medicine for patients with CML in your country?
Joint survey run by
PRIO and CML
Advocates Network:
responses from
27 countries
In your country, who offers treatment access to complementary and
alternative medicine? (If need be: multiple answers)
In your country, will CML patients generally inform their
oncologist about their using complementary medicine in
particular when undergoing conventional medicine at the
same time?
In your country, who pays for treatment with complementary
and alternative medicine?
How to find information
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Groh Verlag
What is the problem?
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How to make sure, that you are doing the right things
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Evidenced based medicine
Efficacy and not only effects
Side effects
Interactions
Costs
The tumor and the immune system
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Nutritional supplements
1. If they are effective than they most probably are forbidden
2. If they are not forbidden they most probably don‘t work
3. There could be some exceptions
R. J. Maughan, Institut für Sport und Trainingswissen-schaften, Loughborough-Universität, England
Examples
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Vitamin D
Selenium
Omega-3-fatty acids
Interactions
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Interactions via enzymes
Resorption
Interaction at the receptor
Interaction in the tumor cell
Anthocyane, Curcumin, EGCG,
Ellagsäure, Glycyrrhiza glabra,
Indol-3-carbinol, Leinöl, Melatonin,
Omega-3-Fettsäuren, Oridonin,
Selen, Silimarin, Traubenkernöl,
Zeolite
EGF
Leinöl, Lignan
EGFR
Tyrosinkinase
RAS
Carnosol, EGCG,
Granatapfel, Proteaseinhibitoren, Resveratrol,
erhöht: Betaglucan
Allylsulfide, Auraptene,
Bromelain, Curcumin, Cyclolignane, Deguelin, EGCG,
Genistein, Granat-apfel,
Honokiol, Indol-3-Carbinol,
Inositol-Hexa-phosphat,
Isothio-cyanate, Kaempherol,
Lycopin, Magnolol, Melatonin,
Quer-cetin, Resveratrol, Selen,
Sojasaponine, Vitamin D,
Vitamin E, Zeolite
PI3K
AKT
Curcumin,
EGCG, Vitamin
E, Oridonin
MAPK
Anthozyane, Apigenin, Auraptene, Baicalin,
Bromelain, Cannabinoide, CAPE, Capsaicin,
Chlorogensäure, Chrysin, Cumarin, Curcumin,
EGCG, Ganoderma, Genistein, Gingko, Ginseng,
Granatapfel, Ingwer, Isothiocyanate, Kaempferol,
Kaffeesäure, Knoblauch, Melatonin, Nobilitin,
Oleanolsäure, Omega-3-Fett-säuren, Oridonin,
Perillylalkohol, Proanthocyane,
Proteaseinhibitoren, Resveratrol, Saiko-saponin,
Scutellaria, Selen, Traubenkernöl, Vitamin D,
Weidenrinde, Wogonin
Consequences of drug interactions
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Reduction of the side effects of the cancer drug
Reduction of the effect of the cancer drug
Potentiation of the side effects
To enhance quality of life
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Die Schule des
kreativen Sehens
W. Rolfes, J. Borris,
F. Pölking. B. Volmer
Integrative Oncology: it‘s about your aims and your way!
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