Airway Stents
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Transcript Airway Stents
Airway Stents
Henry Bauer and Viviana Martinez
Lung Cancer
Lung cancer – uncontrollable growth of
abnormal cells in the lung(s) form masses
of tissue or tumors
• Malignant
• can spread to nearby tissues or other
organs
• 2 main types
-Non-Small Cell Lung Cancer
-Small Cell Lung Cancer
• In 2009 - 205, 974 people were
diagnosed with lung cancer
-158, 081 people died from lung cancer
Lung Cancer
•
Non-Small Cell Lung Cancer is most common
• Accounts for ~85% of all diagnoses
• Four stages:
Stage 1: cancer is localized to lungs
Stage 2: cancer has spread to nearby lymph nodes
Stage 3: cancer has spread to lymph nodes in the middle of the chest
Stage 4: advanced disease; cancer has spread to both lungs, fluid
around the lungs, and/or to other tissues and organs
•
Small Cell Lung Cancer
• 2 stages:
Limited: cancer in one part of a single lung plus nearby lymph nodes
Extensive: cancer has spread throughout the chest, other tissues, and
organs
Symptoms
• Damage to the lungs and surrounding
tissues/structures
• Persistent and/or worsening cough
• Coughing up blood
• Wheezing or shortness of breath
• Chronic pneumonia or bronchitis
• Chest pain
• Fatigue
Risk Factors
•
Smoking ( #1 cause) or
second hand smoke
•
Tuberculosis or other lung
diseases
•
Environmental exposure
to carcinogens
•
such as asbestos, diesel
exhaust, and radon
•
Age
•
Family history
Treatment
• Surgery – remove lobe/section of lung with tumor
• Chemotherapy – drugs are used to shrink or kill the
cancer
• Carboplatin, Cisplatin
• Radiation
• Targeted drug therapy – drugs specifically target
cancer cells
• Tarceva, Avastin, Xalkori
Airway Stents
Types of Stents
EGIS Airway Stent
• drawstring for easy removal
• polishing process removes micro
cracks
• non-biodegradable silicone
membrane
• Nitinol for shape memory and
superelasticity
• barbs prevent migration
• available in a variety of types and
sizes (diameters and lengths)
Costs
Surgery costs $5000
Individual stents can be $1000-2000.
Median cost of removal surgery is $10,700.
Implantation Protocols
Sedation and bronchoscopy
Insert guidewire and sizing catheter to
measure size of obstruction.
Insert breathing tube to allow airflow during
insertion.
Deploy stent.
Secure stent placement.
http://www.sngbio.com/page/animation.ph
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Recovery and Patient Followup
Symptoms improve in 84%
of patients within 24 hours
Bronchoscopy check ups.
Monitor for coughing,
shortness of breath, etc.
Doesn’t require
immunosupressants
Long term complications
can require additional surgery
Complications
Migration of stent.
Trouble breathing.
Bleeding.
Pneumonia or other infection.
New airway obstruction from accumulated
secretions or tumor growth.
Stent fracturing.
Conclusion
• EGIS airway stent provides rapid relief of
symptoms and drastically improves quality of
life for patients.
• Provides time for chemotherapy or drugs to
take effect, or for conditions to improve and
allow for surgery.
•
Despite potential complications, airway stents
have proven to be versatile and effective.
http://www.nytimes.com/2013/04/30/science/
groundbreaking-surgery-for-girl-born-withoutwindpipe.html?emc=eta1&_r=0