Urinary Medications
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Transcript Urinary Medications
Urinary Medications
Copyright © 2012, 2009, 2006, 2003 by Saunders, an imprint of Elsevier Inc.
1
Urinary Tract Infections (cont’d)
Lower UTI
Acute cystitis
• Frequently in females
• E. coli, Staph, Klebsiella, Pseudomonas
• Symptoms
Pain and burning on urination, frequency, urgency
Urethritis, prostatitis
• Same symptoms
Copyright © 2012, 2009, 2006, 2003 by Saunders, an imprint of Elsevier Inc.
2
Urinary Analgesics
Phenazopyridine (Pyridium)
Dose is usually 100 mg PO BID X 7 – 10 days
Action
• Relieves pain, burning sensation, frequency, urgency
Side effects/adverse reactions
• GI upset
• Red-orange urine
• Blood dyscrasia
• Nephrotoxicity, hepatotoxicity
Copyright © 2012, 2009, 2006, 2003 by Saunders, an imprint of Elsevier Inc.
3
Urinary Antispasmodics
Oxybutynin (Ditropan)
Usual dose is 5 mg PO BID or TID
Extended release dose is 5 – 10 mg daily
Action
• Direct action on smooth muscles to relieve spasms
Side effects/adverse reactions
• Drowsiness, tachycardia, dizziness, fainting, blurred vision, dry mouth,
constipation
Caution
• Avoid in narrow-angle glaucoma, cardiac, renal, hepatic, prostate problems
Copyright © 2012, 2009, 2006, 2003 by Saunders, an imprint of Elsevier Inc.
4
Antiemetics (cont’d)
Nonprescription antiemetics
Antihistamines
Diphenhydramine (Benadryl)
Side effects (similar to anticholinergics):
Drowsiness, dry mouth, constipation, urinary
retention, risk for falls
Bismuth subsalicylate (Pepto-Bismol)
Action
Acts directly on gastric mucosa to suppress vomiting
Will turn stools black
In diarrhea, it adsorbs and slows GI motility
Antiemetics (cont’d)
Serotonin receptor antagonist
Ondansetron (Zofran) – covered previously
Dose is 4 – 8 mg PO BID or q6h as needed for nausea
Action
Blocks serotonin receptors in the gut and afferent vagal nerve terminals in
chemoreceptor zones in the brain
Use
Post-operative nausea, chemotherapy, general nausea
Side effects
Headache (most common side effect), diarrhea, dizziness, fatigue. If
neurological changes occur, STOP THE DRUG!
Please treat the nausea before it progresses to vomiting!
Antiemetics (cont’d)
Glucocorticoids
Dexamethasone (Decadron) – covered already KNOW THE SIDE
EFFECTS
Dose is 2 – 10 mg PO BID
Cannabinoids YOU WILL NOT BE TESTED ON THIS ONE BUT
YOU NEED TO KNOW IT
Dronabinol (Marinol) This is synthetic THC; this is used in health
care settings in place of medicinal marijuana
Side effects
Drowsiness, dizziness, dry mouth, impaired thinking, euphoria, mood
changes, headaches, confusion, depersonalization, nightmares,
incoordination, memory lapse, anxiety
Antiemetics (cont’d)
Nursing interventions
Provide mouth care.
Monitor vital signs, bowel sounds.
Monitor for dehydration.
Warn client not to consume alcohol when taking
an antiemetic.
Warn pregnant clients to avoid antiemetics.
Avoid driving motor vehicles.
Diarrhea
Causes
Spoiled foods or excessively spicy foods
Bacteria (Escherichia coli), virus, toxins
Drug reactions
Fecal impaction, laxative abuse
Malabsorption disorders, bowel tumor,
inflammatory bowel disease
Stress, anxiety
Antidiarrheals (cont’d)
Loperamide (Imodium)
Dose is usually 2 – 4 mg (1 to 2 capsules) four
times a day as needed
Do not exceed 8 capsules in a day – this can
cause significant bowel injury
Antidiarrheals (cont’d)
Nursing interventions
Monitor BP, R.
Report more than 10 to 15 mm Hg decrease in BP.
Monitor frequency of bowel movements and
bowel sounds.
Assess for evidence of dehydration.
Monitor electrolytes.
Avoid fried foods, milk, and sedatives.
If diarrhea persists after 48 hours, notify
healthcare provider.
Constipation
Causes
Bowel obstruction, fecal impaction
Chronic laxative use, ignoring urge to defecate
Neurologic disorders
Side effect of drugs
Lack of exercise
Insufficient consumption of fiber and/or water
Constipation (cont’d)
Laxatives
Laxatives: soft stool
Cathartics: soft to watery stool with cramping
Purgatives: watery stool with cramping
Types of laxatives
Osmotic (saline)
Stimulant (irritants)
Bulk-forming
Emollient (stool softeners)
Stimulant (Irritant)
Laxatives
Bisacodyl (Dulcolax)
Dose is 5 – 10 mg po daily as needed
Action
Increase peristalsis by irritating sensory nerve endings in
intestinal mucosa
Results
Orally 6 to 12 hours, suppository (rectal) 15 to 60 minutes
Side effects
Abdominal cramps, weakness, reddish brown urine,
diarrhea
There is also a bisocodyl that is a softener as well
Emollients (Stool
Softeners)
Docusate (Colace)
Dose is 100 mg PO BID
Action
Lowers surface tension
Promotes water accumulation in intestine
Emulsifies and lubricates feces for easier passage
Used whenever someone is on opioids
Use with caution around children. It looks like a
jelly bean and children have eaten them!
Emollients (Stool Softeners)
(cont’d)
Use
Prevent constipation
Reduce straining post surgery or myocardial
infarction
Side effects
Abdominal cramping, nausea, vomiting, diarrhea