Transcript how to check for possible drug interactions).

Drug interaction webpages
How to search for possible drug
interactions on the internet?
SCART online – ITM 2007
Selected webpages for drug interactions
In the following presentation you will learn how to search
for drug interactions on interactive webpages and what
information you can find on static webpages. Here a
selection of possible sources of information:
1.
2.
3.
4.
5.
http://www.hivinsite.com/arvdb?page=ar-00-02
http://www.medscape.com/druginfo/druginterchecker (this
webpage requires registration, however it is for free!)
http://www.hiv-druginteractions.org/
http://www.tthhivclinic.com/interact_tables.html
http://www.thebody.com/treat/interactions.html
If you would like to exclude a possible drug interaction, it is
highly recommended to check at least two different
websites!
Selected webpages for drug interactions
1. www.hivinsite.com/arvdb?page=ar-0002
This is an interactive webpage where you
can make a query. The next slides show
you how to do a query to check for a
possible drug-drug interaction.
This option you choose if you want to know a druginteraction with a certain antiretroviral drug
This option you choose if you want to know a druginteraction with a drug which is not a antiretroviral drug
This option you choose if you want to get an overview of
the drug-interactions of a certain drug class
Step 1: you select the option “search by
antiretroviral drug”
Example:
you would like to check if
the combination of
nevirapine and
ketoconazole could lead to
a possible drug-interaction
To place a query you need to know the name of the active molecule of the
drug (generic name, e.g. nevirapine). In case you have just the brand
name (e.g. Viramune) you could check the following webpages first to find
out the generic name: www.google.com, www.drugs.com
Step 2: you select “nevirapine” in the
list of antiretroviral drugs
Step 3: you select “by individual drug”
to check the interaction with
ketoconazole
Step 4: you press the button “submit”
Step 5: you select “ketoconazole” and
press the button “submit” at the end of
the list
Would you co-administer
ketoconazole with nevirapine?
NO, they advise not to coadminister these two drugs
together
Selected webpages for drug interactions
2.http://www.medscape.com/druginfo/druginterche
cker
This is an interactive webpage where you can make
a query. The next slides show you how to do a query
checking a possible drug-drug interaction.
On this webpage you can search by generic drug
name or by the brand name.
This webpage is requiring registration first, however it is
for free!
Step 1: this database is working with
generic names or with brand names,
so you can type “nevirapine” or
“Viramune” in the text box and press
“go”
Step 2: one or more options are shown
in the result box, you select the option
you want to check
We are taking the same
example:
you would like to check if
the combination of
nevirapine and
ketoconazole could lead to
a possible drug-interaction
Step 3: you “click to add” and the
chosen option appears in the patient
regimen box
Step 4: you type “ketoconazole” (or
Nizoral) in the text box and press “go”
Step 5: you select the option you are
interested in and press “click to add”
Step 6: the combination of nevirapine
and ketoconazole could lead to
interactions, for more information press
the button “click here”
Here the result of your
query with detailed
information and
severity level of the
drug interaction!
Selected webpages for drug interactions
3. http://www.hiv-druginteractions.org/
This is an interactive webpage where you
can make a query. The next slides show
you how to do a query to check for a
possible drug-drug interaction.
Click here to access the druginteraction charts
You can choose between different
options, depending on what you would
like to check!
To place a query you need to know the name
of the active molecule of the drug (generic
name, e.g. nevirapine). In case you have just
the brand name (e.g. Viramune) you could
check the following webpages first to find out
the generic name: www.google.com,
www.drugs.com
We are taking the same
example:
you would like to check if
the combination of
nevirapine and
ketoconazole could lead to
a possible drug-interaction
Step 1: you choose option 1
Step 3: you click on “next”
Step 2: you click on “nevirapine”
Step 5: you click on next
Step 4: as ketoconazole is an
antifungal, you click on “antifungals”
Step 7: you click on next
Step 6: you click on
“ketoconazole”
Step 8: you can see in the
description above that ketoconazole
should not be coadministered with
nevirapine; if you click on the red
button you will get more detailed
information
Here you get the result
of your query with
detailed information!
Selected webpages for drug interactions
4.http://www.tthhivclinic.com/interact_tab
les.html
5.http://www.thebody.com/treat/interactio
ns.html
These are static webpages containing
drug interaction tables. The next slides
show you some examples of what
information you get.
This drug-interaction
webpage is static and here
you can access druginteraction tables for
example
You are at the end of the presentation.