Transcript 14. MP and MPM that contain flavonoids of cholagogue, diuret

Lecture 8
MP and MPM containing flavonoids
with cholagogue, diuretic and
diaphoretic activity
MP and MRM containing flavonoids
with diuretic activity
Diuretic is any drug that elevate the rate of
urination and thus provides a means of forced
diuresis.
Bidentis Herba Bidens tripartita- Three-lobed
Beggarticks, Three-part
Beggarticks, Burr Marigold
Asteraceae
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Constituents. Flavonoids: luteolin
glucoside, khalcones, aurones,
condensed type tannins (6,5%),
coumarines, carotin, ascorbic acid,
mucilage, microelements (Mn).
Uses. Infusion has diuretic,
diaphoretic anti-bactericide action,
normalises the metabolism. It is used
internally to treat bladder and kidney
problems, blood in the urine, uterine
bleeding, ulcerative colitis and peptic
ulcers.
Oil extract has anti-inflammatory and
wound healing properties. Also
externally is used to treat alopecia.
Equiseti arvensis Herba
Equisetum arvense- Field
Horsetail, Common Horsetail
Equisetaceae
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Constituents. Flavonoidsderivatives of apigenin,
luteolin, kempferol and
quercetin; grass also contain
phenolcarbolic acids, tannins,
saponnins. The plant also
concentrates molybdenum and
selenium.
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Uses. Has a multibiological
action: diuretic, haemostatic,
anti-inflammation, litholitic and
detoxical action when
poisoned with Pb. Extract is a
part of Marelin, Phytolit,
Phytolisin, Traskov mixture,
Arphazetin.
Ononidis Radices – Restharrow Roots
Ononis spinosa- Field Restharrow
Fabaceae
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Constituents. Roots contain
izoflavonoids (1,5-2,5%):
formononetin, ononin, onosid,
onospin; ether oils, tannins,
triterpenoid saponins.
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Uses. Decoction has diuretic and
haemostatic medicines in treatment of
haemorrhoids, tincture and
Flavanobol have anabolic activity.
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In homeopathy fresh roots are used
as a diuretic in treatment of ascites (is
the accumulation of fluid in the
peritoneal cavity, most commonly due
to cirrhosis ans severe liver diseases)
and nephrolithiasis (the process of
forming kidney stone).
Centaureae cyani Flores – Cornflower Flowers
Centaurea cyanus- Cornflower, Bachelor’s button
Fam. Asteraceae
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Constituents. Flowers
contain antocyanes (0,61%)- cyanin, pelargonidin
derivatives; flavones;
flavonols; rutin; saponnins;
coumarin cycorin; pectines,
alkaloids etc.
Uses. Infusion is the light
diuretic and used in
treatment of kidney
diseases, bladder. Also has
cholagogic, antiinflammatory and
disinfectant functions.
MRM containing flavonoids
with diaphoretic action
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Diaphoretic is a herb or substance which
induces sweating (perspiration).
Tiliae Flores - Lime Flower
Tilia cordata – Lime Tree
Fam.Tiliaceae
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Constituents. The flavonoid
constituent comprise quercetin
glycosides (rutin, hyperoside,
quercitrin, etc.) and kaempferol
glycosides (tiliroside, astragalin).
Mucilage, a small proportions of
volatile oil. Phenolic acids are
also present.
Uses. Lime flowers are
diaphoretic, antispasmodic and
expectorant drugs and often are
used in conjunction with other
herbs as a nerve tonic, for the
treatment of catarrh and
indigestion, and for the alleviation
of headaches.
Sambuci nigrae Flores - Elder
Flower
Sambucus nigra – Sweet Elder
Caprifoliaceae
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Constituents. The drug contains a small
portion of a semi-solid volatile oil
consisting of free acids, principally
palmitic acid. Flavonoids (up to 3.0%)rutin predominates, with smaller quantities
of isoquercetrin, astragalin and
hyperoside together with the aglycones
quercetin and kaempferol. Other
constituents are triterpenes, triterpene
acids, other plant acids (chlorogenic, pcoumaric, caffeic and ferulic acids and
their β-glucosides), sterols, mucilage,
tannin and traces of sambunigrin.
Uses. Elder flowers are administered
principally as an infusion or herbal tea for
the treatment of feverish conditions and
the common cold. It acts as a diaphoretic,
also has diuretic properties, also has
expectorant properties.
MRM which contain flavonoids
with cholagogue activity
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Herbs with cholagogue activity promote
and regulate the normal production and
release of bile acids, therefore minimizing
liver- and gallbladder-related diseases.
Helichrysi arenarii Flores –
Helicrysum Flowers
Helichrysum arenariumHelichrysum. Yellow immortellee
Fam. Asteraceae
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Constituents. Flavonoids
(6.5%) mainly consist of flavanon
naringenin and its glycosidessalipurposide, izosalipurposide
and helichrysyn; from flavones
apigenin and it’s 5-glycoside are
available. Tannins, ether oil,
coumarines, sterols, organic
acids, mucilage and carotenoids
are present in dwarf everlast.
Uses. Infusion, dry extract,
herbal teas, and mixes. Flamin
are cholagogic edicines.Promote
gastric and pancreatic secretion.
Tanaceti Flores – Tansy
Flowers
Tanacetum vulgare- Tansy
Asteraceae
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Constituents. Flavonoids (2.5%)apigenin derivatives, acacetin,
luteolin; alcaloids, tannins, ether
oils (0.2%), organic acids are also
present.
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Uses. Medicines have cholagogic
action, tonic action on
gastrointestinal system, decrease
heart rhythm, increase blood
pressure. The powder has
anthelmintic action and used as
aromatic bitter. Also used for
treatment migraine, neuralgia,
rheumatism, bloating and loss of
appetite Tanacechol is used to
treat hepatitis, enterocolitis, low
acidity gastritis. Can cause
miscarriages.
Gycyrrhhizae Radices – Liquorice Root
Glycyrrhiza glabra - Liquorice
Fam. Fabaceae
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Constituents. More than 30
flavonoids and isoflavonoids, including
liquiritigenin, liguiritin, chalcones
isoliquiritigenin, isoliquiritin, and
neolicuoriside, glabrol, neoliquiritin,
hispaglabrinin A and B; coumestanes;
coumarins; triterpenoid saponins
glycyrrhizin and others.
Uses. As an antiphlogistic and
spasmolytic in gastritis and stomach
ulcers. As an axpectorant with
secretolytic and secretomotor action
for coughs and bronhial catarrh.
Medicines: Likvriton and Flakarbin
used for stomach ulcer.