Venom - BACK
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Transcript Venom - BACK
Venom
Historical and Modern Uses
Presented by Erin Hill
Basilisk
Greek Origin
Possible distortion
of cobra or asp
Giant serpent or
serpentine rooster
Immensely
venomous!
Overview
Venomous Creatures
Ancient Uses
Science
Modern Uses
Venomous Creatures
Insects
Wasps
Sting is similar to bees’
Not fatal, but painful, swollen bites
Termites
Explosive chemical warfare!
Some soldiers can “self-detonate” to take out enemies
Centipedes
Females more poisonous than males
Ants
Possibly fatal in allergic persons
Scolopendra (technically not an insect)
Bee
Ant
Termite
Arachnids
Black Widow
Bite is rarely fatal
Spider is generally non-aggressive
Brown Recluse
Fatal bites are rare
Tarantula
Again, rarely fatal
Scorpions
1050 species dangerous to humans
Tarantula
Brown Recluse
Black Widow
Scorpion
Marine
Jellyfish
Tentacles armed with nematocysts
Lionfish
Immediate pain from sharp spines
Stingray
Few fatalities
Result from a tail impact to chest area
Cone Shell
Highly toxic snails
Stingray
Lionfish
Jellyfish
Cone Shells
Amphibians
Poison Arrow/Dart Frogs
Famous
for vibrant colors and toxicity
Gather toxins from digested insects
Salamanders
Like
frogs, secretes poison through skin
NOT a danger to humans
Poison Arrow/Dart Frogs
Reptiles
Gila Monster
Bite hard and HANG ON
Rattlesnake
Not as highly toxic as cobras
VERY aggressive nature
Coral Snake
Follow red-yellow-black color pattern
Sea Snake
Closely related to cobras
Coral Snake
Rattlesnake
Gila Monster
Sea Snake
Mammals
Soricidae
Related
to moles
Poison flows through front teeth during
biting
Platypus
One
of two oviparous mammals
Males possess sharp, poisonous spurs on
their inner hind legs
(detail of Platypus spur)
Platypus
Soricidae
Ancient Uses
Healing and Religion
Ants
Were
used to treat skin diseases 2000
years ago
New Guinea: sutures!
Native American: Honeypot Ants
Africa: Nile tribes used them to cure
neurological disorders
Bury patients in a formicary (ant-farm)
Narcotics
Spanish Fly
Actually
a type of beetle
Popular ingredient in aphrodisiacs
Produces an itching sensation to exposed skin
Weapons
Ants
American Tropics: allow Army Ants to “march”
through homes to clear out pests
Sea Cucumbers
South Pacific: toxic entrails used to poison fish
Poison Dart Frogs
South America: true to their common names, are
still used to coat darts and arrows for hunting and
warfare
Science
What’s Inside
Stingers
Scorpions,
Insects
With insects, stinging mechanism is usually
ripped out after one attack
Fangs
Snakes,
Spiders
Toxin in injected directly into the blood
– Often causes no damage externally or when
ingested
Nematocysts
Jellyfish
Whip-like stinging cell
Spines/Spurs/Barbs
Lionfish,
Stingray
Poisoning by contact with sharp surfaces
Other
Frogs,
External excretion
Cone
Salamanders
Shell
Stinging radula (tongue)
Sea Scorpion with Poison
Spine
Jellyfish with
Nematocysts
Snake Skull with Hollow Fangs
How They Work
Most stings/bites from poisonous animals are
not life threatening
Many animals attack only when there in no other
option
Health is compromised if:
Very young or very old
Sick, immunodeficient, or severely allergic
Amount of toxin ingested/applied
Strike contacts chest or face
Dermatonecrotic
Causes
lesions and burning to exposed
tissues
Example: Box Jellyfish
Neurotoxin
Cause
paralysis or respiratory system,
cardiac system
Example: Cone Shell
Must
be injected or ingested
Modern Uses
Bees!
Apitherapy
Refers
to the use of honeybee (O.Apidae)
venom for medicinal purposes
Melittin: very potent anti-inflammatory
Apamin: enhances nerve transmission
Dopamine: neurotransmitter similar to
adrenaline
Seratonin: emotion-regulating neurotransmitter
Current Applications
Relieve arthritis and asthma
Relief from acute conditions like tendonitis and chronic
conditions like back/neck pains
Can be used to soften and break down scar tissue
Future Applications
Treatment for Multiple Sclerosis
– Prolonged treatment time, but better overall results
In this case, the usual symptoms of reaction
(itching, swelling, etc.) are the desired effect
Bee venom is used directly from the source
Bees, handled by experienced keepers, are allowed to
sting the patient locally
Storing the venom decreases the potency
Poison Arrow Frogs
Batrachotoxin
One of the strongest animal toxins
Some frog-eating snakes are immune
A single drop interferes with nerve impulse transmission
Heart may stop functioning
What makes their system different?
Before the heart stops, it is thrown into
hypercontraction
Small amounts could be used as a cardiac stimulant after
a heart attack
Sea Cucumber
Holothurin
Blocks
nerve impulses
Many side effects:
Prevents tumor growth
Regulates heart rate
Improves metabolism
Provides glycosides
– Cardiac varieties increase force of heart contractions
Scorpions
Giant Israeli Scorpion
Peptide
Chlorotoxin can be isolated from
the venom
Only attaches to cancerous cells
When paired with a chemotheraputic agent
(samporin), makes a drug that targets and
attacks only cancerous cells
Snakes
Some venoms can be used in small
doses to prevent blood clots
Snake Milking
A relatively
harmless way to extract
snake’s venom
Snake is coaxed to “bite” glass bowl/jar lid
Collected venom is used to make “anti-venom”
to treat snake bites
Milking a Snake
Applying Anti-venom to a Bite
(Most) Photos and Information
Courtesy of:
“Poisonous Plants and Animals”
Team C007974, ThinkQuest 2000.
http://library.thinkquest.org/C007974/