Transcript Slide 1 - Bionext

Skin Care and Science in Harmony
Concert has discovered a novel dermatological ingredient, MDI 101, that improves
the health of the skin. This discovery has generated the finest cosmetics available.
Discovery
✦First developed as a topical drug for dermatology under FDA approved IND
45,548
✦ MDI 101 was designed, synthesized, and tested in 1986
✦Preclinical Studies proved efficacy and safety in photo damage repair and antiaging 1992-1994
✦IND approved by the FDA and Phase l Clinical Trials demonstrated efficacy and
safety -no adverse side effects were observed in humans and the drug is effective
without irritation
✦Because of the dramatic safety profile the IND was withdrawn from the FDA and
MDI 101 was launched as a cosmetic in 2006
✦MDI 101 first marketed as a cosmetic on QVC television in 2006
Concert Anti-Acne
✦First developed as a topical drug for dermatology under FDA approved IND
45,548
✦ MDI 101 was designed, synthesized, and tested in 1986
✦Preclinical Studies proved efficacy and safety in photo damage repair and antiaging 1992-1994
✦IND approved by the FDA and Phase l Clinical Trials demonstrated efficacy and
safety -no adverse side effects were observed in humans and the drug is
effective without irritation
✦Because of the dramatic safety profile the IND was withdrawn from the FDA
and MDI 101 was launched as a cosmetic in 2006
✦MDI 101 first marketed as a cosmetic on QVC television in 2006
Available Formulations
✦Concert LLC has the expertise and resources to formulate MDI 101 as a
cosmetic for any type of skin
✦Formulations available include products for people with oily, normal, and dry
skin
✦Elegant and cosmetically acceptable formulations are available from Concert,
LLC
Concert Pipeline
With 30 years of successful experience designing safe molecules for specific
activity, the CONCERT molecule inventors never stop creating new
compounds. This is an ongoing process.
Three new composition-of-matter patented compounds are in the CONCERT
pipeline. They show activity in acne and anti-aging models and are being
pushed through the pipeline. They are available now for partnering or later
for sale.
CONCERT signed an agreement with a company that has a new and
proprietary molecule delivery system. This system coupled with CONCERT’s
unique compounds will provide new patented products for licensing or sale.