Transcript Alzheimer`s Disease

Alzheimer’s
Disease
By: Chelcy Branon
Facts
 In
2006, there were 26.6 million sufferers
worldwide
 Costs 100 billion dollars per year
2 Types of AD
 Early
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Symptoms before age 60
Much less common (5%); but gets more
severe quicker.
Runs in families and through genes.
 Late
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Onset AD:
Onset AD:
Symptoms after age 60.
Most common.
Causes of
Alzheimer’s
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Genetics
Old age
6th leading cause of death; live about 8 years
after diagnosed.
Starts in the learning part of the brain
Scientists believe that AD prevents parts of a
cell’s “factory” from running. As the damage
spreads, the cells lose their ability and eventually
die off.
Plaques and tangles target parts of the brain that
affect memory in people with AD.
Causes continued
 Loss
of neurons and synapses in the
cerebral cortext. Causes degeneration of
the frontal cortex, temporal lobe and
parietal lobe.
 Protein misfolding disease caused by the
over abundance of abnromally folded
amyloid beta and amyloid tau.
Medicine/Treatment
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Slow down the progression of the disease.
Manage all symptoms to make everyday life more
manageable.
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Drug Treatment:
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Donepezil and Rivastigmine: Cholinesterase inhibitor that
improves mental function. It is a naturally occuring
substance in the brain.
Galantamine: Acetylcholinesterase inhibitor that targets
memory and thought by increasing a natural substance
in the brain.
Memantine: a NMDA receptor antagonist that
decreases the abnormal activity in the brain to help
people think clearer.
Future
 95%
of known information
of AD has been found in
the last 15 years.
 Studies are continuously
happening.
 FIND A CURE.
Cites
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Board, A.D.A.M. Editorial. "Alzheimer's Disease." Alzheimer's Disease.
U.S. National Library of Medicine, 26 Sept. 2011. Web. 27 Nov. 2012.
<http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0001767/>.
"Alzheimer's Disease & Dementia | Alzheimer's Association."
Alzheimer's Disease & Dementia | Alzheimer's Association.
Alzheimer's Association, n.d. Web. 27 Nov. 2012.
<http://www.alz.org/alzheimers_disease_what_is_alzheimers.asp>.
"Alzheimer's Disease." Wikipedia; The Free Encyclopedia. N.p., 27
Nov. 2012. Web. 27 Nov. 2012.
<http://en.wikipedia.org/wiki/Alzheimer%27s_disease>.
"Alzheimer's Disease Fact Sheet." National Institute on Aging.
Alzheimer's Disease Education and Referral Center, Sept. 2012.
Web. 27 Nov. 2012.
<http://www.nia.nih.gov/alzheimers/publication/alzheimersdisease-fact-sheet>.