Transcript Meet Our Team - UCLA Medical Simulation Center

How to Supply Your Drug Habit
Creating Simulated Pharmaceuticals from
Laboratory Supplies
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Meet Our Team
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Cory Soto, B.S.,
CPhT
Simulation Specialist
Daniel Noji, B.S.
Programmer Analyst
Simulation Specialist
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Jamie Stiner
Simulation Operations Manager
Simulation Specialist
Rukhsana Khan,
M.P.H.
Simulation Specialist
Jeffrey Rusheen,
M.D.
Assistant Professor
Anesthesiology
Disclosure(s)
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
We have nothing to disclose.

Commercial vendors mentioned in this
presentation are merely used as examples.
We do not receive any compensation from
them.
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Learning Objectives
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
Create a needs assessment to tailor the
pharmaceutical production to your needs.

Demonstrate how to produce vials for use as
simulated drugs with hands-on instruction.

Find ways to implement this new tool into your
simulation center.
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Does your Simulation Center…
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
Use expired drugs?

Buy commercially available simulated drugs?

Make your own?
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The Problems
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A Solution: Do It Yourself!
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Get The Right Tools for the Job
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Outside Diameter, or
O.D.
Syringe
Borosilicate Vial
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0.9% NaCl (Normal Saline)
Table Salt
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Get The Right Tools for the Job
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Stopper
Flip-Off Cap Crimper
Flip-Off Cap
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Step One: Filling and Sealing
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Step Two: Capping
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Wow, That Was Easy!
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Step Three: Crimping
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The Assembled Vial
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Now You Get To Do It!
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Step Four: Labeling
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Meet SOPHIE
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
Simulated Online Pharmaceutical Image Editor

No need for expensive image editing suites

Developed by the UCLA Simulation Center for
use by other Simulation Centers at no cost
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What Does Your Center Need to Maintain Their Drug Habit?
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Common/Crash
Cart Meds
Medications
for Rare Conditions
(Dantrolene for Malignant
Hyperthermia, Blood Factors, etc.)
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Needs Assessment
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

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
Do you see a need for simulated medications to
enhance realism and learning during the
scenarios?
Are there any injectable drugs you would like
specifically created for your simulations? (If so,
please include concentration and volume)
Do you have any suggestions for injectable drugs
that may be useful for simulation, in general? (If
so, please include concentration and volume)
Do you know of any colleagues who would be
interested in pharmaceutical simulation or
integrating simulated pharmaceuticals into their
teaching at the Simulation Center? If so, please
provide their name and I will contact them.
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Simulated Drugs Currently Available at UCLA
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Adenosine
Amiodarone
Atropine
Calcium chloride
Dexamethasone
Digoxin immune fab
Diltiazem
Diphenhydramine
Famotidine
Flumazenil
Furosemide
Glucagon
Glycopyrrolate
Heparin
Hydralazine
Insulin
Midazolam
Naloxone
Neostigmine
Nitroglycrin
Norepinephrine
Phenylephrine
Propofol
Rocuronium
Dopamine
Esmolol
Etomidate
Labetalol
Magnesium sulfate
Metoclopramine
Succinylcholine
Vasopressin
Verapamil
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The Cost of Production
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Material Cost
Vials
Cost
2 mL
$362.78
5 mL
$213.80
10 mL
$292.20
20 mL
$297.89
Subtotal $1,166.67
Stoppers
13 mm
$77.62
20 mm
$120.65
Subtotal $198.27
Flip-Off Caps
13 mm
$82.24
20 mm
$121.27
Subtotal $203.51
Contents
0.9% NaCl
$5.05
Salt
$7.99
Labels
Glossy Laser
$19.97
Toner Cartridge
$306.34
Subtotal $326.31
Crimpers
13 mm
$152.00
20 mm
$152.00
Subtotal $304.00
Syringes
60 cc
$112.51
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Total
$2,316.32
Units
1440
864
864
720
Price Per Unit
$0.25
$0.25
$0.34
$0.41
1000
1000
$0.08
$0.12
1000
1000
Labor Cost for 500 Vials
Sim Tech Sim Tech Non-Tech Non-Tech
Hours Per Hour Cost
Per Hour
Cost
Ordering
3
$20.00
$60.00
$14.00
$42.00
Production
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$20.00
$400.00
$14.00
$280.00
Integration
3
$20.00
$60.00
$14.00
$42.00
Total
$520.00
Total
$364.00
$0.08
$0.12
Labor Cost Per Vial
3000 mL
4 lbs.
$0.002
$0.02
100
1
$0.01
$0.01
1
1
$152.00
$152.00
125
$0.90008
Sim Tech
$1.40
Non-Sim Tech
$0.73
Material Cost Per Vial
2 mL
$0.45
5 mL
$0.53
10 mL
$0.63
20 mL
$0.73
Cost Per Vial
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Vial Type Total Material Cost Simulation Tech Labor
2 mL
$0.45
$1.40
5 mL
$0.53
$1.40
10 mL
$0.63
$1.40
20 mL
$0.73
$1.40
Non-Sim Tech Labor
$0.73
$0.73
$0.73
$0.73
Vial Type Commercial Cost Tech Produced Vial Non-Tech Produced Vial
2 mL
$1.32
$1.85
$1.18
5 mL
$1.50
$1.93
$1.26
10 mL
$1.74
$2.03
$1.36
20 mL
$2.75
$2.13
$1.46
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Cost Analysis
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Total Yearly Cost Using In-House Simulated Drugs versus Commercial Drugs for
Anesthesia Residents
Vial Type
2 mL
5 mL
10 mL
20 mL
Total
Vials Produced
100
50
75
25
500
Commercial Cost
$132.00
$75.00
$130.50
$68.75
$406.25
Tech Produced
$185.00
$96.50
$152.25
$53.25
$487.00
Non-Tech Produced
$118.00
$63.00
$102.00
$36.50
$319.50
Assumption: A year’s worth of simulated drugs for Anesthesia residents is based upon 3 vials of simulated drugs used during
each simulated case, 3 cases per week, 4 times per month, 12 months per year, which equals a total of 432 vials (with an
additional 68 vials as a buffer in case more are needed throughout the year)
Total Yearly Cost Using In-House Simulated Drugs versus Commercial Drugs for
a Class of 60 Nursing Students
Vial Type Vials Produced Commercial Cost
10 mL
720
$1,252.80
Sim Produced Non-Tech Produced
$1,461.60
$979.20
Assumption: A nursing program with 60 students learning how to draw medications for intravenous administration. Each get three
10 mL vials of 0.9% NaCl to do this with. Each course occurring 4 times per year.
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References
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1.
2.
3.
4.
5.
6.
7.
Samosky J, Mikulis B, Bregman, R, Nelson, D: A Novel Intravenous Drug
Recognition System for Medical Simulators Based on Direct Fluid
Identification. Society for Simulation in Healthcare Scientific Abstract
Guide 2012; 12: 941
Steadman RH, Coates WC, Huang YM, Matevosian R, Larmon BR,
McCullough L, Ariel D: Simulation-based training is superior to problembased learning for the acquisition of critical assessment and management
skills. Critical Care Medicine 2006; 34:151-7
Rodgers D, Securro, Jr S, Pauley RD: The Effect of High-Fidelity
Simulation on Educational Outcomes in an Advanced Cardiovascular Life
Support Course. Simulation in Healthcare 2009, 4: 200-6
Qayumi K, Donn S, Zheng B, Young L, Dutton J, Adamack M, Bowles R,
Cheng A: British Columbia Interprofessional Model for Simulation-Based
Education in Health Care. Simulation in Healthcare 2012; 7:295-307
Struys MMRF, De Smet T, Mortier EP: Simulated Drug Administration: An
Emerging Tool for Teaching Clinical Pharmacology During Anesthesiology
Training. Clinical Pharmacology & Therapeutics-Nature 2008; 84: 170-4
Kimble Chase Life Science and Research Products LLC. Web site.
http://labglass.kimble-chase.com/category/serum-vials&bc=100.
Accessed March 18, 2013.
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How to Reach Us
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
Any questions or comments regarding the
material presented can be directed to the
team at:

E-mail: [email protected]

Visit our website at: www.sim.ucla.edu
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Thank You for Attending
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Questions?
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