Transcript Anti-malaria drug combination

KINGDOM OF CAMBODIA
Ministry of Health
CNM
National Center for Parasitology, Entomology and Malaria Control
National anti-malaria drug policy
Create and maintain access to early
diagnosis and prompt, effective, safe
and good quality treatment of malaria
disease.
Minimize selection pressure for drug
resistance.
Parasitological cure to reduce reservoir
of infection.
The anti-malaria drug use was based on
the National treatment guideline for
Malaria and recommended by WHO.
Anti-malaria drug combination
National Treatment Guideline for Malaria
National treatment Guideline was developed in
2000 (for combination therapy)
-
- Artesunate and Mefloquine combination for first line
treatment
- Quinine with Tetracycline for second line treatment
Anti-malaria drug procurement
Plan
MoH procurement (National budget and
WB)
CNM procurement (Global Fund)
A+M blister packaging Facility
Packaging facility was agreed by MoH to
setting up this facility
The blister packaging process was
supported by WHO and supervised by
CNM (National Malaria Center)
Artesuante and Mefloquine free tablets
were supplied by MoH (CMS) to the
packaging facility
A+Ms Categories
There are 3 categories of A+M:
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A+M2 = 6 tablets of Artesunate and 2
tablets of Mefloquine
A+M3 = 9 tablets of Artesunate and 3
tablets of Mefloquine
A+M4 = 12 tablets of Artesunate and 4
tablets of Mefloquine
Quality Assurance
Before packaging
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All of batch number of Artesunate were analyzed
All of batch number of Mefloquine were analyzed
After packaging
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All of lot number of each A+M categories were
analyzed
Stability of all A+M categories were done
At the field
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2 sides were selected for collecting the A+M
3 monthly for collecting the A+M from all fields
Anti-malaria drug supply system
The A+Ms were supplied through the
public sector
The Malarine® were supplied through the
PSI organization to the Private sector
ANTI-MALARIA DRUG SUPLLY
SYSTEM IN CAMBODIA
MINISTRY OF HEALTH
DEPARTMENT OF
DRUG AND FOOD
CENTRAL MEDICAL STORE
ESSENTIAL MEDICINE BUREAU
NATIONAL HOSPITAL=7NHs
PROVINCIAL HEALTH DEPARTMENT
OPERATIOAN DISTRICT = 75ODs
OFFICE AND PHARMACY
REFERRAL HOSPITAL
68RHs
REPORT
SUPPLY
REPORT and SUPPLY
TEMPORERY TIME
HEALTH CENTER
827HCs
Outreach Activity
HEALTH POST
Anti-Malaria drug monitoring
Drug regulation
Efficient procurement
Efficient distribution
Drug efficacy
Drug quality
Drug use practices