Transcript Grzegorz Raniszewski

Institute of Mechatronics and Information Systems
GRZEGORZ RANISZEWSKI
RADIO FREQUENCY (RF)
FOR CANCER KILLING
RADIO FREQUENCY (RF) FOR CANCER KILLING
Nanotechnology
Cancer
RF
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
CARBON NANOTUBES IN CANCER FIGHTING
Drug
delivery
Cell
destroying
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
CARBON NANOTUBES IN CANCER FIGHTING
The particles themselves can
serve as means of physical
therapy, for example, by
converting external radiation
(radiofrequency,) into heat for
thermal ablation.
Nanoparticles penetrate the
cellular membrane and deploy
different, synergistic therapeutic
agents into the cytoplasm or
other subcellular targets.
THE SIZE DOES MATTER
10 000 CNT’s
hair 10-5 m
CNT 10-9 m
10 CNT’s
virus 10-8 m
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
ENCAPSULATION OF METAL
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
INSERTION OF CNTS
- Directly to the tumor
- Bloodstream
- Aerosol inhalers
- Sublingual absorption
- Mucosal absorption
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
RF INDUCED HYPERTHERMIA
Non-invasive RF cancer treatment is an
experimental method of cancer treatment
that employs a carbon nanoparticles with
metal and radio waves to heat and destroy
cancer cells while ignoring healthy cells.

Eddy currents

Hysteresis loss
RF FIELD GENERATOR
Frequency of several MHz
Power of 600 – 800 W
Time of irradiation 1 – 2 min
RF Transmitter
Tx
Rx
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
RF Receiver
RF-INDUCED HYPERTHERMIA
Temperature of 43°C
Difficulties dissipating
the heat
Dehydration
Protein denaturation
Destruction of
the cell membrane
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
Induced
cell apoptosis
CARBON NANOTUBES AS A DRUG CARRIER
Artwork by IFE students:
A. Olejnik, M. Sobieraj, E. Ewertowska, J. Walczak, M. Kostrzewski
SINGLE-WALL CARBON NANOTUBE NANOBOMB
AGENTS FOR KILLING CANCER CELLS
Artwork by IFE students:
J. Kurzawski, A. Laska, A. Matuszek, M. Rutkowski, M.Wojciechowska
A TASK OF THE SUBJECT:
A task of the subject is to investigate the
external RF field generator for destroying
cancer cells.
Carbon nanotubes serve as a carrier for
metal atoms (iron) that are direct RF
enhancers.
This can be done by physical modelling.
This can be done by computer simulation.
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
EPS PROJECT
- The team will be introduced to the
nanotechnology and biotechnology
- The team will be supplied with package of
materials
- The team will have access to modern
laboratory and unique devices
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
EPS PROJECT
The team may include students from a
variety of specializations:
- mechanical,
- computer science,
- electronic engineering,
- electrical engineering,
- biotechnology
- and more…more…more…
JOIN THE CANCER FIGHTING CLUB!!!
Grzegorz Raniszewski
Technical University of Lodz
The Faculty of Electrical, Electronic, Computer and Control Engineering
Institute of Mechatronics and Information Systems
[email protected]
CANCER DISEASE TREATMENT METHODS
- CNTs can be connected with AmB
(Amphoreticin B) - one of the most effective
antimycotic molecules
- SWNTs with a carborane cage can be used for
boron capture therapy
- conjugation CNTs with methotrexate (MTX) - a
well known anticancer molecule
Grzegorz Raniszewski – Radio requency (RF) for cancer killing
CANCER DISEASE TREATMENT METHODS
- SWNTs with folic acid are taken up by cancer
cells which were then destroyed by a laser
wavelength of 808nm
- Carbon nanohorns can be used to encapsulate
dexamethasone and cisplatin - chemotherapy
drugs
Grzegorz Raniszewski – Radio requency (RF) for cancer killing