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Prescription Drug Abuse &
Suicide
SAVING GENERATION RX:
PREVENTING PRESCRIPTION DRUG ABUSE IN EAST
TENNESSEE
SEPTEMBER 19TH, 2014
SAMANTHA NADLER, B.S.
TENNESSEE SUICIDE PREVENTION NETWORK
Facts About Suicide
39,518 people died by suicide in 2011 in the United States.
938 people died by suicide in 2011 in Tennessee.
Approximately 317,305 people had thoughts of suicide in Tennessee in
2011 (5% of population).
Over 1 million people attempt suicide each year, according to a
recent SAMHSA study.
CDC/AFSP/AAS
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Facts About Suicide
Suicide was the 10th leading cause of death for all age groups
(2011).
Suicide was the 2nd leading cause of death of ages 10-24.
Someone dies by suicide approximately every 13.3 minutes.
Someone aged 10-24 dies by suicide approximately every 1.75
hours.
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CDC/AAS
ESTIMATES ON ATTEMPTS
25 attempts for each
documented death
Gender and Suicide - 2011
Men are nearly 4 times more likely to die by suicide than women.
Women attempt suicide 3 times as often as men.
Gender Deaths Rate
♂
♀
31,003 20.2
8,515
5.6
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MEANS OF SUICIDE - 2011
Tennessee United States
Firearms
64.9%
50.6%
Suffocation
18.6%
25.1%
Poisoning
12.9%
16.6%
All other means (cutting, jumping, etc.) are < 2%
Poisoning includes …
Overdose
Rx, OTC, & Street Drugs
Alcohol
Frequently Multiple Substances
Ingestion
of poisonous
compounds
Exposure to toxic fumes, etc.
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Overdoses
Up
8
to 75-90% of all intentional poisoning deaths
are by drugs or alcohol in the U.S.
At the same time, another study reports that
the average fatality rate for overdose is
estimated to be only 1.8%.
It is frequently challenging to separate
intentional from accidental .
Poisoning Deaths vs.
Motor Vehicle Traffic Deaths
In 2008, poisoning deaths exceeded MVT
deaths for the first times since at least 1980.
Poisoning
MVTs
deaths nearly tripled
are decreasing
Poisoning
deaths caused by drugs increased from
60% to 90%.
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Drug Poisoning Death Rates,
by Intent - USA, 1999-2009
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Facts About Suicide
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People
with substance abuse (SA) disorders
are at elevated risk for suicidal ideation and
attempts.
People
who have been treated for SA at 10
times greater risk to eventually die by
suicide than the general population.
Kelller, Borges, & Walters 1999
Prescription Drugs
Dependency & Suicide Risk
People dependent on certain kinds of
medications are at increased to die by
suicide as the general population:
Opioid
Painkillers
= 14 times the risk
Morphine,
Hydrocodone,
Oxycodone
Benzodiazepines
Ativan,
= 45 times the risk
Xanax, Librium, Klonopin,
Valium, Dalmane, Restoril, Halcion
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Substance Abuse & Suicide
~30 percent of deaths by suicide
involved alcohol intoxication –
Blood
Alcohol Content (BAC) at or
above legal limit (.08%)
~ 40-66 percent of people who die by
suicide have a positive BAC
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The Triple Dynamics of Substance
Abuse and Suicide
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- RISK FACTOR for suicide
2 - ACUTE Substance Use (Getting drunk or
high)
Decreased
fear – (FEAR is protective)
Pain, “Screwing it up!” , Disfigurement
Decreased impulse control
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– MEANS of Death
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Prescription Drugs & Suicide
Rx
abuse Risk factor
Iatrogenic factor
Means of suicide
“Risk Factors” for Suicide are
…
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Characteristics of a person that
make
it more likely that individuals will
consider, attempt, or die by
suicide.
Major Risk Factors for Suicide
Psychiatric disorder, esp. Mood Disorders
90%
of the people who die by suicide
have a mental health diagnosis.
Substance –related Disorders
Co-Occurring
Disorders
Prior suicidal behavior
Access to lethal means
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Abuse of Prescription Drugs
Significant
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risk factor
“Abuse"
is any use of a prescription drug
except as prescribed by a physician to treat
a medical condition.
Using
a higher doses than prescribed
Using
the medications of others,
Buy
Etc.
prescription drugs off the street
Iatrogenic factor
…“of a medical disorder caused by the diagnosis, manner, or
treatment of a physician.”
…“doctor caused sickness”
Examples:
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Getting an infection at the hospital.
Adverse reactions to a medication.
Doctor allows the natural history of a disease to progress untreated.
Medications Have Been
“Linked” to Depression
and/or Suicide
Anti-Depressant Medications - SSRIs
Pain Killers
Opioid Analgesics
Anticonvulsants
Inteferon/Ribavirin Therapy
Etc.
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Selective Serotonin Reuptake
Inhibitors (SSRI)
Prozac, Paxil, Lexapro, Luvox, Zoloft, etc.
Treatment for depression & anxiety disorders
2004 – FDA reviewed clinical trials with kids
“Black Box Warning”
Significant reduction in treatment for children.
Very unclear whether SSRIs affect adult suicidality
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Selective Serotonin Reuptake
Inhibitors
Later research only a small increase in suicidal risks
with SSRIs, but a much greater benefit to taking the
medication.
Depression carries it’s own risk for suicide.
Sadly, many who could have benefitted from treatment
did not get the treatment they needed.
Risk-benefit analysis needed.
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Prescription Drugs as Means
of Suicide
75% of poisoning by alcohol and/or drug overdose
47% had no known substance abuse problem
~ 25% ingested two or more drugs.
~ 8% = ETOH & Rxs
~ 8% = OTC & Rxs
~ 69% Used 1 type of Drug
~ 6% Unknown
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Suicide with Single Type
Substance Overdose
Prescription drugs = 79% of deaths due to drugs
Opioid (morphine, hydrocodone, oxycodone)
Benzodiazepines (Valium, Xanax, Librium, Klonipin)
Antidepressants (SSRIs, Tricyclics)
Over-the-counter = 10% (especially Acetaminophen)
Street drugs = 2%
ETOH = 1%
Other specified substances = 6 %
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Take Action!!!
Participate in TSPN
Monthly meetings all over the state
Regional Resource Directories
Get training – It’s Free
Suicide Prevention
Postvention
Keep doing what you are doing
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Are there any
questions?
This project is funded under27
an agreement with the State
Of Tennessee.
Contact Information
Tennessee Suicide Prevention Network
295 Plus Park Blvd., Ste. 201
Nashville TN 37217
615-297-1077–main line 615-269-5413-fax
Scott Ridgway, M.S.
Executive Director
[email protected]
Samantha Nadler, B.S.
Middle Tennessee Regional Coordinator
[email protected]
Vladimir Enlow, M.T.S.
Executive Assistant
[email protected]
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