Transcript Dambrova_InnovaBalt_04.09

Strengthening the research and innovative capacities
of the Latvian Institute of Organic Synthesis, the
leading Baltic regional centre for drug discovery
Dr. Pharm. Maija Dambrova, Manager
• Project acronym: InnovaBalt
• Type of funding scheme: Coordination
and support actions
• Work programme topics addressed:
REGPOT-2012-2013-1
• Total cost: 5.2 million euro
• Contribution of EC: 4.7 million euro
Strategic objective of the project
• to strengthen the multidisciplinary
research capacities, management of
intellectual property as well as human
resources in the innovative drug
discovery at Latvian Institute of Organic
Synthesis
Short term objectives of the project:
• Establishment and strengthening the long-lasting scientific
collaboration and strategic partnership between LIOS and
outstanding research institutions in ERA
• Increasing the innovation and improving of management of
intellectual property through collaboration and attraction of external
professionals
• Upgrading the research infrastructure at LIOS to promote the
capacity for the high level research on innovative drug development;
• Increasing the visibility of LIOS in ERA
• Ensuring the synergy between research on innovative drug
development and end-users (SMEs, industry, clinics, patients’
organizations)
• Reinforcing the strategic development of LIOS to improve the
response to socio-economic needs of Baltic region in health area
Strategic partnering organizations
Centre de RMN à Très Hauts Champs, Ecole Normale Supérieure
de Lyon
France
Institute of Biotechnology, Vilnius University
Lithuania
Tartu University
Estonia
University of Antwerp, Antwerp Drug Discovery Network
Belgium
RWTH Aachen University
Germany
Uppsala University
Sweden
Aalto University
Finland
University of Florence
Italy
Leiden University
The Netherlands
Eurice Ltd
Germany
University of Zurich
Switzerland
Scientific Steering Committee
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Representative from Latvian Ministry of Education and Science
Professor Raimonds Valters from Latvian Academy of Sciences
Dr. Andis Slaitas, managing director of Syntagon Baltic
Professor Ari Koskinen from Aalto University, Finland
Professor Daumantas Matulis from the Institute of
Biotechnology, Lithuania
Professor Ad IJzerman from Leiden University, the Netherlands
Professor Claudiu Supuran from University of Florence, Italy
Dr. Eriks Kupce Bruker Biospin, UK
Professor Edvards Liepinsh from LIOS
Professor Gunars Duburs from LIOS
Action plan of InnovaBalt project
Cardio
vascular
diseases
Cancer
Diabetes
and obesity
Neuro
degenerative
diseases
Infectious
diseases
Multidisciplinarity: chemical synthesis, molecular modelling,
pharmacological activities,targeted drug delivery forms, green chemistry
Advanced IP management and protection, innovation capacity building
Training of young and experienced researchers
Collaboration with stakeholders (policy makers, SMEs, industry, universities,
hospitals, patient organizations, society)
Integration in European research area to contribute in the solution of current
socio-economical needs in health area
Organizational structure
EC
WP8 Management
Project manager
Maija Dambrova
WP1
A.Sobolevs
WP2
L.Ignatovich
Project coordinator
Ivars Kalvins
WP3
O.Pugovics
WP4
P.Trapencieris
EU Partners
Steering Committee for
Research Strategy
WP5
D.Tirzite
WP6
I.Kalvins
WP7
G.Veinbergs
Work packages
• WP1. Exchange of experience and know-how (via international
two-way secondments of experienced and young researchers of
LIOS with researchers from excellent and complementary European
research centres)
• WP2. Strengthening of the research potential of human resources
• WP3. Renewal of research equipment
• WP4. Organization of seminars and conferences
• WP5. Improving the management of Intellectual Property and
enhancement of innovation potential
• WP6. Dissemination and promotional activities
• WP7. External Assessment of LIOS
• WP8. Management
WP1 Exchange of experience and
know-how
WP1 leader: Dr. chem. Arkadij Sobolev
Task leaders: Dr.chem. Kristaps Jaudzems,
Dr. pharm. Edgars Liepiņš, Dr. chem. Aiva Plotniece,
Dr. pharm. Maija Dambrova
Exchange of know-how and experience
via international two-way secondments
of experienced scientists and young scientists
between the LIOS and leading scientific
institutions in the ERA
– to explore the opportunities for building of lasting
networks
– to gain the access to complementary equipment, data
observations and ideas.
WP2 Strengthening of the research
potential of human resources
WP2 leader Dr.hab,chem. Lubova Ignatovich
Objectives:
• To increase the LIOS research capacity and experience
in new directions of drug discovery by recruitment of
experienced researchers
• To increase the international-level transfer process of
accumulated knowledge and technologies through the
reintegration of experienced researchers from abroad
• To increase the research potential of existing laboratories
by recruitment of post-doctoral researchers
The project foresees the recruitment of 8 experienced
researchers and 6 post-doctoral researchers
WP3 Renewal of research equipment
WP3 leader: Dr.chem. Osvalds Pugovičs
Task leaders: Dr.chem. Kristaps Jaudzems, Dr. pharm. Edgars Liepiņš,
Dr. chem. Aiva Plotniece
Objectives :
1. Acquisition of modern
equipment and tools
necessary for innovative
drug development
2. Upgrading the research
equipment
WP 4 Organization of conferences,
seminars, trainings
WP leader Dr. Chem. Pēteris Trapencieris
Task leaders: Dr. Aiva Plotniece, Dr. Maija Dambrova, Dr. Arkādijs
Soboļevs, Dr. Kristaps Jaudzems, Dr. Raivis Žalubovskis, Dr.
Osvalds Pugovičs, Ieva Jaunzeme
Objectives:
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To facilitate the knowledge transfer at the national, regional and
international levels
To increase the visibility of LIOS by dissemination of the results
of Latvian scientists in organic chemistry, medicinal chemistry of
heterocycles, structure-activity relationships, experimental
chemotherapy and pharmacology to the international scientific
community.
To strengthen the long-lasting scientific collaboration between
LIOS and partnering organisations in ERA.
WP4 Events
• Workshop “Ready for Horizon 2020” (Winter 2013/2014)
• Seminar “Advanced antiinfective drug design” (Spring 2014)
• Workshop on publication writing for scientific journals and on
popular science (Autumn 2013)
• Seminar „Biophysical methods in drug discovery” (Spring 2014)
• Seminar „Protein production techniques” (Spring 2014)
• BOS-2014 pre-conference roundtable (June 2014)
• Workshop „Competitive proposal preparation for Horizon 2020”
(Autumn 2014)
• Gustavs Vanags memorial conference ( Autumn 2014)
• Conference “BaltDrug” (May 2015)
• Conference “Paul Walden 9th Symposium” ( Autumn 2015)
• BOS-2016 pre-conference roundtable (June 2016)
• BOS-2016 conference (June 2016)
• Participation of LIOS researchers in transnational events
WP5 Improving the management of Intellectual
Property and enhancement of innovation potential
WP leader Prof.I.Kalvins
The strategy of this WP is based on 3 principles:
• development – by providing the strategic Intellectual Property
development plan for the effective management of IPR and efficient
technology transfer process
• collaboration –with governmental institutions, research, academia,
industry, technology transfer centres and other stakeholders on the
issues of innovation and IPR; by networking with partnering
organizations
• awareness – by training and education of experienced and early
stage researchers as well as entrepreneurs on the IPR and technology
transfer issues
WP6 Dissemination and promotional
activities
WP leader Dr. Biol.Dace Tirzīte
Team: Edīte Mētere, Dr. Antons Ļebedevs, Dr. Aigars
Jirgensons, Dr. Raivis Žalubovskis, Dr. Ronalds Zemribo
Objectives:
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Promotion of InnovaBalt within the scientific community
of Europe
Dissemination of information on advanced innovative
medicine development to the industry sector and other
stakeholders
Providing the information for society on topicalities in
innovative drug development and results of InnovaBalt
WP8 Assessment of research and
innovative potential of LIOS
WP leader Dr.chem Grigorijs Veinberg
The evaluation of LIOS’ overall research quality
and capability by high-level independent
experts, nominated by European Commission.
The evaluation will give essential contribution in
the definition of the further Strategic plan to
strengthen LIOS research and innovation
capacities essential for the regional economical
and social development as well as promoting
the integration of LIOS in the ERA activities.
WP7 Management of project
WP leader Dr.pharm Maija Dambrova
Management board: financial director of LIOS Dace Karkle
Dr. Edgars Suna, Dr. A. Jirgensons, Dr. Edgars Liepinsh
Objectives:
• Setting up the appropriate monitoring,
coordination and communication
procedures in order to ensure that project is
implemented in a timely and cost effective
manner in accordance with applicable EC
guidelines and national legislation rules
• Ensuring that EC financial and administrative
procedures are respected and reports and
cost statements are provided in time
Overall organization
WP8
Project
Management
T8.1 Network management
structure procedures
WP1
Exchange of
experience
and know-how
WP2
Reinforcing
human potential
T2.1 Recruitment
of experienced
researchers
T1.1 Staff
exchange planning
T1.2 Implementation
of outgoing visits
T8.3 Project technical
co-ordination and
quality policies
T8.2 Administrative and
financial management
WP3
Renewal of
research
equipment
T3.1 Ccomputer
cluster
WP4
Organization
of seminars and
conferences
T4.1 Organization
of conferences
T3.2 Crystallization
robot
T2.2 post-doctoral
researchers
T3.3 Zetasizer
Nano
T4.2
Participation in
conferences
T5.1 Recruitment
of experienced
IP manager
T5.2 Development
of IP policy
T3.4 New imaging
Technologies
T1.3 Implementation
of incoming visits
WP5
Improving the
management
of IP and
enhancement
of innovation
potential
T5.3 Staff exchange
and training
WP6
Dissemination and promotional activities
T6.1 Elaboration of
dissemination strategy
T6.2 Exploitation
of InnovaBalt
results
T6.3 Providing
Information to
industry and SMEs
WP7
Assessment of LIOS
T7.1 Kick-off
meeting of the
Experts group
T7.1 Communication
and interaction
with Expert group
T7.3 Evaluation report
and recommendations
for Strategic Plan
InnovaBalt
the leading centre for drug discovery
in Baltic region
T7.4 Workshop
on evaluation
results
Measure
Impact on innovation
•Increasing the possibilities to use contemporary
methods in the research and technology
Upgrading of LIOS infrastructure
development;
•Possibility to use upgraded infrastructure to regional
research and industry community.
•Increasing the innovation capacity;
Recruitment researchers experienced
•Organization of optimal environment for technology
in technology transfer issues
transfer and innovation.
•Strengthening the technology transfer unit;
Recruitment of specialist in Intellectual
•Providing the optimal management of Intellectual
property management issues
Property, including rights.
Staff echange in the area of
•Obtaining the best experience in innovation and
knowledge transfer and IP issues
technology transfer issues
Elaboration of Strategic Intellectual
•Providing the optimal exploitation of existing
Property development plan for LIOS
innovation capacity of LIOS.
Trainings on Intellectual property
•Increasing the capacity of regional research and
management issues
industry institutions on protection of Intellectual
Property, including rights.
Networking with industry (joint
research, activities, dissemination of
•Providing the long-lasting capacity of innovation.
knowledge, exploitation of results)
•Providing the knowledge on topicalities in the area
Conferences, workshops, seminars
of innovative medicine discovery.
The main strategic impacts
• Contribution to the research, technology and innovation
capacity building in Baltic region:
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by strengthening human capacity
improvement of technology environment and
management of intellectual property
promotion of collaboration between research centres
facilitating of cooperation with industry.
• Strong integration in ERA: through long-lasting partnership with
selected European research centres
• Improved participation in FP Horizon 2020 and other European
research programmes’ activities:
– increasing the skills and awareness about the preparation of competitive proposals
and
– improving the management skills
– networking with other research centres and industry
– establishing new partnerships.
Future expectations
• The implementation of InnovaBalt project will result in 1.5 times
increase in number of SCI publications co-authored by LOSI
personnel and 1.2 times increase in number of registered
international patents
• Reinforced IPR culture is expected to facilitate the
collaboration with business sector and improve the score of
Latvia and Baltic region in the Global Innovatin index.
• LIOS will become the distinguished centre of research and
innovation in the Baltic region in the field of medicinal
chemistry and pharmacology and will provide the contribution
in the solving of socio-economic needs of European society.
Thank you for
attention!
Paldies par
uzmanību!