Transcript suman_organic

What to study in organic
chemistry?



General organic chemistry(Ref:Peter Sykes)
Electrophiles & Nucleophiles:
Which type of systems act as E+ or Nu-?
Same system act as E+ or Nu- depending on
which system it reacts.
Acidity and Basicity:
General idea of order of acidity and basicity.
Bronsted & Lewis theory.
Effect of back-bonding , aromaticity, SIR,etc.





Funda is conjugate acid or conjugate base as
the case may be if stable then that base or acid
is strong.
Solvent and its role in reaction mechanism.
Inductive effect, Hyperconjugation, Resonance.
Aromaticity.
Tautomerism (keto-enol)
Keto-Enol Ratio – Various factors like relief of
angle strain.
Solvent & Temp. Effect on Keto-Enol Ratio

H-Bonding:
Some cases for which gemdiol is stable.
Nu- of ions in protic and aprotic solvent.
Effect of H-Bond on acidity,basicity,B.P.
Order,H-Bonding during tautomerism.
Organic Intermdiates
Carbanion:--(a)Grignard’s Reagent
1.
Preparartion
2.
As a Base & Nucleophile.
3.
Abnormal behaviour of Grignard.
4.
Iodoform reaction.
5.
WITTIG Reaction(Vinyl Ether Hydrolysis).
6.
Decarboxylation.
7.
Heating Effect of other compounds.
8.
Dry distillation
9.
Perkin Reaction

`(b) Free Radical
1.
2.
3.
Sources of free radical
Wurtz & Kolbey Electrolytic Method.
Halogenation of Alkane
©Carbene
Reactions:
1.
Riemer Teimann
2.
carbylamine
3.
Arndt Eistert
4.
Hoffmann,Schmidt,Curtius
Aromatic Chemistry

1.
2.
3.
4.
Ref: I.L.Finar (Problems and solution chp 20 to
30)
Electrophilic Aromatic
Substitution(Nitration,Halogenation,Friedel
Craft Alkylation,Freidel Craft Acylation,Kolbey
Schmidt Reaction,sulphonation)
Diazo Coupling
Cannizarro(V.V.I.)
Benzoin Condensation,Benzil-Benzilic Acid
Rearrangement
5. Phenol Chemistry:--
Preparation:-- Imp.(Cumene Process,Diazo
Method)

Claisen Rearrangement.

Sulphonation of Phenol

Dienone Phenol Rearrangement

Identification Of Phenol

Ortho Para Ratio
Other imp. Name reactions:
aldol
Cannizaro
beckmann
knovelgen condensation
hell-volhard zelinsky
reformatsky

Practical Organic Chemistry



Lassaigne Test
Test For functional group(Amines, Amides,
Substituted Amides, Nitro, Cyanide,
Isocyanide,Imine, Nitroso)
Separation of mixtures
Preparation and reactions of :
1.Aldehyde & ketone
2.Carboxylic acids
3.Hydrocarbons
4.Amines
5.Alcohols

Try to identify the link between chapters .
That can be achieved by knowing method of
interconversion.
Conversion should be properly done with the sole
purpose of getting maximum yield of product.
In Roadmap problems clue of the solution should
be identified.it is generally advisable in such
problems to start from the end.
Practising will bring about the knowledge of
reagents to be used.Understanding
mechanism& electron movement will lead to
know intermediates in a reaction(v.v.I.)
