Transcript Progress Report - Futaste Xylose Mother Liquors

Commercial Opportunities
Biomass to Renewable Chemicals
National Conference
October 3, 2012
Contact:
[email protected]
© Green Biologics Inc. 2012
Private and Confidential
Chemical Markets: Global Growth
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Fundamental shift in production
economics of petrochemicals
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Volatile oil markets
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Shale gas cracking
Strong global demand for
renewable chemicals
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Supply side economics
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Reduced carbon footprint
Long term shift in production
infrastructure
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Feedstock / crude sugars driven
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Chemical Market Drivers
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Macro trends drive renewable
alternatives
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Low carbon footprint
Consumer products that are “Green”
Technology improvements &
collaborations drive renewables
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Pretreatment / Sustainable sugar
Fermentation
Biocatalysts
Co-product recovery
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Chemicals: Market Opportunities
• Global renewable chemicals market is
estimated to reach $76.16 billion in 2015*
• CAGR of 12.67% from 2010 to 2015*
• U.S. is the second largest segment, growing at
an estimated CAGR of 5.1% to reach $17.5
billion by 2014*
• Products include alcohols, organic chemicals,
ketones, polymers, and others
• Used for industrial, transportation, textiles, food
safety, environment, communication, housing,
recreation, health and other applications
*MarketsandMarkets, 2011
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Chemicals: Performance and Economics Required
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Must be effective and
economical as conventional
materials
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Renewable is the
differentiation point
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Challenge is to close
the gap
According to Lux Research: “Today’s $1 billion biopolymer
market to see double-digit growth in the coming years.”
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Chemicals: Market Opportunities
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Chemicals: Market Opportunities
EERE_Top Value Added
Chemicals from Biomass
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Flexible Feedstocks: Projected U.S. Biomass Use
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Range of Product Opportunities
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Butanol: High Value Market Today
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Derived from petroleum today
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A direct substitute to petroleum
derived butanol
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Competitively priced without
subsidy
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$5bn butanol chemicals market
Used for paints, coatings, resins,
polymers, and solvents
$50bn biofuels market, growing at
7.5% pa
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A fermentation platform: Clostridium
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Anaerobic organism can be optimized to tolerate oxygen
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Transformation of commercially proven organisms
Fast growth compared to other anaerobes
Wide range of substrates(C5, C6, starch, etc.)
Range of product opportunities
Ability to grow in simple inexpensive media
Stability in regard to strain degeneration which offers a
solid commercial platform
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Case Study: Green Biologics Inc.
© Green Biologics Inc. 2012
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Green Biologics History
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Merger between butylfuel™ and Green Biologics (2011), creating a
global leader in production of renewable n-butanol by fermentation
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GBL - UK based biotechnology company, VC backed, founded in
2003, focused on technology development and optimization
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GBI - North America subsidiary focused on designing, owning, and
operating commercial projects
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Global team with proven commercial and technical expertise
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Projects underway at pilot, demonstration and commercial scale
Focus on $5bn chemical market with transition to $50bn biofuel
market
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GB’s Leadership in Commercializing Renewable n-Butanol
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Advanced technology
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Feedstock flexible
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Opportunities for multiple products
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Ease of implementation
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Low competition in growing markets
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Advanced Technology: Transforming Established Science
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The Clostridial ABE process was
developed in Britain in early 20th
century by Chaim Weizmann, later
the first president of Israel
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Large and growing global industry
until the 40s when oil prices dropped
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Still used commercially in Russia and
South Africa until the 1980s
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A well-understood reliable process
Fermenters in Toronto ABE plant, 1917
Picture courtesy of City of Toronto archives
Petroleum-derived butanol became
cheaper and production ceased
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South African ABE plant, circa 1950
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Solventogenic Clostridium Species – attractive producers
• Clostridia used in commercial
scale manufacture for 100 years.
• Robust
• Large substrate range (C5 & C6;
oligomers and polymers)
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Non pathogenic or toxic
New strains are aerotolerant.
New strains not readily sporulate.
Produce acetone, butanol,
ethanol, and H2 from sugars &
starches
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Advanced Technology: New Developments
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Extensive microbial culture collection
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Gram-positive bacterium, spore forming rod, non pathogenic/toxic
Produces ABE and H2
>130 strains from South Africa, environmental & culture collections
• Superior strains developed (>400 proprietary strains)
• Proprietary enzymes
• Advanced fermentation process
• Strong IP protection
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GB’s Intellectual Property
• Technology assets (microbial culture collection)
• Patents (core IP)
• Know how (methods/skills/expertise)
Feedstock
Hydrolysis
Strain
Development
Pretreatment
Hydrolysis
Genetic
manipulation
Culture
Collection
Chemical
mutagenesis
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Process
Development
bar
code
Superior
Microbes
Design &
Engineering
Gas
recovery
control
Advanced
Fermentation
Retrofit
Water
recycle
New
Build
BEST™ Product
recovery
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Advanced Technology: Flexible Bioprocessing
Feedstocks
Hydrolysis
Fermentation & Solvent Recovery
Products
Molasses
H2
hydrogen capture
Glycerine
Hemicellulose
Corn Starch
Continuous
seed
Acetone
Butanol
Saccharification
Advanced
Fermentation
Ethanol
Hydrolysis
BioJet
Bagasse
Pre - treatment
Hydrogen
Corn stover
Butyric
Acid
BEST™
Advanced Solvent Recovery
Wheat straw
Existing Technology
Under Development
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High value
chemicals
C4 platform
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Fed-batch & Continuous Fermentation
• Fed-batch, with BEST™ product
removal, doubles solvent titres
• Currently undergoing pilot scale
demonstration
• To be deployed for bolt-on
• Continuous culture with BEST™
technology shown at high
productivities (>1g/L/hr)
• Bench scale complete, pilotscale demonstration Q4 2012
• To be deployed for “bolt on”
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Ease of Implementation
• Large library of robust commercial production strains
• Tolerate oxygen & diverse feedstock inhibitors
• Stable & solvent production does not degenerate
• Low by-products
• High butanol: solvent ratios (>80%)
• Extremely low ethanol (<2%)
• Broad substrate range
• Fermentation of C5 sugars allows superior performance
• Wide range of monomers & dimers, cellulosic sugars
• Low nutritional requirements
• Fast fermentation (complete 36-48hrs: high productivity)
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Reducing enzyme costs
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Clostridia have much wider
substrate range than yeast
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Produce solvents readily
from C5 and C6 sugars,
sugar alcohols, sugar
oligomers and even some
polymers (starch, xylan,
pectin)
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Some solventogenic strains
have cellulolytic genes.
Expressing these in high
producing strains
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Clostridia likely able to utilize
biomass feedstocks with lower
enzyme loads and different enzyme
mixtures
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The C5 difference
Complements of
Dr. David Jones
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Flexible Feedstocks: Biomass Opportunities
Sugar cane $300/t sugar
Corn –
$300-500/t
sugar
Ethanol - $800/t
Butanol - $1800/t
Relatively high-priced feedstocks fermented into relatively low value products
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Flexible Feedstocks: Biomass Opportunities
Sugar cane $300/t sugar
Corn –
$300-500/t
sugar
Ethanol - $800/t
Bagasse$150/t sugar
Ag Res./ MSW
$50-150/t sugar
Butanol - $1800/t
GB enables producers to ferment low value feedstocks into high value products
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Flexible Feedstocks
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Typical Cellulosic Composition
Use of C5 sugars key to
superior performance
C6 Sugars
C5 Sugars
GB’s organisms can utilize
diverse cellulosic feedstocks
Molasses benchmark
Corn stover Hardwood pulp enzymatic cellulosic hemicellulose
hydrolysis
fraction
35%
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37%
Sugar cane bagasse
Sorted
Municipal Solid
Waste
39%
35%
36%
39%
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Unique Positioning: Parallel Technology Demonstration
Fast track approach allows timely commercialization
Pilot
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Demonstration
Commercial
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North American Opportunities for Deployment
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Leverage ethanol industry/assets
• 217 ethanol plants (working/shut down)
• Ethanol to integrated biorefinery
• Bolt-on and retrofit distressed assets
• JV investment opportunities
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Opportunities with existing sugar plants
• Sugar / energy beets and molasses
Multiple bolt-on opportunities
• Sweet sorghum and energy sorghum
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Leverage pulp & cellulosic industry/assets
• Bolt-on and retrofit distressed assets
2012 Top 10 Prediction:
“Ethanol producers begin
switch to biobutanol and
chemicals en masse”
• JV investment opportunities
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North America Biorefinery Options
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Bolt On to Existing Ethanol Asset
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Ease of deployment
Value added to existing asset
Transformation to a biorefining complex
Phase 2 Addition of Cellulose conversion
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Fermentation Including both C5 and C6 sugars
Proven on wide range of cellulosic feedstocks
Ability to operate on cellulose or original bolt on corn mash
Evolutionary biorefining with corn or cellulose feed
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Ethanol Bolt-On Opportunity Utilizing Cellulosic Feedstocks
Biomass Receiving
and storage
Cellulose Scope Phase 2
Pretreat to
monomer sugars
GBL Fermentation
GBL Solids &
Evaporation
Butanol & Acetone
Ethanol
GBL Distillation
GBL Butanol
storage & loadout
Protein solids to DDGS
Thin Stillage
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Bolt on Scope Phase 1
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Oxo-Chemicals (C4) Platform
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Butanol – a Product of Choice
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Market size ($5bn chemical market, $50bn biofuels market)
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Flexibility of feedstock and end product opportunities
Fast global market growth for renewable n-butanol
Proven technology (pilot to commercial scale)
Profitability (ethanol $800/t versus butanol $1800/t)
Opportunity for a range of low capital solutions (bolt-on or
repurpose)
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Summary: Commercializing Renewable n-Butanol
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Attractive markets
• 10 billion lbs. chemical market, biofuel opportunities
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GB’s technology leadership
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World leader in ABE fermentation technology
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Extensive microbial culture collection
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Advanced fermentation process
• Multiple feedstock and product opportunities
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C5 & C6 sugars
Proven on wide range of cellulosic feedstock
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Attractive implementation options
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Process engineering designs for “bolt on” & retrofit
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Demonstrated technology
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Enables high return, low Capex solutions
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Know-how from working across global customer base
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Effective & Economical in growing markets
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Biologics
Inc.
2012
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Inc.
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Questions
Contact:
[email protected]
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Inc.
2012
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2012
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