Transcript Distributed System of Thyroid Gland Monitoring for Population

National Taras Shevchenko
University of Kyiv
Medical Radiophysics Department
SII «Intermag»
Distributed System of Thyroid Gland
Monitoring for Population Suffered from
Chernobyl Accident
M. Kononov, S. Radchenko, V. Ruditsa, O. Sudakov
© Sergiy Radchenko 2006
General architecture of thyroid
gland monitoring system
Database
Server
Telemedical
Server
Network
Work place
Work place
……...
Work place
Physician work places
• General information about patient state;
• Inquirer based screening examination;
• Thyroid gland ultrasonic scanning;
• Hormone testing;
• Biopsy.
Database table types
• Data tables — data of the forms;
• Auxiliary tables — information to
reproduce the real view of the forms from
the rows of data table.
Work place for ultrasound scanning
Form for ultrasound scanning data
Form editor
General distribution of data on to nosologies.
nodular goiter
10%
chronic
thyroiditis
24%
combined
goiter
12%
thyreotoxicosis
3%
norma
29%
goiter
14%
hypothyrosis
8%
Scatterers set with random parameters
S
 a
S
 a
S
S
S
S
 a
 a
 a
 a
s t    a n exp  i n 
N
n 1
f  A,  
r r r r r r
Echo-signal forming by the
system of scatterers with
random parameters.
( is incident wave,  is
scattered field component,
i is phases of scattered waves,
ri is coordinate of scatterer
location,
ai is wave amplitude,
S i is scatterer size).
 
 Am
b
M
b  bA 
   M 1 ba  U  A
 M   2 
m

 M  
m
m
2
2 
 
 
  1  
M 
 2 b
2 M  0.5 1.5
M  A


M  2 r4  2
r2i



EA 
E A 2i
2
i
Evaluation of thyroxine concentration
arb. un.
40
38
36
34
M, відн. од.
32
30
28
26
24
Тіреоїдит
Thyroiditis
Norma
норма
22
20
18
16
14
12
40
60
80
100
120
140
К, нмоль/л
109 M l
160
180
200
220
Segmentation of medical images
Polychromic reconstruction of medical images

LR  f P1  x , y 


LG  f P2  x , y 
Reconstruction

LB  f P3  x , y 



Colour mixing.
Scheme of polychromic reconstruction
of medical images.
Polychromic reconstruction of ultrasound images
Norma
Thyreotoxicosis
Chronic thyroiditis
Resume and prospect
• The client-server architecture with specialized protocol an
described structure of information streams provide stability work of
monitoring and safety of teleconsultative system.
• Developed methods of data synchronization and commands
passing on the server provide effective work even on slow
channels and connection breakages.
• Test results of information transfer protocols and telemedical
system server showed high stability of system work and possibility
of its applying in clinics.
• Clinic proceeding of thyroid gland pathology in irradiated persons
exposed to ionizing irradiation is of peculiar scientific-practical
interestafter in 20 years. The first place among diseases takes
thyroiditis with gradual evolution into hypothyreosis. The increase
of nodal goitre frequency should also be noted.
• Diagnostic availabilities of ultrasound investigation of thyroid gland
increase under complex estimation of echogram changes along
with studying the stage of decrease of echogeneity and
echostructural heterogeneity based on physical models of
scattering.
Acknowledgement
• The part of this work is funded by STCU
(project NN 40).
• www.rpd.univ.kiev.ua/departments/med/
• www.intermag.kiev.ua