Transcript Peptic Ulcer

Peptic Ulcer
By: Alex and Arjun
What is Peptic Ulcer Disease?
Open sores in the digestive tract
Two types
Gastric ulcers
Forms in lining of stomach
Duodenal ulcers
Forms in lining of duodenum (upper part of small intestine)
Causes
Caused by
the bacteria H. pylori and Aspirin or NSAIDS(Non steroidal anti inflammatory drugs)
they secrete urease which breaks down mucus membrane
the area that lacks the mucus membrane is damaged by gastric acid
It is a myth that stress and spicy foods can cause Peptic Ulcers, but they can
aggravate
symptoms
H. pylori has many flagella that it
uses to propel itself
Occurs more in elderly people
Diagram
Peptic ulcers usually occur in the
lower gastric or upper duodenal
region.
Symptoms of Peptic Ulcer
Some patients may not show symptoms
However common symptoms include:
Burning pain in the abdominal region
Vomiting
Appetite change
Bleeding in stomach/duodenum
Weight loss
Treatment
The outside of the
pill dissolves in the
stomach and the
alkaline contents
inside neutralizes
stomach acid
Antibiotic that kills H. pylori
Medications that block acid production
Antacids that neutralize stomach acids
Refraining from smoking and alcohol
medications called cytoprotective agents can help protect the tissues that line
your stomach and small intestine
Statistics
In the United States, about 10% of the population will develop a duodenal ulcer at some point in their
lives.
Peptic ulcer disease affects about 4.6 million people annually.
The occurrence of peptic ulcer disease is similar in men and women, but men are slightly more likely
to get a peptic ulcer. Approximately 11%-14% of men and 8%-11% of women will develop peptic
ulcer disease in their lifetime.
The mortality rate of peptic ulcer disease is approximately one death per 10,000 cases. The mortality
rate due to ulcer hemorrhage is approximately 5%.
References
http://www.mayoclinic.org/diseases-conditions/pepticulcer/basics/definition/CON-20028643?p=1
https://www.nlm.nih.gov/medlineplus/pepticulcer.html#summary
http://www.emedicinehealth.com/peptic_ulcers/article_em.htm
http://www.skinsheen.com/userfiles/files/Symptoms%20of%20Peptic%20Ulc
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