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PowerPoint® Lecture Slides
prepared by Leslie Hendon,
University of Alabama,
Birmingham
22
HUMAN
ANATOMY
PART 2
The Digestive
System
fifth edition
MARIEB | MALLATT | WILHELM
Copyright © 2008 Pearson Education, Inc.,
publishing as Benjamin Cummings
Histology of the Alimentary Canal Wall
Same four layers from esophagus to anus
The mucosa – innermost layer
Consists of
Epithelium
Lamina propria
Muscularis mucosae
The submucosa – external to the mucosa
Contains blood and lymphatic vessels, nerve fibers
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Histology of the Alimentary Canal Wall
The muscularis externa – external to the
submucosa
Two layers
Circular muscularis – inner layer
Longitudinal muscularis – outer layer
The serosa – the outermost layer
Is the visceral peritoneum
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Histology of the Alimentary Canal
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.5
Smooth Muscle
Primarily found in walls of viscera
Fibers elongated
Have one centrally-located nucleus
Grouped into sheets
Longitudinal layer – parallel to long axis of organ
Circular layer – deeper layer, fibers run around
circumference of organ
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Smooth Muscle
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Figure 22.6a, b
Smooth Muscle Contraction
Myofilaments
operate by
interaction with
cytoskeleton
Dense bodies –
correspond to Zdiscs of skeletal
muscle
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.7a–c
Innervation of Smooth Muscle
Innervated by ANS
Few fibers per sheet innervated
Sheet of smooth muscle contracts as a unit
Exceptions
Iris of eye
Arrector pili muscles in skin
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Innervation of Smooth Muscle
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.8
Nerve Plexuses
Myenteric nerve plexus
Lies between circular and longitudinal muscularis
Controls peristalsis and segmentation
Submucosal nerve plexus
Lies in submucosa
Signals glands to secrete
Innervation
Sympathetic and parasympathetic motor fibers
Visceral sensory fibers
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
The Peritoneal Cavity and Peritoneum
Peritoneum – a serous membrane
Visceral peritoneum – surrounds digestive organs
Parietal peritoneum – lines the body wall
Peritoneal cavity – a slit-like potential space
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
The Peritoneal Cavity and Peritoneum
Mesentery – a double
layer of peritoneum
Holds organs in place
Sites of fat storage
Provides a route for
circulatory vessels and
nerves
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.9a
The Peritoneal Cavity and Peritoneum
Retroperitoneal organs
Behind the peritoneum
Peritoneal organs
Digestive organs that
keep their mesentery
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.9b
Mesenteries
Superficial view of abdominal organs
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.10a
Mesenteries
Lesser omentum attaches to lesser curvature of
stomach
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.10b
Mesenteries
Greater omentum –
a “fatty apron” of
peritoneum
Greater omentum and
transverse colon
reflected
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Figure 22.10c
Mesenteries
Sagittal section through
the abdominopelvic
cavity
Mesenteries attach to
posterior abdominal
wall
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Figure 22.10d
Secondarily Retroperitoneal Organs
Initially formed within peritoneum
Become retroperitoneal
Fuse to posterior abdominal wall
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Figure 22.11
Summary of Intraperitoneal and
Secondarily Retroperitoneal Organs
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Table 22.1
The Mouth and Associated Organs
The mouth – oral cavity
Mucosal layer
Stratified squamous epithelium
Lamina propria
The lips and cheeks
Formed from orbicularis oris and buccinator
muscles, respectively
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Anatomy of the Mouth
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Figure 22.12a
Anatomy of the Mouth
The labial frenulum
Connects lips to gum
The palate
Forms the roof of the
mouth
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.12b
The Tongue
Interlacing fascicles of skeletal muscle
Grips food and repositions it
Helps form some consonants
Intrinsic muscles – within the tongue
Extrinsic muscles – external to the tongue
Lingual frenulum
Secures tongue to floor of mouth
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
The Superior Surface of the Tongue
Tongue papillae
Filiform papillae – no taste buds
Fungiform papillae
Circumvallate papillae
Sulcus terminalis
Marks border between mouth and pharynx
Posterior 1/3 of tongue lies in oropharynx
Lined with lingual tonsil
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Superior Surface of the Tongue
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Figure 22.13
The Teeth
Deciduous teeth – 20 teeth
First appear at 6 months of age
Permanent teeth – 32 teeth
Most erupt by the end of adolescence
Dental formula – shorthand
Way to indicate number and position of teeth
2I, 1C, 2P, 3M
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The Teeth
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Figure 22.14
Tooth Structure
Longitudinal
section of tooth in
alveolus
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Figure 22.15
The Salivary Glands
Produce saliva
Compound tubuloalveolar glands
Parotid glands
Parotid duct – parallel to zygomatic arch
Contains only serous cells
Submandibular glands
Lies along medial surface of mandible
Sublingual glands
Lies in floor of oral cavity
Contains primarily mucous cells
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The Salivary Glands
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Figure 22.16
The Pharynx
Oropharynx and laryngopharynx
Passages for air and food
Lined with stratified squamous epithelium
External muscle layer
Consists of superior, middle, and inferior pharyngeal
constrictors
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
The Esophagus
Gross anatomy – muscular tube
Begins as a continuation of the pharynx
Joins the stomach inferior to the diaphragm
Cardiac sphincter – closes lumen to prevent
stomach acid from entering esophagus
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
The Esophagus
Microscopic anatomy
Epithelium is stratified squamous epithelium
When empty – mucosa and submucosa in
longitudinal folds
Mucous glands – primarily compound
tubuloalveolar glands
Muscularis externa
Skeletal muscle first third of length
Adventitia – most external layer
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Microscopic Structure of the Esophagus
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
Figure 22.17a, b
The Stomach
Site where food is churned into chyme
Secretion of pepsin begins protein digestion
Functions under acidic conditions
Food remains in stomach approximately 4 hours
Copyright © 2008 Pearson Education, Inc., publishing as Benjamin Cummings
The Stomach
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Figure 22.18a
The Stomach
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Figure 22.18b
Microscopic Anatomy of the Stomach
Muscularis has three layers
Circular and longitudinal layers and oblique layer
Epithelium is simple columnar epithelium
Mucosa dotted with gastric pits
Gastric glands – deep to gastric pits
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Microscopic Anatomy of the Stomach
Gastric glands of fundus and body
Mucous neck cells
Secrete a special mucus
Parietal (oxyntic) cells
Secrete hydrochloric acid and gastric intrinsic factor
Chief (zymogenic) cells
Secrete pepsinogen
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The Stomach – Microscopic Anatomy
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Figure 22.19a–d
The Small Intestine – Gross Anatomy
Longest portion of the alimentary canal
Site of most enzymatic digestion and absorption
Three subdivisions
Duodenum
Jejunum
Ileum
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The Duodenum
Receives digestive enzymes and bile
Main pancreatic duct and common bile duct
enter duodenum
Sphincters control entry of bile and pancreatic
juices
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The Duodenum and Related Organs
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Figure 22.20
The Small Intestine – Microscopic Anatomy
Modifications for absorption
Circular folds (plicae circulares)
Transverse ridges of mucosa and submucosa
Villi
Finger-like projections of the mucosa
Covered with simple columnar epithelium
Microvilli
Further increase surface area for absorption
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Histology of the Intestinal Wall
Absorptive cells
Uptake digested nutrients
Goblet cells
Secrete mucus that lubricates chyme
Enteroendocrine cells
Secrete hormones
Intestinal crypts
Epithelial cells secrete intestinal juice
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The Small Intestine – Structural Features
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Figure 22.21a–d