Transcript Renal System

Formation of Urine
 Excretion or Conservation of Water
 Electrolyte Balance
 Acid-base Balance
 Activation of Vitamin D
 Production of Erythropoietin
 Production of Renin

Glomerular filtration
 Glomerular filtration rate
 Tubular reabsorption
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› Include water and electrolytes
Tubular secretion
 Urine concentration
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Renal Filtrate Kidneys form in 1 minute
 Averages 100-125 mL/minute
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Renin-angiotensin-aldosterone system
› Role in blood pressure and sodium
reabsorption
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Erythropoietin
› Role in RBC production
Vitamin D and calcium regulation
 Acid-base balance
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Ureters: carry urine from kidneys to
bladder
 Bladder: temporary storage of urine and
its elimination
 Urethra: carries urine from bladder to
exterior
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Amount: 1000-2000 mL/24 hours
 Color: straw or amber
 Clarity: clear
 Specific Gravity: 1.010-1.030
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› Lower=Dilute; Higher=Concentrated
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pH: 4.6-8.0
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Constituents
› 95% water
› Waste products: Urea, Creatinine, Uric Acid
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Renal Mass Smaller
Renal Flow Decreased 50%
Decreased Tubular Function
Bladder Muscles Weaken
Bladder Capacity Decreases
Voiding Reflex Delayed
Nephrons lost with aging
› Reduces kidney mass and GFR

Less urine concentration
› Risk for dehydration
Health History
 Pain/Burning with Voiding
 New Onset Edema, Shortness of Breath,
Weight Gain
 Fluid Intake
 Functional Ability
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Color, clarity, amount of urine
 Difficulty initiating urination or changes in
stream
 Changes in urinary pattern
 Dysuria, nocturia, hematuria, pyuria
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Vital Signs
 Lung Sounds
 Edema
 Daily Weights
 Intake and Output
 Skin Assessment
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Urinalysis
› Common test
› Voided or Cath Specimen
 24 hour
 Clean catch
› 10 mL of urine collected
› Color, odor, clarity
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Urine Culture
› Identifies bacteria present
› Urine collected before antibiotics
› Sensitivity test determines antibiotic that will
destroy bacteria
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Renal Function Tests
› Serum Creatinine
› Blood Urea Nitrogen
› Uric Acid
› Creatinine Clearance Test
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Kidneys-Ureter-Bladder
› Show tumors, swollen kidneys, kidney stones
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Intravenous Pyelogram
› Dye injected
› Dye outlines renal structures
› Check allergies
› Increase fluids afterward
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Renal Angiography
› Dye visualizes renal arteries
› Check allergies
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Cystoscopy and Pyelogram
› Surgery: Cystoscope inserted in bladder
through urethra
› Pyelogram: dye injected in kidney pelvis
› X-rays taken
Noninvasive sound waves examine
anatomy of urinary tract
 Shows kidney enlargement, kidney
stones, chronic infection, tumors
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Percutaneous or Open
 Before - NPO, Mild Sedative
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After
› Vital signs
› Observe for bleeding
 Biopsy site, Urine
› Pressure dressing, sandbag
› Bed rest for 24 hours
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Types
› Stress
› Urge
› Functional
› Overflow
› Reflex
 total
Postvoid residual urine
 Ultrasonic bladder scan
 Cystometrography
 Uroflowmetry
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Medications
› Inhibit detrusor muscle contractions
› Increase bladder capacity
› Estrogen therapy
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Surgery
› Bladder neck suspension
› Prostatectomy
Impaired Urinary Elimination
 Toileting Self-Care Deficit
 Social Isolation
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Evaluating
› Keep voiding diary
› Identify wetting episodes
› Assess willingness to participate in social
activities
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Teaching
› Home environment
› Voiding diary
› Therapies
Occurs when bladder cannot empty
 May be caused by obstructive or
functional problem
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› Benign prostatic hypertrophy
› Surgery
› Drugs
› Neurologic diseases
› Trauma
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Acute
› Anesthesia, medications, local trauma to
urinary structures
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Chronic
› Enlarged prostate, medications, strictures,
tumors
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Manifestations
› Overflow voiding
› Incontinence
› Firm, distended bladder
 May be displaced
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Monitor
› Urine output
› Bladder distention
› Bladder Scan
 Residual volume of 150-200 cc urine
 Indicates need for treatment
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Complications
› Hydronephrosis
› Acute renal failure
› Urinary tract infection
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Diagnostic tests
› Portable bladder scan
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Treatment depends on cause
› Surgery
› Medications
› Stimulation techniques
› Catheterization
Identify clients
 Take measures to promote urination
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Indwelling Catheters
› Justifiable reasons
 Shock
 Urinary tract obstruction
 Neurogenic bladder
› Urinary incontinence is NOT justification
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Urinary catheters result in infection
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Intermittent catheterization
› Best
› Reduces risk of infection
› Patients may self-cath
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Suprapubic Catheter
› Indwelling catheter inserted through incision
in lower abdomen into bladder
Invasion of urinary tract by bacteria
 Women > Men
 Aging
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› Older men due to enlarged prostate
› Women due to declining estrogen
› Nosocominal infections common
Stasis of urine
 Contamination in Perineal/Urethral area
 Instrumentation
 Reflux of urine
 Previous UTIs
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Dysuria
 Urgency
 Frequency
 Cloudy, foul-smelling urine
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Urethritis: inflammation of urethra
 Cystitis: inflammation/infection of
bladder wall
 Pyelonephritis: infection of the kidneys
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Dysuria, flank pain, fever, chills, malaise
 Urine examined for cloudiness, blood,
foul odor
 Predisposing factors
 Urinalysis and culture results
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Urinalysis
 Urine culture & sensitivity
 CBC with differential
 IP
 Voiding cystourethrography
 Cystoscopy
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Acute pain
 Impaired urinary elimination
 Risk for injury
 Knowledge deficit
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Monitor symptoms
 Monitor intake and output
 Pain control
 Teaching
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› Medications: take all antibiotics – 3-7 days
› Prevention
Obstruction of urine flow is always
significant
 Backup of urine destroys kidney
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Urethral Strictures
› Urethra lumen narrowing due to scar tissue
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Renal Calculi
› Hard, generally small stones
› Kidney stones
 Nephrolithiasis
Urolithiasis most common cause of
obstructed urine flow
 Calculi
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› Masses of crystals formed from materials
normally excreted in urine
› Most made from calcium
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Etiology
› Heredity
› Chronic dehydration
› Infection
› Immobility
› Men > Women
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Kidney/Pelvis
› May be asymptomatic
› Dull, aching flank pain
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Ureter
› Acute severe flank pain, may radiate
› Nausea/vomiting
› Pallor
› Hematuria
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Bladder
› May be asymptomatic
› Dull suprapubic pain
› Hematuria
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Diagnosis
› Kidney-ureter-bladder x-ray
› Intravenous Pyelogram (IVP)
› Renal ultrasound
› Urinalysis
Small stones passed
 IV fluids
 Pain control
 Thiazide diuretics
 Allopurinol
 Lithotripsy
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Medications
 Dietary management
 Surgery
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› Lithotripsy
› ESWL
› Cystoscopy
› Nephrolithotomy
› Nephrectomy
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Prevention
› Foods
› Hydration
› Exercise
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Complications
› UTIs
› Hydronephrosis
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Nursing Diagnosis
› Acute pain
› Risk for infection
› Deficient knowledge
Monitor symptoms
 Strain all urine
 Intake and output
 Pain control
 Hydration
 Teaching
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Abnormal dilation of renal pelvis and
calyces
 Results from urinary tract obstructions or
backflow of urine
 Manifestations depend on how rapidly it
develops
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Diagnosis
› Ultrasound
› CT scan
› Cystoscopy
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Treatment
› Stents
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Signs and symptoms
› Frequency
› Urgency
› Dysuria
› Flank and back pain
› Renal failure
Treat cause
 Urinary catheter
 Stents
 Nephrostomy tube
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› Intake and output
› No clamping
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Focuses on prevention and ensuring
urinary drainage
Most common urinary tract cancer
 Men > Women
 Ages 50-70 years
 Etiology
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› Smoking
› Industrial pollution
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Signs and symptoms
› Early
 Painless
 Hematuria
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Signs and symptoms (cont’d)
› Late
 Pelvic pain
 Lower back pain
 Dysuria
 Inability to void
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Diagnosis
› Urinalysis
 Telomerase
› Urine for Cytology, Culture
› Cystoscopy and Transurethral Biopsy
› IVP
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Therapeutic Interventions
› Chemotherapy
› Bacille Calmette-Guérin Vaccine
› Photodynamic Therapy
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Therapeutic Interventions
› Surgery
 Cystoscopy & Pyelogram with Fulguration
 Laser
 Robotic Laparoscopic Radical Cystectomy
 Urinary diversion
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Therapeutic Interventions
› Incontinent urinary diversion
 Ileal conduit
› Continent urinary diversion
 Kock pouch
› Othotopic bladder substitution
 Studer pouch
 Hemi-Kock pouch
 Ileal W-Neobladder
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Nursing Care
› WOC Nurse
› Monitor urine output
› Education
› Preop and postop care
Uncommon
Renal cell carcinoma most common
primary tumor
 Risk factors
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Smoking
Obesity
Renal calculi
Hypertension
Long term kidney dialysis
Radiation exposure
Asbestos
Industrial pollution
Most arise from tubular epithelium
 Can occur anywhere
 Often metastasize
 Often silent
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Later signs and symptoms
› Hematuria
› Dull pain in flank area
› Mass
IVP
 Cystoscopy and Pyelogram
 Ultrasound
 CT scan
 MRI
 Renal biopsy
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Therapeutic Interventions
› Radical Nephrectomy
› Nephron-sparing surgery
› Radiation therapy
› Immunotherapy
› Chemotherapy
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Nursing Management
› Monitor urine output
› Education
› Preop and postop care
Pain
 Ineffective breathing pattern
 Risk for impaired urinary elimination
 Anticipatory grieving
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Flank pain
 Hematuria
 Treat injury
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Nursing Care
› I&O
› Vital signs
› IV fluids
› Pain control
Multiple cysts in the kidney
 Signs and symptoms
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› Dull heaviness in flank/back
› Hematuria
› Hypertension
› UTI
Progressive
 No treatment
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Long-term complication of diabetes
 Most common cause of renal failure
 Atherosclerotic changes decrease blood
to kidney
 Smaller doses of insulin as progresses
 Chronic renal failure develops
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Inflammatory condition of glomerulus
 Acute or chronic
 Primary kidney disorder or secondary to
systemic disease
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Affects structure and function of
glomerulus
 Damages capillary membrane
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› Blood cells and proteins escape into filtrate
› Hematuria, Proteinuria, Azotemia
Usually follows infection of group A betahemolytic Streptococcus
 Manifestations develop abruptly
 Hematuria, proteinuria, edema,
hypertension, fatigue
 Anorexia, nausea, vomiting, headache
 Elevated BUN and serum creatinine
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Older adults may show less characteristic
manifestations
 Symptoms may subside spontaneously
 Some may develop chronic
glomerulonephritis
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Usually end-stage kidney damage
 Slow, progressive destruction of glomeruli
 Gradual loss of nephrons
 Kidneys decrease in size
 Symptoms develop slowly
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ASO titer
ESR
BUN
Serum creatinine
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Serum electrolytes
Urinalysis
KUB x-ray
Kidney scan or
biopsy
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Signs and symptoms
› Oliguria
› Hypertension
› Electrolyte imbalances
› Edema
› Flank pain
Focus is on identifying and treating
underlying disease process and
preserving kidney function
 Medications
 Plasma exchange therapy
 Dietary management
 Renal failure treatment
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Vital signs
 Symptom support
 Rest
 Fluid, sodium, protein restrictions
 Renal failure care
 Education
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Preventing acute renal failure is goal of
care
 Diagnostic tests
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› Serum creatinine, BUN
› Creatinine clearance
› Serum electrolytes, ABGs, CBC
› Urinalysis
› Kidney biopsy
Kidneys unable to remove waste
products from blood
 Acute or chronic
 Azotemia
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› Waste products accumulate
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Fluid, electrolyte, acid-base imbalances
› Oliguric
Rapid decline in function
 Abrupt onset
 Often reversible with treatment
 Risk factors
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› Major trauma, surgery, infection,
hemorrhage, severe heart failure, lower
urinary tract obstruction
› Older adults at risk
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Prerenal Failure
› Decreased blood supply to kidneys
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Intrarenal Failure
› Damage to nephrons
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Postrenal Failure
› Obstruction
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Nephrotoxins
› Diagnostic Contrast Media (Dyes)
› Medications
 IV Aminoglycosides, Tobramycin (Tobrex),
Amikacin (Amikin), Cisplatin (Platinol)
› Chemicals
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Prevention
› Check serum BUN and creatinine prior to
dyes or meds
› Hydrate before/after contrast media
› Monitor peak/trough levels of nephrotoxic
drugs per institutional policy
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Phases
› Oliguric
› Diuretic
› Recovery
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Therapeutic Interventions
› Treat cause
› Supportive treatment
› Dialysis
› Continuous renal replacement therapy
Removes fluid continuously along with
Hemodialysis
 Remove fluid/solutes in controlled,
continuous manner in unstable patients
 Blood flows through Hemofilter, excess
fluids/solutes move into collection bag

Gradual decrease in kidney function
 Irreversible
 Slow, insidious process
 Final stage is end-stage renal disease
 Increasing in incidence
 Diabetic nephropathy and hypertension
leading causes in U.S.
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Etiology
› Diabetic Nephropathy
› Nephrosclerosis
› Glomerulonephritis
› Autoimmune diseases
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Nephrons destroyed by disease process
Remaining nephrons hypertrophy and have
increased workload
› Can compensate for a while
Renal insufficiency develops – 75% of
nephrons lost
 Further insult leads to ESRD
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› Uremia develops
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End-stage: 90% of nephrons lost
Uremia: urea in the blood
Affects all body systems
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Often not identified until uremia
develops
› Nausea
› Apathy
› Weakness
› Fatigue
› Confusion
Fluid accumulation
 Electrolyte imbalance
 Waste products retained
 Acid-base imbalance
 Anemia
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Diet
› High calorie
› Low protein (unless dialysis)
› Low sodium, potassium, phosphorus
› Increased calcium
› Vitamins

Fluid restrictions
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Medications
› Diuretics
› Antihypertensives
› Phosphate binders
› Calcium/Vitamin D supplements
› Kayexalate prn

Dialysis
› Symptoms of fluid overload
› High potassium
› Neurological signs
› Uremia

Hemodialysis
› Artificial kidney removes waste products and
excess water from blood
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Vascular Access
› Temporary
› LifeSite Hemodialysis Access System
› A-V Graft
› A-V Fistula
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Vascular Access Care
› Thrill, Bruit
› Protect
› Postop
 NV checks, pain
 Elevate extremity
Continuous dialysis done by patient
 Peritoneal membrane is semipermeable
membrane, across which excess
wastes/fluids move from blood
 Peritoneal catheter
 Exchange process: fill, dwell time, drain

Excess fluid volume
 Imbalanced nutrition: less than body
requirements
 Risk for infection
 Disturbed body image
 Activity intolerance
 Impaired skin integrity
 Risk for injury


Excess fluid volume
› Monitor weight
› I&O
› Fluid restriction
› Monitor for fluid retention

Electrolyte imbalance
› Monitor levels
› Dietary restriction
› Monitor dysrhythmias

Waste products
› Oral care, skin care
› Lotion
› Protect from injury

Impaired hematological function
› Protect from injury/infection
BPH tends to occur in men over 40 years
of age
 Intervention is required when symptoms
of obstruction occur
 The most common treatment is
transuretheral resection (TURP)
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PSA
› False high levels can be present for up to 12
days after a rectal examination or
instrumentation around the prostate gland
especially after a cystoscopy

Signs and symptoms
› Increased frequency with a decrease in
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amount of each voiding
Nocturia
Hesitancy
Terminal dribbling
Decrease in size and force of stream
Acute urinary retention
Bladder distention
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TURP
› Preop teaching
› Monitor urinary drainage system
› Provide pain relief
› Monitor urinary drainage system for clots
› Irrigate bladder as prescribed
› Monitor H &H
› Monitor v/s
Hematuria generally is present for at
least 23 hours following a TURP
 Monitor color & content of urinary output
 Care post catheter removal
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› Monitor # of voids and amount
› Have client collect urine in specimen cups
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Force fluids