Addiction to Alcohol and Other Drugs
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Transcript Addiction to Alcohol and Other Drugs
Chemical Addictions—General
Overview
Abdullahi Mubarak, MD
Medical Director of Addiction
Services at PEMCO
Chief Medical Officer at
Consortium Clinical Services,
LLC
Objectives
Understand general terminology
The disease of Addiction
Symptoms of the disease
Stages of change
Diagnostic tips
General treatment approaches
Terminology
Use—drug taking not associated with harm
Abuse—drug taking associated with harm
Dependence—adaptation to drug evidenced
by normal functioning and/or withdrawal
syndrome
Addiction—loss of control, compulsion,
continued use despite adverse consequences
Terminology
Abuse potential—the likelihood that a
person will abuse a drug based upon it’s
pleasurable effects, toxicity, and society’s
attitude toward the users of the drug
Addiction potential—the likelihood that a
drug will produce addiction in chronic users
Relative Addiction Potential
Cocaine (crack, IV, snorted, chewed)
Methamphetamine (smoked)
Nicotine (IV, smoked, chewed)
Opiates (IV, smoked, snorted, chewed, oral)
Alcohol
Sedative-hypnotics
Anabolic steroids
Marijuana
Inhalants
PCP, other hallucinogens (LSD, Special K, )
Disease of Addiction
Addiction is primarily a function of many
genetically predisposed biological
responses.
The response and/or lack of the drug
reinforces the repeated use of the drug.
The environment permits and facilitates the
use of the drug.
Addiction can be “created” in low risk
patients with chronic use of drugs of high
addictive potential.
Progression of the Disease
Erratic drug-taking pattern, erratic sleep,
work, eating, grooming, and social habits
New forms of enjoyment, new “friends”,
ways of relating, isolation, hiding money,
hiding whereabouts, lying
Legal, financial, marital, social, career, and
lastly physical adverse consequences
Stages of Change
Pre-contemplation—lacks awareness
Contemplation—ambivalent about change
Preparation—getting information in order to
change
Action—actually committing to sobriety in deed
Maintenance—attaining stability
Recovery—sobriety
Relapse—use leads to return to contemplation
Signs of Aberrant behavior
Prescription forgery
Concurrent abuse of illicit drugs
Selling prescriptions
Recurrent lost, stolen, or spilled drugs
Stealing or borrowing from others
Obtaining drugs from non-medical sources
Obtaining scripts from multiple doctors
Indicators of Suspicion
Reluctant to present identification
“Out of town” patient
Overly willing to pay cash
Telephone call in for controlled substances
Presents when the regular physician cannot
be reached
Indicators of Suspicion
Allergy to NSAIDS, COX-2’s, or codeine
Intolerant to collateral contacts
Intolerant to in-depth interviews
Interested only in the drug, not the
diagnosis
Reluctant to comply with diagnostic testing,
pill counts, and urine screening
Factors Less Indicative
Drug hoarding during periods of decreased
symptoms
Unsanctioned dose escalation
Request for specific drugs by name
Focus on opiate issues during the first three
office visits
Abnormal Physical Signs
Pupils < 3mm or >6.5mm in room light
Presence of nystagmus
Diminished or absent corneal and/or
pupillary light reflex
Impaired convergence
Pulse < 60 or > 100/min
Venosclerosis or needle tracks
Perforated nasal septum
Characteristics of the Pain
patient
Appreciates in-depth interviews
Cooperates with attempts to get collateral histories
Cooperates with pill counts and urine drug
screening
Focus is on the diagnosis and the cure
Attempts to reduce medications on their own
Cooperates with diagnostic and therapeutic
interventions
Addressing Aberrancy and
indicators of suspicion
Obtain an INSPECT report
Urine drug screen (UDS)
Use oral salivary testing when urine
screening is unavailable, patient unable to
void, or the UDS is invalid
Pill counts when appropriate
Use Axis V outline to clarify your thoughts
Treat ONLY according to your diagnosis
INSPECT reports
The report is unconfirmed history until you
confirm what’s in it.
“Multiple prescribers” means nothing until
you call the providers to find out what they
did, why they did it, and did they know
there were other prescribers
Keep the interpretation of the report in your
chart
Urine drug screening
The results only mean what the results say
Using them to make a diagnosis is only part of the
total picture
Refer for addiction consultation, if the results are
aberrant
Negative screens can mean abuse, addiction,
diversion, or pseudo-addiction syndrome
Do not collect without temperature strips on the
cup.
Be sure the reference lab tests for validity and
multiple metabolites
Oral Salivary Testing
Easy to use, less intrusive
Shorter window of detection compared to
urine drug screening
Accuracy comparable to blood testing
The results only mean what the result says
Pill Counts
Best when used sparingly or unexpected
Best to clarify negative urine drug screens
Order within 2 days to rule out diversion
Order within 10 days to rule out abuse or
addiction
Pills can be brought to office or the pharmacy they
purchased their pills
Record any markings on the pills for identification
Diagnostic Challenges
Impaired by lack of knowledge of differential
diagnosis
Impaired by EMOTIONAL reactions to the
“names” of controlled substances
Use Axis V outline to highlight deficiencies in
knowledge or when you are becoming too
emotional
Say “NO”, if the request is inappropriate for the
diagnosis or you have inadequate information to
arrive at a diagnosis
Continue to monitor to confirm or deny your
provisional diagnosis. Being wrong is ok.
Consultation
Learn the biases of your consultants.
Psychiatry consultation for benzo and
stimulant prescribing for mood disorders,
ADHD, etc…
Addiction consultation to evaluate
aberrancy
Pain management consultation to evaluate
opiate prescribing
General treatment principles
Foremost goal initially is self-diagnosis
Educate—Addiction is a disorder in a
person, not the pill
Medication assistance—diminish drug
craving, withdrawal, and normalize function
Intensity of treatment related to intensity of
use pattern and/or history of treatment
failures
Strengthen social/spiritual supports