Transcript Symptoms - Ning.com

Patient
Findings Medications History
AHer
58-year-old
medications
woman
were
presented
levothyroxine,
her
A
woman
complains
A58-year-old
urine dipstick
was
positive to
forof
hydroxychloroquine,
primary
care
physician
pravastatin,
after
several
and
dizziness,
anorexia,
dry
mouth,
leukocyte esterase and nitrites. The
of dizziness,
alendronate.
anorexia,
increased
thirst,
and
frequent
patient
given
adry
Herdays
history
was
notable
for
cutaneous
Her
family
history
included
oral
mouth,
increased
thirst,
and
frequent
urination.
Shefohad
alsoosteoporosis,
had a fever.
prescription
ciprofloxacin
forand
a
lupus,
hyperlipidemia,
bladder
cancer
in
her
mother,
Graves'
urination.
She
had
also
had
a
fever
She
reported
no
pain
in
her
abdomen,
urinary
tract
infection.
3
days
later,
frequent urinary tract infections, a left
disease
in
two
sisters,
and
reported
“get
back,
and
nothat
cough,
orwould
diarrhea.
patient
reported
weakness
and
oophorectomy
for
afood
benign
cyst,
and
hemochromatosis
in
one
sister,
and
stuck”
when
she
was
swallowing.
She
dizziness.
Her supine blood
pressure
primary
hypothyroidism,
diagnosed
a
idiopathic
thrombocytopenic
purpura
reported
no mm
pain
in
her
abdomen,
back,
was 120/80
Hg,
and
pulse
was
88.
year earlier
sistershortness of
or flank andinnoone
cough,
breath, diarrhea, or dysuria
Family
History
Patient
History
Symptoms
Family
Medications
Findings
Symptoms
Putting the Pieces Together at Point of Impact
Can Be Life Changing
0
difficulty swallowing
fever
dry mouth
thirst
anorexia
frequent urination
dizziness
no abdominal pain
no back pain
no cough
no diarrhea
Oral cancer
Bladder cancer
Hemochromatosis
Purpura
Graves’ Disease
(Thyroid Autoimmune)
cutaneous lupus
osteoporosis
hyperlipidemia
frequent UTI
hypothyroidism
Alendronate
pravastatin
levothyroxine
hydroxychloroquine
urine dipstick:
leukocyte esterase
supine 120/80 mm HG
heart rate: 88 bpm
urine culture: E. Coli
Diagnosis Models
Confidence
Renal failure
UTI
Diabetes
Influenza
hypokalemia
Esophagitis
• Extract Symptoms from record
Most
Most
Confident
ConfidentDiagnosis:
Diagnosis:UTI
Diabetes
Esophagitis
Influenza
• Use paraphrasings mined from text to handle
• Identify
• •Extract
Extract
negative
Patient
Family
Medications
Symptoms
History
alternate
phrasings
and
variants
•••Use
Reason
Medical
•
Use
with
database
Taxonomies
mined
of
relations
drug
to
generalize
side-effects
to explain
medical
away
Perform broad search for possible
diagnoses
••conditions
Together,
symptoms
multiple
to
the
(thirst
granularity
diagnoses
is
consistent
used
may
by
best
w/
the
UTI)
explain
models
Score Confidence in each diagnosis based on
symptoms
evidence
so far
• Extract Findings: Confirms that UTI was present
© 2011 IBM Corporation