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Acute Hepatitis
Rachel Hart
Client Background
Teresa (Terri) Wilcox
22-year-old female
Education: Full time college
graduate student during the day
Hours of work: An exotic dancer in
the evenings to early morning
Ethnic back ground: European
American
Religious affiliation: Unitarian
Anthropometric Data
Height: 5 feet 9 inches
Current weight: 130 pounds
Usual body weight: 145 pounds
Percent usual body weight: 90%
Moderate to severe malnutrition
BMI: 19.2 kg/m2
Just within normal weight range
Patient History
Relatively good health all her life, does have seasonal
allergies, non smoker, non drug user, does drink 1-2
glasses of wine per week
Family history: hypertension, diverticulitis, cholecystitis,
diabetes, peptic ulcer disease, bilateral breast cancer,
leukemia, cirrhosis, amyotrophic lateral sclerosis
Medications:
YAZ, 1 tab po daily
Allegra, 60 mg po qd
Complains of fatigue, aches, and pains, vague right upper
quadrant pain, and nausea and anorexia
Primary Complaint
“I just feel so tired. I can hardly
move, my joints ache so much, and
my muscles feel sore.”
Physical Exam
General appearance: Tired-looking, college-aged female
Eyes: Wears contact lenses to correct myopia, PERRLA
Extremities: Normal muscle tone, normal ROM
Abdomen: Pierced umbilicus; upper right abdomen
guarding
Nutrition History
General: Appetite usually good, but has not had one in the last
few weeks
24 –hour recall showed that she had not consumed adequate
nutrition
Usual dietary intake:
Breakfast: Usually cereal and orange juice
Lunch: Takes lunch to eat on campus or gets fast food at the
Student Union
Dinner: Eats at work, usually carryout (Chinese food)
Vitamin and mineral intake:
400 mg vitamin E qd
500 mg calcium multivitamin/ mineral qd
Abnormal Chemistry
Bilirubin
Normal: ≤ 0.3 mg/dL
Terri: 1.5 mg/dL (high)
ALT (alanine aminotransferase)
Normal: 4-36 U/L
Terri: 340 U/L (high)
AST (aspartate aminotransferase)
Normal: 0-35 U/L
Terri: 500 U/L (high)
ALP (alkaline phosphatase)
Normal: 30-120 U/L
Terri: 303 U/L (high)
LDH (lactate dehydrogenase)
Normal: 208-378 U/L
Terri: 695 U/L (high)
HDL-C
Normal: >50 mg/dL
Terri: 50 mg/dL (low)
Abnormal Hematology
WBC (white blood cell)
Normal: 4.8-11.8 x
10^3/mm^3
Terri: 12.6 x 10^3/mm^3
(high)
HGB (hemoglobin)
Normal: 12-15 g/dL
Terri: 11.5 g/dL (low)
HCT (hematocrit)
Normal: 37-47 %
Terri: 36 % (low)
Platelet count
Normal: 140- 144 x
10^3/mm^3
Terri: 140 x 10^3/mm^3
(low)
PT (prothrombin time)
Normal: 11-16 sec
Terri: 17 sec (high)
Abnormal Urinalysis
Protein
Normal: NEG mg/dL
Terri: 1+ mg/dL
Diagnosis and Treatment
Diagnosis
Acute hepatitis C
Treatment
Vitamin B-complex
supplement
High-kcal, high-protein diet
Bed rest
Continued Allegra
Alternative contraception
What is Acute Hepatitis C?
Means inflammation of the liver.
Acute hepatitis C virus infection is a short-term illness that
occurs within the first 6 months after someone is exposed
to the hepatitis C virus.
For most people, acute infection leads to chronic infection.
Hepatitis A, B, C, D, E are diseases caused by five different
viruses.
Etiology
People can become infected with the hepatitis C virus
during such activities as:
Sharing needles, syringes, or other equipment to inject drugs
Needle stick injuries in health care settings
Being born to a mother who has hepatitis
Less commonly, a person can also get hepatitis C virus
through:
Sharing personal care items that may have come in contact
with another person’s blood, such as razors or toothbrushes
Having sexual contact with a person infected with the
hepatitis C virus
Symptoms
Approximately 70%–80% of people with acute hepatitis C do not have
any symptoms.
Some people, however, can have mild to severe symptoms soon after
being infected, including:
Fever
Fatigue
Muscle aches
Loss of appetite
Nausea
Vomiting
Abdominal pain
Dark urine
Clay-colored bowel movements
Joint pain
Jaundice
Diagnostic Measures
Acute hepatitis is often tested for because of the
appearance of symptoms
Blood tests:
Anti-HCV:
Looks for and measures antibodies to HCV
HCV RNA:
Qualitative test: detects the presence or absence of
HCV RNA
Quantitative test: measures the number of copies of
HCV RNA in the blood
Diagnostic Measures
Blood tests may help to:
Determine whether a person has the hepatitis C
virus
Measure the quantity of the hepatitis C virus in
the blood
Evaluate the genetic makeup of the virus, which
helps determine treatment options
Treatment
Primary medical treatments:
Regenerate liver cells and prevent and delay formation
of chronic hepatitis with drugs
3-MU interferon alfa-2b sq qd
Ribavirin (Rebetol) 200 mg po bid
Bed rest
Medical nutrition therapy
High calorie, high protein diet
Micronutrient supplementation
Medical Nutrition Therapy
Doctors usually recommend rest, adequate nutrition and fluids.
Want to avoid further damage of the liver and regenerate cells.
Consult dietitian:
Increased energy needs
30-35 kcal/kg body weight
Adequate protein
1-1.2 g/kg body weight
30-40% of kilocalories from fat
Multivitamin
Abstain from alcohol
Client Energy and Protein Needs
Kilocalorie needs:
30-35 (kcal) x 65.9 (kg)= 1,977 to 2,307 kilocalories per
kilogram of body weight per day
Range of: 2,000-2,300 kilocalories per day
Protein needs:
1-1.2 (grams) x 65.9 (kg)= 65.9-79.1 grams of protein per
kilogram of body weight per day
Range of: 66-79 grams per day
Prognosis
Out of every 100 people infected with the
Hepatitis C virus:
About 75–85 people will develop chronic
Hepatitis C virus infection; of those,
60–70 people will go on to develop chronic liver
disease
5–20 people will go on to develop cirrhosis over a
period of 20–30 years
1–5 people will die from cirrhosis or liver cancer
Questions??
References
Hepatitis C. (2102). Lab Tests Online. Retrieved from
http://labtestsonline.org/understanding/analytes/hepatitis-c/tab/test
Hepatitis C. (2102). National Institutes of Health [NIH]. Retrieved from
http://www.nlm.nih.gov/medlineplus/hepatitisc.html
Hepatitis C information for the public. (2012). Center For Disease
Control and Prevention. Retrieved from
http://www.cdc.gov/hepatitis/c/index.htm
Hepatitis C: Nutrition care. (2012). Dietitians of Canada. Retrieved
from http://ww.bccdc.ca/NR/rdonlyres/EA6145BC-FF7B-448A-B5E66EDED47D878C/0/Hep_Guidelines_HCVNutritionCare.pdf
Interferon and ribavirin treatment side effects. (2012). Department of
Veteran Affairs. Retrieved from
http://www.hepatitis.va.gov/provider/reviews/treatment-sideeffects.asp