Transcript Slide 1

Excretory System
Metabolic Waste Removal
Organs of Excretory System
 Lungs
– CO2 and water
 Skin - Sweat
 Kidneys – Urine
 Liver – detoxification of blood
 These
organs work with other body
systems to keep the body in
homeostasis.
Excretion
 Excretion
– is the process by which
waste and excess substances are
removed from the body.
 If wastes from metabolism
(metabolic wastes) are not removed
from the body, the body will die.
 Metabolic wastes come from
chemical reactions in the cells of the
human body
Major Metabolic Wastes
Carbon Dioxide
 Nitrogen compounds

– Ammonia
– Urea
– Uric acid

Mineral Salts
– Sodium chloride
– Potassium sulfate

All of these wastes are poisonous to the
body in high concentrations
Nitrogen wastes
 Nitrogen
wastes are a by product of
protein metabolism.
 Amino groups are turned into
ammonia, which in turn is converted
to urea, dumped into the blood and
filtered out by the kidneys.
 Ammonia is converted to urea, a
compound the body can tolerate at
higher concentrations than ammonia.
Role of the Liver
 Removes
harmful substances such as
bacteria, certain drugs, and
nitrogenous wastes from the blood
 In the liver the substances are
changed into inactive or less
poisonous forms
 Inactive substances (urea) are
returned to the blood stream and
filtered and excreted by the kidneys.
The Skin
 The
skin performs a number of
different functions one of them is
excretion of wastes.
 In sweat there is a small amount of
urea and salts.
 Sweat 99% water 1% Urea and Salts
Lungs
 Excrete
CO2 and Water
– The end products of cellular respiration
Urinary System
Waste is filtered from the blood and
collected as urine in each kidney.
 Urine leaves the kidneys by ureters, and
collects in the bladder.
 The bladder can distend to store urine that
eventually leaves through the urethra
 The urinary system:

–
–
–
–
Kidneys
Ureters
Bladder
urethra
Urinary tract
Kidneys
Ureters
Bladder
Urethra
Prostate
Female
Male
Kidneys
 Bean
shaped organs that are about
10cm long
 Main Functions:
– Remove wastes of cellular metabolism
(metabolic waste)
– Regulate the concentrations of the
substances in the blood
Kidneys (1)
Kidneys (2)
Structure of the Kidneys

Kidney is made up of 3 parts
– Cortex – outer part
– Medulla – middle part
– Pelvis – inner part
Blood is filtered in the cortex
 Collecting ducts extend through the
medulla
 The filtered substances, called the filtrate,
collect in the pelvis which are connected
to the ureter

Cross Section of Kidney
Nephrons
MOST important job of the kidney is
to filter waste from blood
 The filtering is done by the nephron.
 There are about 1.25 million
nephrons in each kidney

Components of The Nephron
Glomerulus:
Arteriole blood is
filtered under high
pressure.
 Bowman's
Capsule:
surrounds the
glomerulus and
collects the filtrate

Bowman capsule
Component of Nephrons Continued
Proximal
Convoluted
Tubule
 Loop of Henle
 Distal
Convoluted
Tubule

– All of these nephron
structures aid in the
reabsorption of
materials needed
for the body.
Nephron (1)
The Nephron Function
The nephron
consists of a ball of
blood capillaries
called the
glomerulus
 Blood flows into
the kidney through
the renal artery,
which branches
into capillaries
associated with the
glomerulus.

The Nephron Function Continued



Arterial pressure causes
water and solutes from
the blood to filter into the
Bowmans Capsule which
surrounds the glomerulus
The Filtrate flows through
the proximal convoluted
tubule, loop of Henle,
and then into the distal
convoluted tubule.
The distal tubule empties
into a collecting duct.
Which carries urine to the
pelvis of the Kidney
The nephron has three functions:
 Glomerular
filtration of water and
solutes from the blood.
 Tubular reabsorption of water and
conserved molecules back into the
blood.
 Excretion of urine from collecting
tubes
WOW that’s a big filter
 Nephrons
filter 125 ml of body fluid
per minute; filtering the entire
body fluid component 16 times
each day.
 In a 24 hour period nephrons
produce 180 liters of filtrate, of
which 178.5 (99%) liters are
reabsorbed.
 The remaining 1.5 liters forms urine.
Disruption of Kidney Function
 Infection,
environmental toxins such
as mercury, and genetic disease can
have devastating results by causing
disruption of kidney function. Many
kidney problems can be treated by
dialysis, where a machine acts as a
kidney. Kidney transplants are an
alternative to dialysis.