Transcript Self_Test__12_11 505.0 KB

Fast and simple way to produce a study guide
Copy any slide and alter it to develop a self test
On the slide that was copied, place shaded squares or rectangles or any
geometric figures to hide useful information. The shaded figures in row A can be
copied using Mac or PC commands that are outlined on the next slide. That next
slide shows how to make multiple of copies of a given geometric figure as shown
in row B. Now place shaded figures over parts of the copied slide to cover up
“useful” information to develop your self test.
1.Row A.
1.Row B.
2.See how this is done in examples A-E.
How do I Cut, Copy, and Paste with a Mac?
On a Mac computer, the Command key is generally located adjacent to
the spacebar and is often labeled with a ⌘ symbol that resembles a
four leaf clover. The following key combinations require that you first
press and hold the Command key, while proceeding to press the letter
assigned to the Copy, Cut or Past function.
To Copy with a Mac, use the following key combination:
Command + C
To Cut with a Mac, use the following key combination:
Command + X
To Paste with a Mac, use the following key combination:
Command + V
PC method
Actions:
Mouse method:
Mouse and keyboard
method:
Copy
Highlight, right click, copy
Highlight, Ctrl, c
Cut
Highlight, right click, cut
Highlight, Ctrl, x
Paste
Highlight, right click, paste
Highlight, Ctrl, v
Example A
Structure of an antibody molecule
A
The seven areas (A-F) of the
antibody molecules are as follows:
NH2
NH2
NH2
NH2
B
C
F
CL
COOH
CH1
CH1
CL
D= Fc region
E= Interchain disulfide bonds
-S-S-
-S-S-
COOH
CH2
CH2
F=Fab region
D
CH3
COOH
E
CH3
COOH
A= Fv region
B= Framework region
C= Complementarity
determining regions
(CDRs)
Not shown in the diagram are intrachain
disulfide bonds which are present in each
of the 12 domain of the antibody molecule
Two light chains and each with two
domains
Two heavy chains and each with four
domains
4
Self-Test
Study the unaltered slide for 30 minutes. Now take the self test with the
altered slide to see if you can remember what information on the altered
slide is hidden. To verify your response click and remove the blue shaded
rectangles and squares to see the hidden information. See the attached
powerpoint slides to allow you to do such an operation. Now return the
shaded rectangles to the same or different position on the slide for future
testing
Structure of an antibody molecule with covered sections
A
NH2
NH2
NH2
To Identify hidden
information.
Click and lift to see answers.
NH2
B
C
F
CL
COOH
CH1
CH1
CL
COOH
CH2
C= Complementarity
determining regions
(CDRs)
CH2
D
CH3
CH3
A= Fv region
B= Framework region
-S-S-
-S-S-
The shaded rectangles can be moved to cover
information on different sections of the
antibody molecule to generate new self-tests
D= Fc region
E= Interchain disulfide bonds
COOH
E
COOH
F=Fab region
6
Example B
Structure of an antibody molecule
A
NH2
NH2
NH2
In Man five different classes of
antibody molecules are present
with seven similar regions
NH2
B
C
F
A= Fv region
B= Framework region
C= Complementarity determining regions
(CDRs)
D= Fc region
E= Interchain disulfide bonds
CL
COOH
CH1
CH1
CL
F=Fab region
-S-S-
-S-S-
The five classes are easily
remembered with the word
“GAMED”
COOH
CH2
CH2
D
CH3
COOH
E
CH3
COOH
G = IgG
A = IgA
M = IgM
E = IgE
D = IgD
8
Self-Test
Study the unaltered slide for 30 minutes. Now take the self test with the
altered slide to see if you can remember what information on the altered
slide is hidden. To verify your response click and remove the blue shaded
rectangles and squares to see the hidden information. See the attached
powerpoint slides to allow you to do such an operation. Now return the
shaded rectangles to the same or different position on the slide for future
testing
Structure of an antibody molecule with hidden information
A
NH2
NH2
NH2
In Man five different classes of
antibody molecules are present
with seven similar regions
NH2
B
C
F
A= Fv region
B= Framework region
C= Complementarity determining regions
(CDRs)
D= Fc region
E= Interchain disulfide bonds
CL
COOH
CH1
CH1
CL
F=Fab region
-S-S-
-S-S-
The five classes are easily
remembered with the word
“GAMED”
COOH
CH2
CH2
D
CH3
COOH
E
CH3
COOH
G = IgG
A = IgA
M = IgM
E = IgE
D = IgD
10
Example C
Original and Not Altered
The immune system consists of organs, tissues and cells,
as well as soluble and integral membrane proteins. The
system itself can be diabolical, that is, it protects the host
from potential pathogenic agents, is important in
inflammation and in some cases initiates autoimmune
diseases and other disorders. A vital component of the
immune system are a collection of proteins that are needed
to complete antibody antigen reactions and are known as
complement proteins. In fact, the complement system
consists of classical, alternative, and lectin pathways. Each
pathway in the complement system is important in
destroying disease producing agents and in tissue repair.
However, the enzymes of the complement system must
also be controlled to prevent nonspecific damage to host
tissues and cells that can lead to disease.
Self-Test
Study the unaltered slide for 30 minutes. Now take the self test with the
altered slide to see if you can remember what information on the altered
slide is hidden. To verify your response click and remove the blue shaded
rectangles and squares to see the hidden information. See the attached
powerpoint slides to allow you to do such an operation. Now return the
shaded rectangles to the same or different position on the slide for future
testing
Altered
The immune system consists of organs, tissues and cells,
as well as soluble and integral membrane proteins. The
system itself can be diabolical, that is, it protects the host
from potential pathogenic agents, is important in
inflammation and in some cases initiates autoimmune
diseases and other disorders. A vital component of the
immune system are a collection of proteins that are needed
to complete antibody antigen reactions and are known as
complement proteins. In fact, the complement system
consists of classical, alternative, and lectin pathways. Each
pathway in the complement system is important in
destroying disease producing agents and in tissue repair.
However, the enzymes of the complement system must be
controlled to prevent nonspecific damage to host tissues
and cells that can lead to disease.