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COM Research Strategic Initiatives April 16, 2014 Where We Are – The Research $$! # Total Grant Applications 300 250 299 200 254 150 247 257 236 100 50 0 FY09* FY10 *ARRA Included FY11 FY12 FY13 Number of Awards/Yr* 180 160 140 120 100 80 60 40 20 0 112 FY09 175 108 FY10 FY11 *Includes New and Continuation 140 FY12 149 FY13 $ Value of Awards* $35,000,000 $30,000,000 $25,000,000 $20,000,000 $15,000,000 $10,000,000 $5,000,000 $0 FY09 FY10 FY11 FY12 FY13 FUNDING SOURCES NUMBER OF PIs with NIH GRANTS 70 60 50 55 40 30 57 63 FY12 FY13 50 46 20 10 0 FY09 FY10 FY11 Total Research Expenditures (Direct + Indirect) Research Expenditures (COM+S&W+VA) $40,000,000 $35,000,000 $30,000,000 Indirect $25,000,000 Direct $20,000,000 $15,000,000 $10,000,000 $5,000,000 $0 FY09 FY10 FY11 FY12 FY13 Where Do We Want to Be?? Scientific discovery of fundamental principles and mechanisms of action Clinical trials to evaluate outcome and efficacy Transform scientific discovery into clinical application “bench-to-bedside-community” COM Major Research Initiatives • Translational Science • Microbiome • Biomedical Informatics 1. Translational Science • New Department of Clinical & Translational Medicine (CTMD) • 25+ new faculty • MDs or MD/PhDs • 75-80% research/20-25% clinical duties 2. Microbiome Research • The microbiome is defined as the collective genomes of the microbes (composed of bacteria, bacteriophage, fungi, protozoa and viruses) that live inside and on the human body • It is estimated that humans harbor 1014 microbial cells and 1015 viruses, and this huge amount of non-human genetic material is referred to as our metagenome • The microbiome may influence many aspects of human health Examples of human health related to the microbiome: • Susceptibility to certain infectious diseases • Contribute to disorders such as obesity and diabetes • Contribute to the development of some chronic illnesses of the gastrointestinal system such as Crohn's disease and irritable bowel syndrome • Development of immune system • Neurological diseases – autism?? • Response to a particular drug treatment • Cancer • The maternal micriobiome may even affect the health of her children - breastfeeding 3. Biomedical Informatics (BI) • A discipline at the intersection of information science, computer science, and health care. It deals with the resources, devices, and methods required to optimize the acquisition, storage, retrieval, and use of information in health and biomedicine. • Goal: To create Biomedical Informatics Core that fosters and develops BI across TAMUS and our clinical partners • Director (Jack Smith) and first faculty in place What does Biomedical Informatics do? • Develop systems for integration of diverse data (text and image) • Develop systems of management and sharing of patient records • Data mining – retrospective vs prospective studies!!! Questions, comments, ideas!!