Transcript Mittman_Human Microbiome NYANP

Whose Vis is it Anyway?
The Human Microbiome, Health
& the Vis Medicatrix Naturae
Paul Mittman, ND, EdD
Human Microbiome
The microbiome is defined as the collective genomes of the
microbes (composed of bacteria, bacteriophage, fungi,
protozoa and viruses) that live inside and on the human body.
National Human Genome Research Institute
http://www.genome.gov/27549400
Human History of Disease Shaped
our Relationship with Microbes
Causes of Death 1900/2010
NEJM
Medicine as
Opposition to Disease
Symbiosis in
Biological Systems
Legumes
Nitrogen Fixation in Leguminous Plants
Hermann Hellriegel 1888
Symbiosis
•
Mutualism – Both Organisms Benefit
•
Commensalism – One Benefits the other unaffected
•
Parasitism – One Benefits, the other harmed
Termites, Bacteria and Protists
http://www.riken.jp/en/research/rikenresearch/highlights/6214
© 2010 Shigeharu Moriya
Termites, Bacteria and Protists
The Bacterium and the Squid
Hawaiian Bobtail Squid
Euprymna scolopes / Vibrio fischeri
Mutualism
Symbiosis in
Human Health
Plasmodium Falciparum
Helicobacter pylori
Human Microbiome
Illya Ilyich (Elie) Metchnikoff
Nobel Prize 1908
Proposed Lactobacillus Consumption
Polymerase Chain Reaction
PCR
Individual Culture
Human Microbiome
Microbial Transmission
In Utero
At Birth
Perinatal Antibiotics
Breastfeeding
Microbial contact during pregnancy, intestinal colonization and human disease
Nature Reviews Gastroenterology and Hepatology 9, 565-576 (October 2012) | doi:10.1038/nrgastro.2012.144
Microbial Transmission via Breastmilk
The human milk microbiota: origin and potential roles in health and disease.
Pharmacol Res. 2013 Mar;69(1):1-10
Human Milk Oligosaccharides
Bifidobacterium longum subspecies infantis
TMAO & Heart Dz
Genomic Phylostratigraphy
Genomic Phylostratigraphy
Questions
Whose vis is it?
Does an individual’s microbiome play a role in energetic
therapies?
Can the microbiome help explain naturopathic medicine’s
vitalistic approach to healthcare?