Transcript Healthy Trac™ Market For Digestive Health

Healthy Trac™
Market For Digestive Health
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#2 Retail Product Category ($2 Billion).
60 Million Suffer Digestive Health
Problems Each Year.
#1 Reason For Emergency Room Visits;
Responsible For 36 Million Visits a Year.
Attributes As A Functional
Food And Beverage Ingredient
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Clinically Safe Results With Humans.
Low Calorie, Fat, Sodium And No Cholesterol.
Excellent Source of Fermentable Dietary Fiber.
Low Protein And Thermostable.
Low Viscosity, High pH And Salt Compatible.
Low Sensory Impact.
Health Benefits of
Healthy Trac™
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Promotes a Healthy Environment For Long Term
Colon Health.
A Gentle Laxative For Consistent Regularity. Does Not
Promote Laxative Dependence.
A Weapon to Help Fight Cholesterol.
Helps Reduce Insulin, Carbohydrate And Blood Sugar
Levels. An Important Benefit For Diabetics.
Enhances The Immune System by Increasing Natural
Killer Cell Activity And Cellular Immune Response.
Healthy Trac™
Safety Profile
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Common Name: Larch Sugar.
Chemical Name: Arabinogalactan.
FDA Approved As A Direct Food Additive.
FEMA GRAS Listed.
DSHEA Approved (Met Pre-1994 Market
Requirement).
Structure/Function Filed FDA 1998
GRAS Self-Affirmed, FDA Consent to GRN-47 June
2000
Environmental Issues: Non-Toxic, Readily
Biodegradable And Safe.
The Effect Of Increasing
Levels of Healthy Trac™.
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1.5 Grams/Day Boosts The Immune System.
2.1 Grams/Serving (8.4 Grams/Day Total)
Lowers LDL And Total Cholesterol.
2.8 Grams/Serving Provides 10% of The Daily
Fiber Requirement.
4.0 Grams Per Day Lowers Serum Insulin And
Blood Sugar Levels. Benefit For Diabetics.
5.6 Grams/Day Provides 20% of The Daily
Requirement For Dietary Fiber.
Healthy Trac™ As
Prebiotic Fiber
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Food Source For Bifidus Bacteria.
65% Slowly Fermented to Short Chain Fatty
Acids (SCFA) At Normal Flora Growth Rates.
Butyrate Generation High (30% Of Total
SCFA).
Inhibits K88 E. coli Attachment To Gut
Epithelial Cells.
Reduces beta-glucuronidase activity.
None Of The Side Effects OF Other Fibers.
A
Short Chain Fatty Acids (SCFA)
With Health Trac™
1400
1200
1000
800
600
400
200
0
Acetate
Propionate
Butyrate
University Of Minnesota
Y2000 Clinical Study Results.
Clinical Design
 Double Blind, Placebo Controlled
 100 Human Subjects, 6 Months, Free
Living Diet
 Effects Of Daily Dietary
Supplementation On Blood Lipid,
Gastrointestional And Immune Function.
Digestive Health Results
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10 Fold Increase In Anaerobes.
100 Fold Increase In Bifidobacteria.
10 Fold Increase In Lactobacilli.
10 Fold Decrease In Enterobacters.
10 Fold Decrease In Clostridium
No Adverse Reactions Or Negative Side
Effects.
Stool Consistency Softened.
Regular Healthy Bowel Movements.
Blood Lipid And Serum
Analyte Studies.
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15 % Reduction In Total Cholesterol In
Hyperlipidemic Subjects.
5-10% Reduction In Serum Glucose
Levels.
20-25% Reduction Of Serum Insulin
Levels
Immune System Proliferation.
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Healthy Trac™ Immune Activity Is 3 Times
More Active Than The Popular Herb
Echinacea.
Has Been Shown To Enhance Natural Killer
Cell (NK) Activity. This Is Very Beneficial
During The Ageing Process.
Healthy Trac™ Naturally Stimulates The
Immune System By Increasing Most Immune
Cell Populations Including Monocytes And
Dendritic Cells.
Immune System Benefits
In-Vitro Human Testing.
Macrophage Proliferation
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Healthy Trac™
Stimulates Macrophage
Proliferation
More Powerful Than
Echinacea In Side-BySide Testing
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100
cells
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80
Ech
AG
60
40
20
0
ug/ml
Stimulation of Human Natural Killer
Cytotoxicity Against K562 Tumor Cells
60
50
Mononuclear cells
40
% Specific
cytotoxicity 30
Non-adherent cells
20
Monocytes
macrophages
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0.1
0.5
1
mg/ml Arabinogalactan
In vitro Evaluation Of AG As An
Adjunct to Cancer Therapy.
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2 to 6 Times Greater NK Cell Cytotoxicity
Against K562 Tumor Cells Through The
Stimulation of Gamma Interferon Production.
Increased Production of Tumor Necrosis
Factor (TNF) Alpha, Interleukin (IL) 1 And 6.
TNF Alpha is Also Toxic to Tumor Cells.
IL-1 And 6 Increase Vascular Permeability.
SWCRI Immune System
Activation - Properdin
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Properdin is a Natural Activator of The
Immune System’s Complement Pathway.
Properdin is an Accurately Measurable
Immune System Marker.
Responsible For Non-specific Host Defense
Mechanisms, Including Defense Against Cold
And Flu.
Overall Profound Immunostimulatory Effects.
Properdin Increase.
Increase (%)
300
250
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100
P = Placebo
SEE = Standardized Echinacea
Extract 4% Phenols
EWH = Echinacea Whole Herb
3.5% Phenols
AG = Arabinogalactan
50
0
P
SEE
EWH
Supplement
AG
Human Clinical Research: No Adverse
Reaction In Any Clinical Trial.
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Health East, 2001, 500 Children, 12 Weeks.
University of Florida, 2000, 33 Subjects, 6 Weeks.
University of Minnesota, 2000, 100 Subjects, 23
Weeks.
SWC Research Institute, 1999, 48 Subjects, 4 Weeks.
SWC Research Institute, 1999, 24 Subjects, 4 Weeks.
University of Minnesota, 1998, 22 Subjects, 6 Weeks.
Scientific Evidence.
Journal Papers And Clinical
Studies