Endocrine System
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Transcript Endocrine System
Endocrine System
A chemical
communication system of
the body tissue
Types of communication
• Gap Junctions: similar to pores that are
connected, allow signal molecules to pass from
cell to cell
• Neurotransmitters
• Paracrines (Local hormones): a cell of tissue
that stimulates other cells around them with
secretion
• Hormones: chemical messenger that travels
through blood and stimulates target cells
Hypothalamus & Pituitary Gland
Most
important glands in system they have
the largest effect on bodily functions
They are closely related the pituitary sits
on a structure of the hypothalamus. The
hypothalamus often acts through the
neurohypophysis(posterior pituitary)
Hypothalamus
Is
connected to the third ventricle of the
brain
It regulates primitive body functions from
hydration to sex drive
It produces 9 hormones five that stimulate
the pituitary, two that inhibits and two that
are secreted through the posterior
pituitary(oxytocin (OT), antidiuretic
hormone (ADH))
Pituitary Gland
Made
of two parts the adenohypophysis
and neurohypophysis
Adenohypophysis: also known as the
anterior lobe. It has no nervous connection
it only responds to hormone interaction
Neurohypophysis: posterior lobe. It is only
¼ the size of the anterior lobe. It has
nervous connection and is not a true gland
it is a collection of different tissue.
Contains the hypothalamic stalk.
Pituitary Hormones
Most
of the pituitary hormones are trophic
hormones
Trophic hormones: stimulates other
endocrine organs to secrete their own
hormones
Axis: the interaction between the
hypothalamus, pituitary and a remote
endocrine gland. (There are 3 different
axis)
Posterior Pituitary Lobe
It
doesn’t produce any hormones it just
stores two OT and ADH
OT: causes contraction of the uterus
darning Birth, contraction of lactation,
contraction during sexual response
ADH: Controls hydration and
vasoconstriction
Anterior Lobe
Follicle
Stimulating Hormone(FSH):
targets gonads causes the development of
eggs and sperm
Luteinizing Hormone(LH): targets gonads
in females causes ovulation, in males
cause production of testosterone
Thyrotropin(TSH): targets thyroid effects
metabolism
Anterior Lobe
Corticotropin(ACTH):
targets adrenal
cortex effects sugar, fat and protein
metabolism (“cortisol”)
Prolactin(PRL): targets mammary glands
increase in number and production
Growth Hormone(GH): targets all tissue
is produced 1000 times more than any
other hormone promotes mitosis thus
tissue growth