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Serpiginous choroiditis/Geographic
helicoid peripapillary choroidopathy
(GHPC)
Dr. Rathinam Sivakumar
HOD - Uveitis Services
Aravind Eye Hospital, Madurai
India
Ocular History
19 year old male, engineering
student
presented with c/o sudden onset
painless progressive defect of
vision in OD since 5 days
no similar complains in the past
General History
No
No
No
No
No
No
h/o
h/o
h/o
h/o
h/o
h/o
trauma
cough, fever, weight loss in recent past
urogenital ulcerations
bleeding discariasis
neurological symptoms
any systemic illness
General examination
patient moderately built and fairly nourished
conscious, co-operative, oriented to time, place and person
afebrile
no joint swellings
no rashes, nodules, vesicles
no pallor, icterus, cyanosis or lymphadenopathy
BP-110/80 mm Hg
pulse -80 /min, regular, good volume, equal on both sides
General Examination
CVS - Normal
RS - Normal
Abdomen – Normal
CNS – No focal neurological deficit
Visual Acuity (Snellen’s)
OD-6/60
OS-6/6
Ocular Examination
Lids
Conjunctiva
OD
OS
Normal
Normal
NormalExamination
Normal
Ocular
–
Cornea
Clear
Clear
Anterior Chamber
Normal Depth
Normal Depth
Iris
Normal Colour and Pattern Normal Colour and Pattern
Pupil
Normal size and reacting to
light
Normal size and reacting
to light
Lens
Clear
Clear
Ocular Movements
Full
Full
Fundus
OD:
OS:
Yellow arrow- healed lesions
Red arrow-active lesion over macula
healed chorioretinal scars
FFA- Active stage
“Block early, stain late”
FFA
Distinctly insidious
Chronic
Recurrent
variable in size and shape,
variable stages of progression,
Serpiginous choroiditis
Investigations
TLC - 9,600 cells/cumm
DLC – N 58%/ L 30%/ E 12 %
RBC - 3.4 million cells/cumm
Hb – 13.4 gm%
ESR 4mm-30min, 10 mm in 1 hr
Fasting sugar - 73 mg %
Blood urea - 14 mg%
Serum creatinine - 0.9 mg%
Tuberculin skin test (5 ppd) - negative
TPHA – negative
HIV - negative
Diagnosis
Serpiginious chorioretinitis
not associated to systemic disorders
Diagnosis based on
Clinical picture
FFA findings
Investigations
Negative tuberculin skin test
Negative VDRL
Normal spiral CT chest
Treatment
Oral prednisolone 60mg OD
in tapering doses
Follow ups of the OS
June 27, 2009
2 weks later
3 weeks later
no recurrences
6/60
6/36
6/24
Symptoms
Asymptomatic if
macula is spared
Onset
chronic recurrent
GHPC
course
FFA Active stage
FFA Healed stage
prognosis
Often we see a previous scar
Early hypo and
leak late
Central hypo
and leaking borders
Vision loss > 2 lines