Transcript Thyroid Function and Lyme disease

Wilson’s Temperature Syndrome
and
Lyme disease
Dr. Tedde Rinker
Stress Medicine Consulting
www.stress-medicine.com
Copyright, Dr. Tedde Rinker 2/23/2010
Wilson Temperature Syndrome
 Denis Wilson, MD, a GP in rural Florida
 Developed protocol over several years
 Of clinical observations and treatment
 Found lab tests often didn’t match patient’s
symptoms.
 Discovered a method to restore “normal”
temperatures, eliminate low thyroid
symptoms, and eventually stop taking thyroid
hormones.
Copyright, Dr. Tedde Rinker
2/23/2010
Symptoms of low thyroid
 Low body temperature
 Dry brittle hair, nails
 Feels cold, cold hands
 Puffy eyes, eyebrow hair
and feet
 Dry, itchy skin
 Fatigue

 Poor sleep quality
 Hair loss



loss lateral 1/3
Aching muscles and
joints, weakness
Depressed, low
motivation
Concentration and
memory problems
Weight gain, constipation
Copyright, Dr. Tedde Rinker
2/23/2010
Copyright, Dr. Tedde Rinker
2/23/2010
Most Important Tools for WTS
 Scored symptom list
 Temperature Chart
 Lab Testing
Copyright, Dr. Tedde Rinker
2/23/2010
Scored Symptom List
 60 symptoms listed, score 1-10
 Score of 600= perfect health
 Score <350 = likely thyroid problem
 Score >350 but <500 =likely hormonal
 Score 10 for “not a symptom”
 Score 1 for serious, worst symptom
Copyright, Dr. Tedde Rinker
2/23/2010
Temperature Chart
 Prior to treatment take temperature 3
times a day for 5-10 days
 Use reliable, accurate thermometer
 Start 2 or more hours after waking
 Last temp of day should be more than 3
hours before bed
Copyright, Dr. Tedde Rinker
2/23/2010
Laboratory Testing
 Should test both Adrenal and Thyroid function
 Thyroid Labs: Free T3, Free T4, Reverse T3,
TSH, TPO antibodies, and Thyroglobulin
antibodies (For hyperthyroid, should also get
TSH receptor antibodies)
 Adrenal Testing: 4-point saliva cortisol testing in
am, noon, mid afternoon and bedtime.
Copyright, Dr. Tedde Rinker
2/23/2010
Why do we want optimal
daytime temperatures?
 Enzyme activity throughout the body is
temperature sensitive.
 Metabolic rate of all organ systems are
enzyme and temperature dependent.
 Detoxification pathways slow down with
low body temperature.
Copyright, Dr. Tedde Rinker
2/23/2010
Optimal Daytime Temperatures
 98.2-98.6 (F) 90- 100% metabolic activity
 97.5-98.1 (F) 55-75% metabolic activity,
expect these temps at night.
 < 95.6- 97.4 (F) 50% or lower metabolic
activity.
Copyright, Dr. Tedde Rinker
2/23/2010
TSH
T4
Conventional Medical View is that you only need this
limited amount of information to diagnose and treat.
Copyright, Dr. Tedde Rinker
2/23/2010
T4
TPO Ab
EVENTS
TG Ab
STRESS
TRAUMA
TOXICITY
INFECTION
INLAMMATION
STARVATION
SUDDEN HORMONE CHANGE
TG-T4
T4-TG
T3
5’ DEIODINASE
SELENIUM
FT3
F
5 DEIODINASE
F
F
F
F
F
R
R
R
F
R
F
F
F
F
R R
F
Copyright, Dr. Tedde Rinker
2/23/2010
R
REVERSE T3
RT3
(not active)
Stress-induced Thyroid Dysfunction
Stress
Hypothalamus
Hypothalamus
CRH
TRH
Pituitary
Pituitary
ACTH
Cortisol
TSH
Adrenal Cortex
Adrenal Medulla
Thyroid
Adrenaline
T4
Cell
Copyright, Dr. Tedde Rinker
2/23/2010
T3
Adrenal Fatigue Due to Low
Thyroid Function
Pregnenolone
Progesterone
DHEA-S
Testosterone
Androstenedione
Increased levels followed by depletion
as stress or low thyroid continues to
lead to Adrenal Fatigue.
Copyright, Dr. Tedde Rinker
2/23/2010
Helpful Nutrients for Thyroid
Function
 Improve T4 production:
 Tyrosine, Iodine, Zinc, Vitamin E, Vit A, B-2,B3, B-6 and Vitamin C
 Improve conversion of T4- T3:
 Zinc and Selenium
 Adequate Progesterone
 Adequate Melatonin
 Improves T3 receptor site binding:
 Vitamin A
Copyright, Dr. Tedde Rinker
2/23/2010
Conventional Medical Interventions
 Thyroid: Synthriod™, Levoxyl™,
 Thyroxine (T4)
 Cytomel™ (short acting T3)
 Armour thyroid (both T4 and T3)
 Adrenals: Predisone, Cortef™ (hydrocortisone)
Copyright, Dr. Tedde Rinker
2/23/2010
Integrative Approach
 Get a complete history
 Take Temperatures (temp chart)
 A complete thryoid/adrenal panel
 Examine causative factors
 Take steps to restore balance in the
system.
Copyright, Dr. Tedde Rinker
2/23/2010
What should we do first?
 Give Levoxyl, Synthroid (T4)?
 Radiate the thyroid gland?
 Give Armour thyroid?
 Give T3 ?
 Give Cortisol/cortisone?
 Suppress cortisol production?
 Send the patient to a psychiatrist?
 Tell patient “There’s nothing wrong with
you!”
Copyright, Dr. Tedde Rinker
2/23/2010
WTS Protocol
 Uses 12-hour Sustained -release T3
 Graduated dosing, increasing dose daily by 7.5
mcg every 12 hours (0.625 mcg/hr)
 Until average temperature is at 98.6 or patient
reaches 75 mcg every 12 hours (6.25 mcg/hr), or
patient has negative symptoms
 Hold at max. tolerable dose for 3 weeks, then
cycle down (more slowly) to no SRT3 for two
days. If temperature drops, begin cycling up
again, daily increasing dose.
Copyright, Dr. Tedde Rinker
2/23/2010
In the best circumstance
 With each successive cycle:
 It should take a lower dose to “capture”
temperature at 98.6
 Temperature should stay close to 98.6 as
dosage is cycled down
 Until, at zero medication, temperature
maintains daytime average around 98.6 and
symptoms have resolved.
Copyright, Dr. Tedde Rinker
2/23/2010
Copyright, Dr. Tedde Rinker
2/23/2010
Copyright, Dr. Tedde Rinker
2/23/2010
When Cycling up is “bad”
 If patient starts to cycle up, and within days or
the first week feels even worse than before she
started, suspect:
 Adrenal Fatigue (over stimulated or worse fatigue)
 Metal Toxicity (overt symptoms of metal toxicity)
 Chronic Infection (infectious symptoms become acute, or
obvious for the first time)
Copyright, Dr. Tedde Rinker
2/23/2010
Copyright, Dr. Tedde Rinker
2/23/2010
When WTS protocol makes
patient feel worse:
 If the problem that precipitated the WTS is not
resolved:
 The body is not yet ready for a ramped up
metabolism
 The down-regulation was done for a reason. It’s
important to remember that
 This is also the time that the patient will need
extra support, so they won’t give up. It doesn’t
mean they can’t benefit from SRT3 treatment.
Copyright, Dr. Tedde Rinker
2/23/2010
When Lyme and WTS Present
 Cautious ramping of thyroid (SRT3)
 Adaptogens to support adrenals
 Remove toxins carefully (slowly)
 Support low stress lifestyle
 Eliminate factors that increase RT3
 Treat the infections
Copyright, Dr. Tedde Rinker
2/23/2010
T4
TPO Ab
EVENTS
STRESS (overtaxed, untreated)
TRAUMA (chronic illness, surgery, loss)
TOXICITY (mercury, Lyme toxins)
INFECTION (Lyme & co-infections)
INFLAMMATION (Herx, immune resp.)
STARVATION
SUDDEN HORMONE CHANGE
child birth, menopause
TG Ab
TG-T4
FREE T3
5’ DEIODINASE
SELENIUM
FT3
F
5 DEIODINASE
F
F
F
F
F
R
R
R
F
R
F
F
F
F
R R
F
Copyright, Dr. Tedde Rinker
2/23/2010
R
T4-TG
REVERSE T3
RT3
(not active)
Thank You!
Questions?
Dr. Tedde Rinker
650-964-6700
www.stress-medicine.com
Copyright, Dr. Tedde Rinker 2/23/2010